PDB: 6519 件ウェブページステータス検索Chemie searchBIRD

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2P5W	Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, CALCIUM ION, ... 著者 Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K. 登録日 2007-03-16 公開日 2007-09-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry Protein Eng.Des.Sel., 20, 2007
8ERX	Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide 分子名称: Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01 著者 Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. 登録日 2022-10-13 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
1EEZ	Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L) 分子名称: BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, HLA-A2.1 MHC CLASS I (HEAVY CHAIN) 著者 Sharma, A.K, Kuhns, J.J, Collins, E.J. 登録日 2000-02-04 公開日 2003-06-10 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts. J.Biol.Chem., 276, 2001
8ESH	Structure of chimeric HLA-A*02:01 bound to CMV peptide 分子名称: Beta-2-microglobulin, CMV peptide, HLA-A*02:01 著者 Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. 登録日 2022-10-14 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
1EXU	CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR 分子名称: BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51 著者 West Jr, A.P, Bjorkman, P.J. 登録日 2000-05-04 公開日 2000-08-10 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,). Biochemistry, 39, 2000
8ES9	CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... 著者 Saotome, K, Franklin, M.C. 登録日 2022-10-13 公開日 2023-05-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ES8	CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... 著者 Saotome, K, Franklin, M.C. 登録日 2022-10-13 公開日 2023-05-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
7N6E	TCR peptide HLA-A2 complex 分子名称: Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ... 著者 Chaurasia, P, Rossjohn, J, Petersen, J. 登録日 2021-06-08 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
7N1A	SARS-CoV-2 YLQ peptide binds to HLA-A2 分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2021-05-27 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.065 Å) 主引用文献 Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
7N1B	SARS-CoV-2 RLQ peptide binds to HLA-A2 分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2021-05-27 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
7N6D	HLA peptide complex 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... 著者 Chaurasia, P, Petersen, J, Rossjohn, J. 登録日 2021-06-08 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
8ELH	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus 分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... 著者 Murdolo, L.D, Gras, S. 登録日 2022-09-24 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
8ELG	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANAF from OC43 virus 分子名称: ACETATE ION, Beta-2-microglobulin, NQK-OC43 peptide, ... 著者 Murdolo, L.D, Gras, S. 登録日 2022-09-24 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
7N1F	SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 binds to YLQ-HLA-A2 分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2021-05-27 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
7N1E	SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 binds to RLQ-HLA-A2 分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2021-05-27 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
2RFX	Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. 登録日 2007-10-02 公開日 2008-07-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28, 2008
8EK5	Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 分子名称: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... 著者 Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. 登録日 2022-09-20 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
7NDT	UL40:01 TCR in complex with HLA-E with a non-natural amino acid 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... 著者 Pengelly, R.J, Robinson, R.A. 登録日 2021-02-02 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
7NDU	Gag:02 TCR in complex with HLA-E featuring a non-natural amino acid 分子名称: Beta-2-microglobulin, Gag6V(276-284 H4C), HLA class I histocompatibility antigen, ... 著者 Pengelly, R.J, Robinson, R.A. 登録日 2021-02-02 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
7NDQ	Gag:02 TCR in complex with HLA-E. 分子名称: Beta-2-microglobulin, Gag6V, HLA class I histocompatibility antigen, ... 著者 Pengelly, R.J, Robinson, R.A. 登録日 2021-02-02 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.551 Å) 主引用文献 Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
8EMF	Crystal structure of a HLA-B*35:01-NP6 epitope from 1977 H1N1 influenza strain 分子名称: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP6 epitope 著者 Littler, D.R, Rossjohn, J. 登録日 2022-09-27 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.80482423 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EN8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain 分子名称: 3180 TCR alpha chain, 3180 TCR beta chain, Beta-2-microglobulin, ... 著者 Littler, D.R, Rossjohn, J. 登録日 2022-09-29 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.700012 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMG	Crystal structure of a HLA-B*35:01-NP7 epitope from 2002 H2N1 influenza strain 分子名称: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... 著者 Littler, D.R, Rossjohn, J. 登録日 2022-09-27 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.83001268 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8ENH	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain 分子名称: 3180 TCR alpha chain, Beta-2-microglobulin, MHC class I antigen, ... 著者 Littler, D.R, Rossjohn, J. 登録日 2022-09-30 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.500032 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EO8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain 分子名称: 3180 alpha chain, 3180 beta chain, Beta-2-microglobulin, ... 著者 Littler, D.R, Rossjohn, J. 登録日 2022-10-02 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.300001 Å) 主引用文献 Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published

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