6ZP8

Yeast 20S proteasome in complex with glidobactin-like natural product HB335

Summary for 6ZP8

• Entry DOI: 10.2210/pdb6zp8/pdb
• Related: 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, proteasome, inhibitor, binding analysis, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); More
• Total number of polymer chains: 28
• Total formula weight: 733222.38

Authors

Zhao, L.,Le Chapelain, C.,Brachmann, A.O.,Kaiser, M.,Groll, M.,Bode, H.B. (deposition date: 2020-07-08, release date: 2021-05-19, Last modification date: 2024-01-31)

• Primary citation: Zhao, L.,Le Chapelain, C.,Brachmann, A.O.,Kaiser, M.,Groll, M.,Bode, H.B.; Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii.; Chembiochem, 22:1582-1588, 2021; PubMed: 33452852; DOI: 10.1002/cbic.202100014

Experimental method

X-RAY DIFFRACTION (3 Å)