PDB: 2023 件ウェブページステータス検索Chemie searchBIRD

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6ZTF	Crystal Structure of the anti-human P-Cadherin Fab CQY684 分子名称: CQY684 Fab heavy-chain, CQY684 Fab light-chain 著者 Rondeau, J.M, Lehmann, S. 登録日 2020-07-20 公開日 2021-05-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
7CMF	Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) 分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3 著者 Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. 登録日 2020-07-27 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
7CME	Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) 分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... 著者 Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. 登録日 2020-07-27 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
7UQU	Crystal Structure of Mouse Cadherin-23 EC9 分子名称: CALCIUM ION, Cadherin-23 著者 Sandhu, J.S, De La Torre, P, Sotomayor, M. 登録日 2022-04-20 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.976 Å) 主引用文献 Crystal Structure of Mouse Cadherin-23 EC9 To be published
7N86	Crystal Structure of Human Protocadherin-24 EC1-2 Form II 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Modak, D, Gray, M.E, Sotomayor, M. 登録日 2021-06-13 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.175 Å) 主引用文献 Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent. Plos Biol., 19, 2021
5MV7	Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain 分子名称: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb 著者 Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-15 公開日 2017-07-05 最終更新日 2022-03-30 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
7SCM	Crystal Structure of Ancestral Amniote Cadherin-23 EC1-2 分子名称: CALCIUM ION, Cadherin 23, POTASSIUM ION, ... 著者 Nisler, C.R, Sotomayor, M. 登録日 2021-09-28 公開日 2022-10-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.272 Å) 主引用文献 Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
7SB6	Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 分子名称: CALCIUM ION, CHLORIDE ION, Cadherin 23, ... 著者 Nisler, C.R, Narui, Y, Sotomayor, M. 登録日 2021-09-23 公開日 2022-10-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.588 Å) 主引用文献 Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
7SGX	Crystal Structure of Turtle Cadherin-23 EC1-2 分子名称: CALCIUM ION, CHLORIDE ION, Cadherin 23, ... 著者 Nisler, C.R, Sotomayor, M. 登録日 2021-10-07 公開日 2022-10-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
4XXW	Crystal structure of mouse Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 splice variant 分子名称: CALCIUM ION, CHLORIDE ION, Cadherin-23, ... 著者 Narui, Y, Sotomayor, M. 登録日 2015-01-31 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.261 Å) 主引用文献 Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15. Biochemistry, 57, 2018
8H62	Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12 分子名称: ACETATE ION, CALCIUM ION, Cadherin-1, ... 著者 Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. 登録日 2022-10-14 公開日 2023-10-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes. J.Biol.Chem., 299, 2023
6LX0	Structure of Leptospira santarosai serovar shermani LRR protein LSS11580 分子名称: Membrane protein 著者 Chu, C.H, Hsu, S.H, Yang, C.W, Sun, Y.J. 登録日 2020-02-10 公開日 2020-12-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal structure of Leptospira leucine-rich repeat 20 reveals a novel E-cadherin binding protein to induce NGAL expression in HK2 cells. Biochem.J., 477, 2020
2KBQ	Solution structure of harmonin N terminal domain 分子名称: Harmonin 著者 Zhang, M, Pan, L, Yan, J, Wu, L. 登録日 2008-12-05 公開日 2009-03-31 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 Proc.Natl.Acad.Sci.USA, 106, 2009
1Q5C	S-S-lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 He, W, Cowin, P, Stokes, D.L. 登録日 2003-08-06 公開日 2003-10-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (30 Å) 主引用文献 Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
1Q5B	lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 He, W, Cowin, P, Stokes, D.L. 登録日 2003-08-06 公開日 2003-10-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (30 Å) 主引用文献 Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
1Q5A	S-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 He, W, Cowin, P, Stokes, D.L. 登録日 2003-08-06 公開日 2003-10-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (30 Å) 主引用文献 Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
1Q55	W-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 He, W, Cowin, P, Stokes, D.L. 登録日 2003-08-06 公開日 2003-10-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (30 Å) 主引用文献 Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
5FCS	Diabody 分子名称: Diabody, SULFATE ION 著者 Mosyak, L, Root, A. 登録日 2015-12-15 公開日 2016-12-14 最終更新日 2019-11-13 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer. Antibodies, 5, 2016
3FF9	Structure of NK cell receptor KLRG1 分子名称: Killer cell lectin-like receptor subfamily G member 1 著者 Li, Y, Mariuzza, R.A. 登録日 2008-12-02 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity, 31, 2009
8EGW	Complex of Fat4(EC1-4) bound to Dchs1(EC1-3) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Medina, E, Luca, V.C. 登録日 2022-09-13 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
8EGX	Complex of Fat4(EC1-4) bound to Dchs1(EC1-4) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Medina, E, Luca, V.C. 登録日 2022-09-13 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.688 Å) 主引用文献 Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
5GW0	Crystal structure of SNX16 PX-Coiled coil 分子名称: Sorting nexin-16 著者 Xu, J, Liu, J. 登録日 2016-09-08 公開日 2017-09-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding. Structure, 25, 2017
5GW1	Crystal structure of SNX16 PX-Coiled coil in space group P212121 分子名称: Sorting nexin-16 著者 Xu, J, Liu, J. 登録日 2016-09-08 公開日 2017-09-13 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding. Structure, 25, 2017

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