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7E1C
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Structure of MreB3 from Spiroplasma eriocheiris
分子名称: ACETATE ION, CALCIUM ION, Cell shape-determining protein MreB
著者Takahashi, D, Miyata, M, Imada, K.
登録日2021-02-01
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming.
Open Biology, 12, 2022
2L4S
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BU of 2l4s by Molmil
Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L
分子名称: Tax1-binding protein 3
著者Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S.
登録日2010-10-13
公開日2011-04-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
2L4T
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BU of 2l4t by Molmil
GIP/Glutaminase L peptide complex
分子名称: Glutaminase L peptide, Tax1-binding protein 3
著者Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S.
登録日2010-10-13
公開日2011-04-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
2KXC
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BU of 2kxc by Molmil
1H, 13C, and 15N Chemical Shift Assignments for IRTKS-SH3 and EspFu-R47 complex
分子名称: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, EspF-like protein
著者Aitio, O, Hellman, M, Kazlauskas, A, Vingadassalom, D.F, Leong, J.M, Saksela, K, Permi, P.
登録日2010-04-30
公開日2010-11-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly
Proc.Natl.Acad.Sci.USA, 107, 2010
2DAT
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BU of 2dat by Molmil
Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin dependent regulator of cromatin subfamily A member 2
分子名称: Possible global transcription activator SNF2L2
著者Yoneyama, M, Kigawa, T, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2007-01-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin dependent regulator of cromatin subfamily A member 2
To be Published
1XI0
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BU of 1xi0 by Molmil
X-ray crystal structure of wild-type Xerocomus chrysenteron lectin XCL
分子名称: lectin
著者Birck, C, Damian, L, Marty-Detraves, C, Lougarre, A, Schulze-Briese, C, Koehl, P, Fournier, D, Paquereau, L, Samama, J.P.
登録日2004-09-21
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A new lectin family with structure similarity to actinoporins revealed by the crystal structure of Xerocomus chrysenteron lectin XCL
J.Mol.Biol., 344, 2004
7O7J
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BU of 7o7j by Molmil
Crystal structure of the human HIPK3 kinase domain bound to abemaciclib
分子名称: Homeodomain-interacting protein kinase 3, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine
著者Kaltheuner, I.H, Anand, K, Geyer, M.
登録日2021-04-13
公開日2021-11-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.
Nat Commun, 12, 2021
4U7I
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BU of 4u7i by Molmil
Structure of the complex of Spartin MIT and IST1 MIM
分子名称: IST1 homolog, Spartin
著者Guo, E.Z, Xu, Z.
登録日2014-07-30
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
6NBF
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BU of 6nbf by Molmil
Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein
分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y.
登録日2018-12-07
公開日2019-04-17
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
3CM1
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BU of 3cm1 by Molmil
Crystal structure of SsgA-like sporulation-specific cell division protein (YP_290167.1) from Thermobifida fusca YX-ER1 at 2.60 A resolution
分子名称: SsgA-like sporulation-specific cell division protein
著者Joint Center for Structural Genomics (JCSG), Chruszcz, M, Minor, W, Wang, S.
登録日2008-03-20
公開日2008-04-01
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
J.Biol.Chem., 284, 2009
3CWZ
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BU of 3cwz by Molmil
Structure of RAB6(GTP)-R6IP1 complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ...
著者Recacha, R, Houdusse, A, Goud, B, Khan, A.R.
登録日2008-04-23
公開日2008-11-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.
Structure, 17, 2009
6OCQ
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BU of 6ocq by Molmil
Crystal structure of RIP1 kinase in complex with a pyrrolidine
分子名称: 1-[(2S)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one, Receptor-interacting serine/threonine-protein kinase 1, SULFATE ION
著者Thorpe, J.H, Harris, P.A.
登録日2019-03-25
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J.Med.Chem., 62, 2019
7LOI
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BU of 7loi by Molmil
Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail
分子名称: Transmembrane protein gp41
著者Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J.
登録日2021-02-10
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology.
J.Am.Chem.Soc., 143, 2021
2FMU
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BU of 2fmu by Molmil
Crystal structure of a tat-interacting protein homologue (htatip2, aw111545, cc3, tip30) from mus musculus at 2.30 A resolution
分子名称: 1,2-ETHANEDIOL, HIV-1 tat interactive protein 2, 30 kDa homolog
著者Joint Center for Structural Genomics (JCSG)
登録日2006-01-09
公開日2006-02-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Tat-interacting protein 30 kDa (HIV-1 tat interactive protein 2, 30 kDa Homolog) (Human) (16924205) from Mus musculus at 2.30 A resolution
To be published
3MS6
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BU of 3ms6 by Molmil
Crystal structure of Hepatitis B X-Interacting Protein (HBXIP)
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Hepatitis B virus X-interacting protein, ...
著者Garcia-Saez, I, Skoufias, D.
登録日2010-04-29
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.085 Å)
主引用文献Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx.
J.Mol.Biol., 405, 2011
4L0R
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BU of 4l0r by Molmil
Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.
分子名称: Centrosomal protein of 57 kDa
著者Seetharaman, J, Lew, S, Su, M, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2013-05-31
公開日2013-09-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics consortium id HR9027A
To be Published
1WIM
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BU of 1wim by Molmil
Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4
分子名称: KIAA0161 protein, ZINC ION
著者Miyamoto, K, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4
To be Published
1X5M
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BU of 1x5m by Molmil
Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)
分子名称: Calcyclin-binding protein
著者Qin, X.R, Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-16
公開日2005-11-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)
To be published
7X6R
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BU of 7x6r by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCACGT/ACGGGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, Actinomycin D, COBALT (II) ION, ...
著者Kao, S.H, Satange, R.B, Hou, M.H.
登録日2022-03-08
公開日2022-12-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7X97
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BU of 7x97 by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCCCGT/ACGGGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, Actinomycin D, CHLORIDE ION, ...
著者Kao, S.H, Satange, R.B, Hou, M.H.
登録日2022-03-15
公開日2022-12-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
5DZ6
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BU of 5dz6 by Molmil
Acyl transferase from Bacillaene PKS
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Till, M, Race, P.R.
登録日2015-09-25
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-acyltransferase polyketide synthases
To Be Published
4NIQ
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BU of 4niq by Molmil
Crystal Structure of Vps4 MIT-Vfa1 MIM2
分子名称: VPS4-associated protein 1, Vacuolar protein sorting-associated protein 4
著者Vild, C.J, Xu, Z.
登録日2013-11-06
公開日2014-03-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Vfa1 Binds to the N-terminal Microtubule-interacting and Trafficking (MIT) Domain of Vps4 and Stimulates Its ATPase Activity.
J.Biol.Chem., 289, 2014
6SVL
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BU of 6svl by Molmil
human Myeloid-derived growth factor (MYDGF) in complex with neutralizing Fab
分子名称: Fab_heavy_chain, Fab_light_chain, GLYCEROL, ...
著者Ebenhoch, R, Nar, H.
登録日2019-09-18
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure and receptor-interacting residues of MYDGF - a protein mediating ischemic tissue repair.
Nat Commun, 10, 2019
6SVK
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human Myeloid-derived growth factor (MYDGF)
分子名称: MALONATE ION, Myeloid-derived growth factor
著者Ebenhoch, R, Nar, H.
登録日2019-09-18
公開日2019-11-27
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献Crystal structure and receptor-interacting residues of MYDGF - a protein mediating ischemic tissue repair.
Nat Commun, 10, 2019
2RGU
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BU of 2rgu by Molmil
Crystal structure of complex of human DPP4 and inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-d ione, Dipeptidyl peptidase 4
著者Nar, H, Himmelsbach, F, Eckhardt, M.
登録日2007-10-05
公開日2007-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.
J.Med.Chem., 50, 2007

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