5SA2
 
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5SA0
 | | PanDDA analysis group deposition -- Crystal Structure of Trypanosoma brucei Trypanothione reductase in complex with Z1506050651 | | 分子名称: | (1S)-N,2,2-trimethyl-N-(pyridin-3-yl)cyclopropane-1-carboxamide, BROMIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Fiorillo, A, Ilari, A. | | 登録日 | 2021-05-18 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.
Front Mol Biosci, 9, 2022
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5S9X
 | | PanDDA analysis group deposition -- Crystal Structure of Trypanosoma brucei Trypanothione reductase in complex with Z1899842917 | | 分子名称: | 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-5-methyl-1,3,4-thiadiazol-2(3H)-one, BROMIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Fiorillo, A, Ilari, A. | | 登録日 | 2021-05-18 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.
Front Mol Biosci, 9, 2022
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5S9U
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5SA3
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5S9W
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5SA1
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5S9T
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5S9Z
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5S9Y
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5BUI
 | | ERK2 complexed with 2-pyridiyl tetrahydroazaindazole | | 分子名称: | 3-(4-fluorophenyl)-5-(pyridin-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine, Mitogen-activated protein kinase 1, NICKEL (II) ION | | 著者 | Bellamacina, C.R, Shu, W, Bussiere, D.E, Bagdanoff, J.T. | | 登録日 | 2015-06-03 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase.
Bioorg.Med.Chem.Lett., 25, 2015
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5WC7
 | | CypA Mutant - I97V S99T C115S | | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | | 著者 | Fraser, J.S. | | 登録日 | 2017-06-29 | | 公開日 | 2018-04-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
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1YEA
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5WEO
 | | Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin | | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit chimera | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | | 登録日 | 2017-07-10 | | 公開日 | 2017-08-02 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
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4IAK
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4IAY
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4XPN
 | | Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GADD34 | | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Choy, M.S, Peti, W, Page, R. | | 登録日 | 2015-01-17 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.285 Å) | | 主引用文献 | Structural and Functional Analysis of the GADD34:PP1 eIF2 alpha Phosphatase.
Cell Rep, 11, 2015
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6KAF
 | | C2S2M2N2-type PSII-LHCII | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Chang, S.H, Shen, L.L, Huang, Z.H, Wang, W.D, Han, G.Y, Shen, J.R, Zhang, X. | | 登録日 | 2019-06-22 | | 公開日 | 2019-10-23 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structure of a C2S2M2N2-type PSII-LHCII supercomplex from the green algaChlamydomonas reinhardtii.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6R0W
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1Y4J
 | | Crystal structure of the paralogue of the human formylglycine generating enzyme | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Dickmanns, A, Rudolph, M.G, Ficner, R. | | 登録日 | 2004-12-01 | | 公開日 | 2005-02-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.864 Å) | | 主引用文献 | Crystal Structure of Human pFGE, the Paralog of the C{alpha}-formylglycine-generating Enzyme
J.Biol.Chem., 280, 2005
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5WUC
 | | Structural basis for conductance through TRIC cation channels | | 分子名称: | SODIUM ION, Uncharacterized protein | | 著者 | Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2016-12-17 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
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5BUE
 | | ERK2 complexed with N-benzylpyridone tetrahydroazaindazole | | 分子名称: | 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1H)-one, Mitogen-activated protein kinase 1, NICKEL (II) ION | | 著者 | Bellamacina, C.R, Shu, W, Bussiere, D.E, Bagdanoff, J.T. | | 登録日 | 2015-06-03 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase.
Bioorg.Med.Chem.Lett., 25, 2015
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4IAF
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5WEL
 | | GluA2 bound to antagonist ZK and GSG1L in digitonin, state 2 | | 分子名称: | Chimera of Glutamate receptor 2, Germ cell-specific gene 1-like protein, Digitonin, ... | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | | 登録日 | 2017-07-10 | | 公開日 | 2017-08-02 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
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3BTS
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