PDB: 236963 件ウェブページステータス検索Chemie searchBIRD

---

6E1H	Structure of 2:1 human Ptch1-Shh-N complex 分子名称: CALCIUM ION, PALMITIC ACID, Protein patched homolog 1, ... 著者 Qi, X, Li, X. 登録日 2018-07-09 公開日 2018-08-29 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex. Science, 362, 2018
6E1I	HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET 分子名称: HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET 著者 Finton, K.A.K, Rusnac, D.V. 登録日 2018-07-09 公開日 2019-07-17 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Effects of HLA single chain trimer design on peptide presentation and stability To Be Published
6E1J	Crystal Structure of Methylthioalkylmalate Synthase (BjuMAM1.1) from Brassica juncea 分子名称: 2-isopropylmalate synthase, A genome specific 1, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, ... 著者 Lee, S.G, Jez, J.M. 登録日 2018-07-09 公開日 2019-05-08 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Molecular Basis of the Evolution of Methylthioalkylmalate Synthase and the Diversity of Methionine-Derived Glucosinolates. Plant Cell, 31, 2019
6E1K	Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab 分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... 著者 Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. 登録日 2018-07-10 公開日 2018-09-19 最終更新日 2024-12-25 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1L	GRN3Ala 分子名称: Granulin 著者 Dastpeyman, M, Bansal, P, Wilson, D, Sotillo, J, Brindley, P, Loukas, A, Smout, M, Daly, N. 登録日 2018-07-10 公開日 2019-02-06 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing. J. Med. Chem., 61, 2018
6E1M	Structure of AtTPC1(DDE) reconstituted in saposin A 分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... 著者 Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. 登録日 2018-07-10 公開日 2018-09-19 最終更新日 2024-12-25 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1N	Structure of AtTPC1(DDE) in state 1 分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... 著者 Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. 登録日 2018-07-10 公開日 2018-09-19 最終更新日 2024-12-25 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1O	afTMEM16 reconstituted in nanodiscs in the presence of Ca2+ and ceramide 24:0 分子名称: CALCIUM ION, DECANE, DODECANE, ... 著者 Falzone, M.E, Accardi, A. 登録日 2018-07-10 公開日 2019-02-06 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase. Elife, 8, 2019
6E1P	Structure of AtTPC1(DDE) in state 2 分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1 著者 Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. 登録日 2018-07-10 公開日 2018-09-19 最終更新日 2024-12-25 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1Q	AtGH3.15 acyl acid amido synthetase in complex with 2,4-DB 分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, AtGH3.15 acyl acid amido synthetase, PHOSPHATE ION 著者 Sharp, A.M, Lee, S.G, Jez, J.M. 登録日 2018-07-10 公開日 2018-10-24 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.148 Å) 主引用文献 Modification of auxinic phenoxyalkanoic acid herbicides by the acyl acid amido synthetase GH3.15 from Arabidopsis. J. Biol. Chem., 293, 2018
6E1R	Crystal structure of the Acinetobacter phage vB_ApiP_P1 tailspike protein 分子名称: CHLORIDE ION, SODIUM ION, Tailspike protein 著者 Plattner, M, Shneider, M.M, Oliveira, H, Azeredo, J, Leiman, P.G. 登録日 2018-07-10 公開日 2019-07-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.693 Å) 主引用文献 Crystal structure of the Acinetobacter phage vB_ApiP_P1 tailspike protein To Be Published
6E1S	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1T	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1U	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 2: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine, MAGNESIUM ION, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1V	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 3: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1W	Crystal structure of a class I PreQ1 riboswitch complexed with PreQ1 分子名称: 2-amino-5-(aminomethyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ACETATE ION, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1X	Crystal structure of product-bound complex of spermidine/spermine N-acetyltransferase SpeG 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-07-10 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of product-bound complex of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae. To Be Published
6E1Y	Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design 分子名称: N-[(1S)-1-(3-chlorophenyl)ethyl]-3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}benzamide, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.219 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E1Z	Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity 分子名称: 5-[(1H-imidazol-1-yl)methyl]furan-2-carboxylic acid, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E20	Crystal structure of the Dario rerio galectin-1-L2 分子名称: Galectin, MAGNESIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose 著者 Ghosh, A, Bianchet, M.A. 登録日 2018-07-10 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the zebrafish galectin-1-L2 and model of its interaction with the infectious hematopoietic necrosis virus (IHNV) envelope glycoprotein. Glycobiology, 29, 2019
6E21	Joint X-ray/neutron structure of PKAc with products Sr2-ADP and phosphorylated peptide SP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A, Gerlits, O.O, Taylor, S. 登録日 2018-07-10 公開日 2019-04-03 最終更新日 2024-11-06 実験手法 NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION 主引用文献 Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex. Sci Adv, 5, 2019
6E22	Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity 分子名称: 3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}-N-[(3,5-dimethoxyphenyl)methyl]-4-fluorobenzamide, SULFATE ION, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E23	Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(3,4-dichlorophenyl)methyl]-3-(6-fluoro-2-methylpyridin-3-yl)-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}benzamide, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E24	Ternary structure of c-Myc-TBP-TAF1 分子名称: Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein 著者 Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2018-07-10 公開日 2019-10-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Multiple direct interactions of TBP with the MYC oncoprotein. Nat.Struct.Mol.Biol., 26, 2019
6E25	NMR solution structure of the CARD9 CARD bound to zinc 分子名称: Caspase recruitment domain-containing protein 9, ZINC ION 著者 Holliday, M.J, Dueber, E.C, Fairbrother, W.J. 登録日 2018-07-10 公開日 2018-09-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293, 2018

<5918591959205921592259235924592559265927592859295930593159325933>