6O3F
Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine--tRNA ligase | polymer | 529 | 60609.4 | 2 | UniProt (B0BAN6) Pfam (PF01336) Pfam (PF00152) | Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) | Lysyl-tRNA synthetase,LysRS |
| 2 | C, X (A, B) | ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide | non-polymer | 355.3 | 2 | Chemie (FYB) | |||
| 3 | AA, BA, CA, D, DA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 30 | Chemie (EDO) | |||
| 4 | EA, HA, L, LA, M... (B, A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 5 | NA, O (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | TA, V (B, A) | LYSINE | non-polymer | 147.2 | 2 | Chemie (LYS) | |||
| 7 | KA (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | UA, VA (A, B) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 521 (UniProt: B0BAN6)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 121218.9 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 3946.0 | |
| All* | Total formula weight | 125164.8 |
