8SP8
| Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHLORIDE ION, ... | 著者 | Neuberger, A, Yelshanskaya, M.V, Nadezhdin, K.D, Sobolevsky, A.I. | 登録日 | 2023-05-02 | 公開日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. Nat Commun, 14, 2023
|
|
8SPD
| Cytochrome P450 (CYP) 3A4 crystallized with clotrimazole | 分子名称: | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hsu, M.H, Johnson, E.F. | 登録日 | 2023-05-02 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochromes P450 3A5 and 3A4. Drug Metab.Dispos., 51, 2023
|
|
8SPC
| |
8SOV
| Proteinase K Multiconformer Model at 353K | 分子名称: | ALA-ALA-ALA-SER-VAL-LYS, CALCIUM ION, Proteinase K, ... | 著者 | Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. | 登録日 | 2023-04-30 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.291 Å) | 主引用文献 | Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
|
|
8SOU
| Proteinase K Multiconformer Model at 363K | 分子名称: | ALA-ALA-ALA-SER-VAL-LYS, CALCIUM ION, Proteinase K, ... | 著者 | Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. | 登録日 | 2023-04-30 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
|
|
8SOR
| Structure of human PI3KC3-C1 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beclin 1-associated autophagy-related key regulator, Beclin-1, ... | 著者 | Chen, M, Hurley, J.H. | 登録日 | 2023-04-29 | 公開日 | 2023-06-21 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv, 2023
|
|
8SO2
| Human CYP3A4 bound to a substrate | 分子名称: | CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sevrioukova, I.F. | 登録日 | 2023-04-28 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299, 2023
|
|
8SO1
| Human CYP3A4 bound to three caffeine molecules | 分子名称: | CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sevrioukova, I.F. | 登録日 | 2023-04-28 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299, 2023
|
|
8SOG
| Proteinase K Multiconformer Model at 313K | 分子名称: | CALCIUM ION, Proteinase K, SULFATE ION | 著者 | Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. | 登録日 | 2023-04-28 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
|
|
7G1E
| Crystal Structure of human FABP4 in complex with 3-[(2-phenylphenoxy)methyl]benzoic acid | 分子名称: | 3-{[([1,1'-biphenyl]-2-yl)oxy]methyl}benzoic acid, Fatty acid-binding protein, adipocyte, ... | 著者 | Ehler, A, Benz, J, Obst, U, Gillespie, P, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7G16
| Crystal Structure of human FABP4 in complex with 6-bromo-3-hexyl-2-oxo-3,4-dihydro-1H-quinoline-4-carboxylic acid | 分子名称: | (3S,4R)-6-bromo-3-hexyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid, BROMIDE ION, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Hofheinz, W, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FW8
| Crystal Structure of human FABP4 binding site mutated to that of FABP3 in complex with 6-chloro-2-methyl-4-phenylquinoline-3-carboxylic acid | 分子名称: | 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Crystal Structure of a human FABP4 binding site mutated to that of FABP3 complex To be published
|
|
7G1D
| Crystal Structure of human FABP4 in complex with 5-ethyl-6-(3-methoxyphenyl)-3-methyl-2-sulfanylidene-1H-pyrimidin-4-one | 分子名称: | (6M)-5-ethyl-6-(3-methoxyphenyl)-3-methyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | 著者 | Ehler, A, Benz, J, Obst, U, Wichmann, J, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FWI
| Crystal Structure of human FABP5 in complex with 2-(indole-1-carbonylamino)benzoic acid | 分子名称: | 2-[(2,3-dihydro-1H-indole-1-carbonyl)amino]benzoic acid, CHLORIDE ION, Fatty acid-binding protein 5 | 著者 | Ehler, A, Benz, J, Obst, U, Ning, R, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a human FABP5 complex To be published
|
|
7FZ2
| Crystal Structure of human FABP4 in complex with [3-oxo-5-[4-(trifluoromethyl)phenyl]cyclohexen-1-yl] acetate | 分子名称: | (1S)-5-hydroxy-4'-(trifluoromethyl)-1,6-dihydro[1,1'-biphenyl]-3(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | 著者 | Ehler, A, Benz, J, Obst, U, Kumagai, Y, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FWR
| Crystal Structure of human FABP4 in complex with 3-[(3,4-dichlorophenyl)methylsulfanyl]-1,2,4-triazin-5-ol | 分子名称: | 3-{[(3,4-dichlorophenyl)methyl]sulfanyl}-1,2,4-triazin-5-ol, Fatty acid-binding protein, adipocyte, ... | 著者 | Ehler, A, Benz, J, Obst, U, Montavon, M, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FX5
| Crystal Structure of human FABP4 in complex with 5-[[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6,6-difluoro-5,7-dihydro-4H-1-benzothiophen-2-yl]carbamoyl]-3,6-dihydro-2H-pyran-4-carboxylic acid | 分子名称: | 5-{[(3M)-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-6,6-difluoro-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}-3,6-dihydro-2H-pyran-4-carboxylic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Ehler, A, Benz, J, Obst, U, Richter, H, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7G12
| Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-propan-2-yl-3-(1H-tetrazol-5-yl)pyridin-2-amine | 分子名称: | (3M,6P)-N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-(propan-2-yl)-3-(1H-tetrazol-5-yl)pyridin-2-amine, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Kuhne, H, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal Structure of a human FABP4 binding site mutated to that of FABP5 complex To be published
|
|
7FWQ
| Crystal Structure of human FABP4 binding site mutated to that of FABP3 in complex with 6-chloro-4-(2-chlorophenoxy)-2-methylquinoline-3-carboxylic acid | 分子名称: | 6-chloro-4-(2-chlorophenoxy)-2-methylquinoline-3-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Conte, A, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal Structure of a human FABP4 binding site mutated to that of FABP3 complex To be published
|
|
7G1G
| Crystal Structure of human FABP4 in complex with 2-(2-hydroxy-3,5,5,8,8-pentamethyl-3,4,4a,6,7,8a-hexahydro-1H-naphthalen-2-yl)acetic acid | 分子名称: | FORMIC ACID, Fatty acid-binding protein, adipocyte, ... | 著者 | Ehler, A, Benz, J, Obst, U, Hochstetler-A, D, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FYS
| Crystal Structure of human FABP4 in complex with 7-(4-methoxyphenyl)-1,8-dithia-3-azaspiro[4.5]dec-6-ene-2,4-dione | 分子名称: | (5R)-7-(4-hydroxyphenyl)-1,8-dithia-3-azaspiro[4.5]dec-6-ene-2,4-dione, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Widmer, U, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7G20
| Crystal Structure of human FABP4 in complex with 1-[(4-methoxyphenyl)methyl]-5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | 分子名称: | (5S)-1-[(4-methoxyphenyl)methyl]-5-(propan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione, 1,2-ETHANEDIOL, FORMIC ACID, ... | 著者 | Ehler, A, Benz, J, Obst, U, Schnider, O, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FWO
| Crystal Structure of human FABP4 in complex with 2-cyclohexyl-6-hydroxy-1-benzofuran-3-one | 分子名称: | (2S)-2-cyclohexyl-6-hydroxy-1-benzofuran-3(2H)-one, FORMIC ACID, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Boehringer, M, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FW2
| Crystal Structure of human FABP4 in complex with 5-[(4-chlorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazole-3-thiol | 分子名称: | 5-[(4-chlorophenoxy)methyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazole-3-thiol, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ... | 著者 | Ehler, A, Benz, J, Obst, U, Brunner, M, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|
7FX6
| Crystal Structure of human FABP4 in complex with N,N-diethyl-4-pyridin-4-yl-3-(1H-tetrazol-5-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-amine | 分子名称: | (3M)-N,N-diethyl-4-(pyridin-4-yl)-3-(1H-tetrazol-5-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-amine, Fatty acid-binding protein, adipocyte, ... | 著者 | Ehler, A, Benz, J, Obst, U, Obst-Sander, U, Rudolph, M.G. | 登録日 | 2023-04-27 | 公開日 | 2023-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Crystal Structure of a human FABP4 complex To be published
|
|