2P5W
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![BU of 2p5w by Molmil](/molmil-images/mine/2p5w) | Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, CALCIUM ION, ... | 著者 | Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K. | 登録日 | 2007-03-16 | 公開日 | 2007-09-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of high affinity human T-cell receptors bound to peptide major
histocompatibility complex reveal native diagonal binding geometry Protein Eng.Des.Sel., 20, 2007
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8ERX
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![BU of 8erx by Molmil](/molmil-images/mine/8erx) | Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide | 分子名称: | Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-13 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
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1EEZ
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![BU of 1eez by Molmil](/molmil-images/mine/1eez) | |
8ESH
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![BU of 8esh by Molmil](/molmil-images/mine/8esh) | Structure of chimeric HLA-A*02:01 bound to CMV peptide | 分子名称: | Beta-2-microglobulin, CMV peptide, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-14 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
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1EXU
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![BU of 1exu by Molmil](/molmil-images/mine/1exu) | CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR | 分子名称: | BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51 | 著者 | West Jr, A.P, Bjorkman, P.J. | 登録日 | 2000-05-04 | 公開日 | 2000-08-10 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,). Biochemistry, 39, 2000
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8ES9
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![BU of 8es9 by Molmil](/molmil-images/mine/8es9) | |
8ES8
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![BU of 8es8 by Molmil](/molmil-images/mine/8es8) | |
7N6E
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![BU of 7n6e by Molmil](/molmil-images/mine/7n6e) | TCR peptide HLA-A2 complex | 分子名称: | Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ... | 著者 | Chaurasia, P, Rossjohn, J, Petersen, J. | 登録日 | 2021-06-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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7N1A
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![BU of 7n1a by Molmil](/molmil-images/mine/7n1a) | SARS-CoV-2 YLQ peptide binds to HLA-A2 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.065 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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7N1B
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![BU of 7n1b by Molmil](/molmil-images/mine/7n1b) | SARS-CoV-2 RLQ peptide binds to HLA-A2 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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7N6D
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![BU of 7n6d by Molmil](/molmil-images/mine/7n6d) | HLA peptide complex | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Chaurasia, P, Petersen, J, Rossjohn, J. | 登録日 | 2021-06-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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8ELH
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![BU of 8elh by Molmil](/molmil-images/mine/8elh) | |
8ELG
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![BU of 8elg by Molmil](/molmil-images/mine/8elg) | |
7N1F
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![BU of 7n1f by Molmil](/molmil-images/mine/7n1f) | |
7N1E
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![BU of 7n1e by Molmil](/molmil-images/mine/7n1e) | |
2RFX
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![BU of 2rfx by Molmil](/molmil-images/mine/2rfx) | Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. | 登録日 | 2007-10-02 | 公開日 | 2008-07-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28, 2008
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8EK5
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![BU of 8ek5 by Molmil](/molmil-images/mine/8ek5) | Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | 分子名称: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | 著者 | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | 登録日 | 2022-09-20 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
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7NDT
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![BU of 7ndt by Molmil](/molmil-images/mine/7ndt) | |
7NDU
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![BU of 7ndu by Molmil](/molmil-images/mine/7ndu) | |
7NDQ
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![BU of 7ndq by Molmil](/molmil-images/mine/7ndq) | Gag:02 TCR in complex with HLA-E. | 分子名称: | Beta-2-microglobulin, Gag6V, HLA class I histocompatibility antigen, ... | 著者 | Pengelly, R.J, Robinson, R.A. | 登録日 | 2021-02-02 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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8EMF
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![BU of 8emf by Molmil](/molmil-images/mine/8emf) | |
8EN8
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![BU of 8en8 by Molmil](/molmil-images/mine/8en8) | |
8EMG
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![BU of 8emg by Molmil](/molmil-images/mine/8emg) | |
8ENH
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![BU of 8enh by Molmil](/molmil-images/mine/8enh) | |
8EO8
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![BU of 8eo8 by Molmil](/molmil-images/mine/8eo8) | |