Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004824 | molecular_function | lysine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004824 | molecular_function | lysine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue FYB A 701 |
| Chain | Residue |
| A | ARG271 |
| A | ASN441 |
| A | GLY493 |
| A | ILE494 |
| A | GLY495 |
| A | ARG498 |
| A | ILE509 |
| A | LYS720 |
| A | HOH886 |
| A | GLU273 |
| A | THR278 |
| A | HIS279 |
| A | ASN280 |
| A | PHE283 |
| A | MET285 |
| A | GLU438 |
| A | LEU439 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| A | ILE28 |
| A | ASN29 |
| A | PRO32 |
| A | LEU153 |
| A | HOH897 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 703 |
| Chain | Residue |
| A | PHE76 |
| A | ILE120 |
| A | GLU121 |
| A | LEU124 |
| A | LEU126 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 704 |
| Chain | Residue |
| A | ARG203 |
| A | GLU213 |
| A | GLU215 |
| B | LEU199 |
| B | ARG203 |
| B | EDO703 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | LEU219 |
| A | GLN220 |
| A | THR221 |
| A | EDO718 |
| B | PHE515 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 706 |
| Chain | Residue |
| A | ILE474 |
| A | ASP475 |
| A | GLU476 |
| A | GLU477 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 707 |
| Chain | Residue |
| A | MET343 |
| A | ASP392 |
| A | GLU431 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 708 |
| Chain | Residue |
| A | TYR205 |
| A | ASN304 |
| A | ARG311 |
| B | PRO467 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 709 |
| Chain | Residue |
| A | MET299 |
| A | GLU303 |
| A | PRO337 |
| A | TRP338 |
| A | ARG340 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 710 |
| Chain | Residue |
| A | TYR350 |
| A | LYS398 |
| A | LEU399 |
| A | ILE400 |
| A | ALA401 |
| A | HIS403 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 711 |
| Chain | Residue |
| A | LYS437 |
| A | GLU438 |
| A | ARG498 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 712 |
| Chain | Residue |
| A | LEU450 |
| A | ARG453 |
| A | CYS483 |
| B | TYR7 |
| B | LEU8 |
| B | TYR13 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 713 |
| Chain | Residue |
| A | GLY224 |
| A | GLY225 |
| A | ALA226 |
| A | GLU227 |
| A | GLN459 |
| A | ASP475 |
| A | SO4715 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 714 |
| Chain | Residue |
| A | LYS66 |
| A | VAL67 |
| A | ARG68 |
| A | GLU133 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 715 |
| Chain | Residue |
| A | ALA226 |
| A | GLU227 |
| A | THR412 |
| A | ARG429 |
| A | ASN441 |
| A | TYR443 |
| A | PEG713 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 716 |
| Chain | Residue |
| A | HIS10 |
| A | ASP12 |
| A | ILE159 |
| A | SER160 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 717 |
| Chain | Residue |
| A | ASP207 |
| A | SER210 |
| A | PHE211 |
| A | LEU212 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 718 |
| Chain | Residue |
| B | PHE515 |
| A | GLN220 |
| A | ALA251 |
| A | LYS254 |
| A | EDO705 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 719 |
| site_id | AE2 |
| Number of Residues | 14 |
| Details | binding site for residue LYS A 720 |
| Chain | Residue |
| A | GLY225 |
| A | ALA226 |
| A | SER247 |
| A | GLU249 |
| A | ARG271 |
| A | GLU287 |
| A | TYR289 |
| A | ASN441 |
| A | TYR443 |
| A | GLU445 |
| A | GLY491 |
| A | GLY493 |
| A | FYB701 |
| A | HOH864 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 701 |
| Chain | Residue |
| A | TYR7 |
| A | LEU8 |
| A | TYR13 |
| B | PRO449 |
| B | LEU450 |
| B | ARG453 |
| B | LEU479 |
| B | CYS483 |
| site_id | AE4 |
| Number of Residues | 18 |
| Details | binding site for residue FYB B 702 |
| Chain | Residue |
| B | ARG271 |
| B | GLU273 |
| B | THR278 |
| B | HIS279 |
| B | ASN280 |
| B | PHE283 |
| B | MET285 |
| B | GLU438 |
| B | LEU439 |
| B | ASN441 |
| B | GLY493 |
| B | ILE494 |
| B | GLY495 |
| B | ARG498 |
| B | ILE509 |
| B | LYS724 |
| B | HOH831 |
| B | HOH882 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 703 |
| Chain | Residue |
| A | LEU199 |
| A | ARG203 |
| A | EDO704 |
| B | GLU213 |
| B | GLU215 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 704 |
| Chain | Residue |
| A | PHE515 |
| B | GLN220 |
| B | ALA251 |
| B | LYS254 |
| B | EDO707 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 705 |
| Chain | Residue |
| B | PHE76 |
| B | ILE120 |
| B | GLU121 |
| B | LEU124 |
| B | HOH841 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 706 |
| Chain | Residue |
| B | PRO162 |
| B | ASP170 |
| B | ARG174 |
| B | ALA180 |
| B | HOH893 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 707 |
| Chain | Residue |
| A | PHE515 |
| B | LEU219 |
| B | THR221 |
| B | EDO704 |
| B | HOH905 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 708 |
| Chain | Residue |
| B | GLU273 |
| B | GLY274 |
| B | ASP276 |
| B | HIS279 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 709 |
| Chain | Residue |
| B | LYS437 |
| B | GLU438 |
| B | ARG498 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 710 |
| Chain | Residue |
| B | ASP392 |
| B | GLU431 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 711 |
| Chain | Residue |
| B | LEU410 |
| B | GLU411 |
| B | THR413 |
| B | PRO414 |
| B | LEU455 |
| B | GLN459 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 712 |
| Chain | Residue |
| B | ARG61 |
| B | GLY167 |
| B | LEU168 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 713 |
| Chain | Residue |
| B | ASP187 |
| B | THR191 |
| B | THR504 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 714 |
| Chain | Residue |
| B | ASP276 |
| B | ARG277 |
| B | SER508 |
| B | ARG510 |
| B | HOH834 |
| B | HOH872 |
| site_id | AF8 |
| Number of Residues | 10 |
| Details | binding site for residue PG4 B 715 |
| Chain | Residue |
| B | GLY224 |
| B | GLY225 |
| B | GLU227 |
| B | ILE250 |
| B | THR412 |
| B | ARG429 |
| B | TYR443 |
| B | GLN459 |
| B | ASP475 |
| B | HOH829 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 716 |
| Chain | Residue |
| B | TYR350 |
| B | LYS398 |
| B | ILE400 |
| B | ALA401 |
| B | HIS403 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 717 |
| Chain | Residue |
| B | GLU368 |
| B | THR371 |
| B | LEU373 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 718 |
| Chain | Residue |
| B | ARG277 |
| B | TYR322 |
| B | LEU325 |
| B | LYS437 |
| B | ALA507 |
| site_id | AG3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 719 |
| Chain | Residue |
| B | HIS10 |
| B | ASP12 |
| B | TYR13 |
| B | ILE159 |
| B | SER160 |
| B | HOH903 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 720 |
| Chain | Residue |
| A | ARG420 |
| A | HOH941 |
| B | PRO32 |
| B | TYR33 |
| B | GLN34 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 721 |
| Chain | Residue |
| B | MET299 |
| B | GLU303 |
| B | PRO337 |
| B | TRP338 |
| B | ARG340 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 722 |
| Chain | Residue |
| B | ASP423 |
| B | HOH900 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 723 |
| site_id | AG8 |
| Number of Residues | 12 |
| Details | binding site for residue LYS B 724 |
| Chain | Residue |
| B | GLY225 |
| B | ALA226 |
| B | SER247 |
| B | GLU249 |
| B | ARG271 |
| B | GLU287 |
| B | TYR289 |
| B | ASN441 |
| B | TYR443 |
| B | GLU445 |
| B | FYB702 |
| B | HOH831 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00252","evidenceCode":"ECO:0000255"}]} |
