7NJG
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![BU of 7njg by Molmil](/molmil-images/mine/7njg) | Xylose isomerase grown inside HARE serial crystallography chip | 分子名称: | COBALT (II) ION, Xylose isomerase | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | 登録日 | 2021-02-16 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip. Acta Crystallogr D Struct Biol, 77, 2021
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8BD0
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7N63
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![BU of 7n63 by Molmil](/molmil-images/mine/7n63) | X-ray structure of HCAN_0200, an aminotransferase from Helicobacter canadensis in complex with its external aldimine | 分子名称: | (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Griffiths, W.A, Heisdorf, C.J, Thoden, J.B, Holden, H.M. | 登録日 | 2021-06-07 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
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7NJI
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![BU of 7nji by Molmil](/molmil-images/mine/7nji) | HEX1 (in cellulo) loaded on HARE serial crystallography chip | 分子名称: | Woronin body major protein | 著者 | Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C. | 登録日 | 2021-02-16 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip. Acta Crystallogr D Struct Biol, 77, 2021
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4ZF7
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![BU of 4zf7 by Molmil](/molmil-images/mine/4zf7) | Crystal structure of ferret interleukin-2 | 分子名称: | DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... | 著者 | Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. | 登録日 | 2015-04-21 | 公開日 | 2015-11-04 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | Structural and functional characterisation of ferret interleukin-2. Dev.Comp.Immunol., 55, 2015
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6XX1
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![BU of 6xx1 by Molmil](/molmil-images/mine/6xx1) | The unique CBM3-Clocl_1192 of Hungateiclostridium clariflavum | 分子名称: | Cellulose binding domain-containing protein | 著者 | Milana, M.V, Almog, R, Yaniv, O, Oded, L, Inna, R.G, Felix, F, Edward, A.B, Raphael, L. | 登録日 | 2020-01-26 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | The unique CBM3-Cthe_0271 from Ruminoclostridium thermocellum and CBM3-Clocl_1192 from Hungateiclostridium clariflavum To Be Published
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4ZNU
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![BU of 4znu by Molmil](/molmil-images/mine/4znu) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Methyl-substituted OBHS derivative | 分子名称: | 2-methylphenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate, Estrogen receptor, Nuclear receptor-interacting peptide | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-05-05 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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6ZP8
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![BU of 6zp8 by Molmil](/molmil-images/mine/6zp8) | Yeast 20S proteasome in complex with glidobactin-like natural product HB335 | 分子名称: | (2~{S},3~{R})-~{N}-[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]-3-oxidanyl-2-(3-phenylpropanoylamino)butanamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Zhao, L, Le Chapelain, C, Brachmann, A.O, Kaiser, M, Groll, M, Bode, H.B. | 登録日 | 2020-07-08 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii. Chembiochem, 22, 2021
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8BEO
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![BU of 8beo by Molmil](/molmil-images/mine/8beo) | Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, ... | 著者 | Shaanan, B, Binshtein, E. | 登録日 | 2022-10-21 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP To Be Published
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8BHQ
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![BU of 8bhq by Molmil](/molmil-images/mine/8bhq) | GABA-A receptor a5 homomer - a5V3 - RO7172670 | 分子名称: | 2-[[5-methyl-3-(6-methylpyridazin-3-yl)-1,2-oxazol-4-yl]methyl]-5-(5-oxa-2-azaspiro[3.5]nonan-2-yl)pyridazin-3-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5 | 著者 | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Kasaragod, V.B. | 登録日 | 2022-10-31 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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6ZP6
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![BU of 6zp6 by Molmil](/molmil-images/mine/6zp6) | Yeast 20S proteasome in complex with glidobactin-like natural product HB334 | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | 著者 | Zhao, L, Le Chapelain, C, Brachmann, A.O, Kaiser, M, Groll, M, Bode, H.B. | 登録日 | 2020-07-08 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii. Chembiochem, 22, 2021
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5ZWB
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![BU of 5zwb by Molmil](/molmil-images/mine/5zwb) | Crystal structure of Pyridoxal kinase (PdxK) from Salmonella typhimurium in complex with ADP, PL-linked to Lys233 via a Schiff base | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Deka, G, Benazir, J.F, Kalyani, J.N, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2018-05-14 | 公開日 | 2019-05-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional studies on Salmonella typhimurium pyridoxal kinase: the first structural evidence for the formation of Schiff base with the substrate. Febs J., 286, 2019
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6OBT
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![BU of 6obt by Molmil](/molmil-images/mine/6obt) | Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases | 分子名称: | Borrelidin polyketide synthase, type I | 著者 | McAndrew, R.P, Barajas, J.F, Pereira, J.H, Keasling, J.D, Adams, P.D. | 登録日 | 2019-03-21 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases. J Ind Microbiol Biotechnol., 46, 2019
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6DFN
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![BU of 6dfn by Molmil](/molmil-images/mine/6dfn) | Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa | 分子名称: | (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, (8S)-8-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepine-5,11-diol, Estrogen receptor, ... | 著者 | Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Ortwine, D.F, Nettles, K.W, Nwachukwu, J.C. | 登録日 | 2018-05-15 | 公開日 | 2019-02-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorg. Med. Chem. Lett., 29, 2019
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7UHC
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6ZOU
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![BU of 6zou by Molmil](/molmil-images/mine/6zou) | Yeast 20S proteasome in complex with glidobactin-like natural product HB333 | 分子名称: | 11-methyl-~{N}-[(2~{S},3~{R})-1-[[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]amino]-3-oxidanyl-1-oxidanylidene-butan-2-yl]dodecanamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Zhao, L, Le Chapelain, C, Brachmann, A.O, Kaiser, M, Groll, M, Bode, H.B. | 登録日 | 2020-07-07 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii. Chembiochem, 22, 2021
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7CYV
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![BU of 7cyv by Molmil](/molmil-images/mine/7cyv) | Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD) | 分子名称: | Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D. | 登録日 | 2020-09-04 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody. Embo Mol Med, 13, 2021
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5KD6
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5KDN
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![BU of 5kdn by Molmil](/molmil-images/mine/5kdn) | ZmpB metallopeptidase from Clostridium perfringens | 分子名称: | 1,2-ETHANEDIOL, F5/8 type C domain protein, ZINC ION | 著者 | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | 登録日 | 2016-06-08 | 公開日 | 2017-01-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5DL8
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8BHR
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![BU of 8bhr by Molmil](/molmil-images/mine/8bhr) | GABA-A receptor a5 homomer - a5V3 - RO7015738 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy]-~{N}-[(2~{S})-1-oxidanylpentan-2-yl]pyridine-3-carboxamide, Gamma-aminobutyric acid receptor subunit alpha-5 | 著者 | Miller, P.S, Malinauskas, T.M, Kasaragod, V.B. | 登録日 | 2022-10-31 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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4Z3F
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![BU of 4z3f by Molmil](/molmil-images/mine/4z3f) | Crystal structure of the lectin domain of PapG from E. coli BI47 in complex with SSEA4 in space group P21 | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PapG, lectin domain, ... | 著者 | Jakob, R.P, Navarra, G, Zihlmann, P, Stangier, K, Preston, R.C, Rabbani, S, Maier, T, Ernst, B. | 登録日 | 2015-03-31 | 公開日 | 2016-04-13 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Carbohydrate-Lectin Interactions: An Unexpected Contribution to Affinity. Chembiochem, 18, 2017
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119L
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6XQW
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5DKE
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![BU of 5dke by Molmil](/molmil-images/mine/5dke) | Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-naphthyl-substituted, methyl, cis-diaryl-ethylene compound 4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol | 分子名称: | 4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-09-03 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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