6O3F

Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand

Summary for 6O3F

• Entry DOI: 10.2210/pdb6o3f/pdb
• Related: 6HCU 6HCW
• Descriptor: Lysine--tRNA ligase, ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, 1,2-ETHANEDIOL, ... (8 entities in total)
• Functional Keywords: ssgcid, krs, nucleotide binding, aminoacyl trna ligase activity, lysine trna ligase activity, atp binding, lysyl trna aminoacylation, strain uch-1/proctitis, strain d/uw-3/cx, structural genomics, seattle structural genomics center for infectious disease, ligase
• Biological source: Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
• Total number of polymer chains: 2
• Total formula weight: 125164.83

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-02-26, release date: 2019-03-27, Last modification date: 2023-10-11)

• Primary citation: Dranow, D.M.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand; to be published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)