6NLH
| Structure of human triose phosphate isomerase R189A | 分子名称: | BROMIDE ION, PHOSPHATE ION, SODIUM ION, ... | 著者 | Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P. | 登録日 | 2019-01-08 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. Biochim Biophys Acta Mol Basis Dis, 1865, 2019
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7RSS
| Kod-RI incorporating DNA, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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6NSX
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7RSR
| Kod-RI incorporating PMT, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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6O3F
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7SJN
| HtrA1:Fab15H6.v4 complex | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | 登録日 | 2021-10-18 | 公開日 | 2022-09-07 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration. Nat Commun, 13, 2022
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7RTI
| X-ray structure of RBPJ-L3MBTL3(dT62)-DNA complex | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | 登録日 | 2021-08-13 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3. Nucleic Acids Res., 50, 2022
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7RZ3
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6NK1
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6NLZ
| Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment degradation product B9D | 分子名称: | ATP-dependent dethiobiotin synthetase BioD, SULFATE ION, [(1R,2S)-2-(2-hydroxybenzene-1-carbonyl)cyclopentyl]acetic acid, ... | 著者 | Thompson, A.P, Polyak, S.W, Wegener, K.L, Bruning, J.B. | 登録日 | 2019-01-10 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment degradation product B9D To Be Published
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7S01
| X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | 著者 | Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V. | 登録日 | 2021-08-28 | 公開日 | 2022-07-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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6NN0
| Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with 2'-deoxycytidine and fragment degradation product B9D | 分子名称: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ATP-dependent dethiobiotin synthetase BioD, SULFATE ION, ... | 著者 | Thompson, A.P, Polyak, S.W, Wegener, K.L, Bruning, J.B. | 登録日 | 2019-01-14 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with 2'-deoxycytidine and B9D To Be Published
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7SJO
| HtrA1S328A:Fab15H6.v4 complex | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | 登録日 | 2021-10-18 | 公開日 | 2022-09-07 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration. Nat Commun, 13, 2022
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7SDM
| [U:Ag+:S] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(IMC)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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6NB8
| Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment | 分子名称: | S230 antigen-binding (Fab) fragment, heavy chain, light chain | 著者 | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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7SD7
| [C:Hg2+:T] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.68 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDN
| [C:Ag+:U] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.32 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDT
| [iU:Ag+:S] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5IU)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(IMC)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SBZ
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7SDF
| [C:Ag+:S] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(IMC)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDX
| [U:Hg2+:mC] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*UP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5CM)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SE2
| [C:Ag+:mC] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5CM)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.03 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDG
| [C:Ag+:C] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDJ
| [mC:Ag+:mC] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5CM)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5CM)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7SDQ
| [mC:Ag+:U] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5CM)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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