8WY1
 
 | | The structure of cyclization domain in cyclic beta-1,2-glucan synthase from Thermoanaerobacter italicus | | 分子名称: | Glycosyltransferase 36 | | 著者 | Tanaka, N, Saito, R, Kobayashi, K, Nakai, H, Kamo, S, Kuramochi, K, Taguchi, H, Nakajima, M, Masaike, T. | | 登録日 | 2023-10-30 | | 公開日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Functional and structural analysis of a cyclization domain in a cyclic beta-1,2-glucan synthase.
Appl.Microbiol.Biotechnol., 108, 2024
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7N00
 | | Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha | | 分子名称: | ALK and LTK ligand 2, ALK tyrosine kinase receptor | | 著者 | Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G. | | 登録日 | 2021-05-24 | | 公開日 | 2021-11-24 | | 最終更新日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
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7MZY
 | | Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986 | | 分子名称: | ACETATE ION, ALK tyrosine kinase receptor | | 著者 | Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G. | | 登録日 | 2021-05-24 | | 公開日 | 2021-11-24 | | 最終更新日 | 2021-12-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
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3SWN
 | | Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings | | 分子名称: | U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, ... | | 著者 | Mund, M, Neu, A, Ullmann, J.L, Neu, U, Sprangers, R. | | 登録日 | 2011-07-14 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings.
J.Mol.Biol., 414, 2011
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8AAZ
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8AIF
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3RY8
 | | Structural basis for norovirus inhibition and fucose mimicry by citrate | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Capsid protein | | 著者 | Hansman, G.S, McLellan, J.S, Kwong, P.D. | | 登録日 | 2011-05-11 | | 公開日 | 2011-11-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for norovirus inhibition and fucose mimicry by citrate.
J.Virol., 86, 2012
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1BTO
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7PNJ
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7PNR
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6DN5
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6DF5
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | 著者 | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | 登録日 | 2018-05-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | | 主引用文献 | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DFB
 | | Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | 著者 | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | 登録日 | 2018-05-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DFC
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) with a T-to-U substitution | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*AP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*UP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | 著者 | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | 登録日 | 2018-05-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DGQ
 | | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10506 | | 分子名称: | N-(2-{4-[(2,4-dioxo-3,4-dihydro-2H-1lambda~4~,3-thiazol-5-yl)methyl]phenoxy}ethyl)-5-[(3R)-1,2-dithiolan-3-yl]pentanamide, Peroxisome proliferator-activated receptor gamma | | 著者 | Shang, J, Kojetin, D.J. | | 登録日 | 2018-05-17 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6DJA
 | | ZN-DEPENDENT 5/B/6 METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS | | 分子名称: | Metallo-beta-lactamase type 2, ZINC ION | | 著者 | Bui, A.A, Khan, N.H, Shaw, R.W, Sutton, R.B. | | 登録日 | 2018-05-24 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | A DNA aptamer reveals an allosteric site for inhibition in metallo-beta-lactamases.
Plos One, 14, 2019
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6DN8
 | | SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor | | 分子名称: | (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ... | | 著者 | Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. | | 登録日 | 2018-06-06 | | 公開日 | 2019-04-17 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
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6DKY
 | | Crystal structure of ribifolin, an orbitide from Jatropha ribifolia | | 分子名称: | ILE-LEU-GLY-SER-ILE-ILE-LEU-GLY | | 著者 | Wang, C.K, Ramalho, S.D, King, G.J, Craik, D.J. | | 登録日 | 2018-05-31 | | 公開日 | 2018-11-07 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (1.239 Å) | | 主引用文献 | Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species.
J. Nat. Prod., 81, 2018
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6DLH
 | | Endo-fucoidan hydrolase MfFcnA4 from glycoside hydrolase family 107 | | 分子名称: | 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION, ... | | 著者 | Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B. | | 登録日 | 2018-06-01 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
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6DNY
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6E4Y
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6E4Z
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6E27
 | | The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites | | 分子名称: | Caspase recruitment domain-containing protein 9, ZINC ION | | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.
J. Biol. Chem., 293, 2018
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6E28
 | | The CARD9 CARD domain-swapped dimer | | 分子名称: | Caspase recruitment domain-containing protein 9 | | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.
J. Biol. Chem., 293, 2018
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6E21
 | | Joint X-ray/neutron structure of PKAc with products Sr2-ADP and phosphorylated peptide SP20 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Kovalevsky, A, Gerlits, O.O, Taylor, S. | | 登録日 | 2018-07-10 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | | 主引用文献 | Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex.
Sci Adv, 5, 2019
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