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1LT8
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Reduced Homo sapiens Betaine-Homocysteine S-Methyltransferase in Complex with S-(delta-carboxybutyl)-L-Homocysteine
分子名称: BETAINE-HOMOCYSTEINE METHYLTRANSFERASE, CITRIC ACID, S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE, ...
著者Evans, J.C, Huddler, D.P, Jiracek, J, Castro, C, Millian, N.S, Garrow, T.A, Ludwig, M.L.
登録日2002-05-20
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Betaine-homocysteine methyltransferase: zinc in a distorted barrel.
Structure, 10, 2002
1LOR
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BU of 1lor by Molmil
crystal structure of orotidine 5'-monophosphate complexed with BMP
分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, orotidine monophosphate decarboxylase
著者Wu, N, Pai, E.F.
登録日2002-05-06
公開日2002-08-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J.Biol.Chem., 277, 2002
1VQ9
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The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1HKV
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mycobacterium diaminopimelate dicarboxylase (lysa)
分子名称: DIAMINOPIMELATE DECARBOXYLASE, LYSINE, PYRIDOXAL-5'-PHOSPHATE
著者Gokulan, K, Rupp, B, Pavelka Jr, M.S, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2003-03-11
公開日2003-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Mycobacterium Tuberculosis Diaminopimelate Decarboxylase, an Essential Enzyme in Bacterial Lysine Biosynthesis
J.Biol.Chem., 278, 2003
1T31
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A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S.
登録日2004-04-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
1T3W
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BU of 1t3w by Molmil
Crystal Structure of the E.coli DnaG C-terminal domain (residues 434 to 581)
分子名称: ACETIC ACID, DNA primase
著者Oakley, A.J, Loscha, K.V, Schaeffer, P.M, Liepinsh, E, Wilce, M.C.J, Otting, G, Dixon, N.E.
登録日2004-04-28
公開日2004-11-02
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal and solution structures of the helicase-binding domain of Escherichia coli primase
J.Biol.Chem., 280, 2005
1T6N
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BU of 1t6n by Molmil
Crystal structure of the N-terminal domain of human UAP56
分子名称: CITRATE ANION, Probable ATP-dependent RNA helicase
著者Zhao, R.
登録日2004-05-06
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export
Structure, 12, 2004
1T9E
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NMR solution structure of a disulfide analogue of the cyclic sunflower trypsin inhibitor SFTI-1
分子名称: Trypsin inhibitor 1
著者Korsinczky, M.L.J, Clark, R.J, Craik, D.J.
登録日2004-05-16
公開日2005-05-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1
Biochemistry, 44, 2005
1SUO
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BU of 1suo by Molmil
Structure of mammalian cytochrome P450 2B4 with bound 4-(4-chlorophenyl)imidazole
分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Scott, E.E, White, M.A, He, Y.A, Johnson, E.F, Stout, C.D, Halpert, J.R.
登録日2004-03-26
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9 {angstrom} resolution: Insight into the range of P450 conformations and coordination of redox partner binding.
J.Biol.Chem., 279, 2004
1T0N
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Conformational switch in polymorphic H-2K molecules containing an HSV peptide
分子名称: Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ...
著者Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J.
登録日2004-04-12
公開日2004-11-23
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.
J Immunol., 173, 2004
1IO9
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BU of 1io9 by Molmil
THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES
分子名称: CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE
著者Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2001-02-08
公開日2001-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
J.Inorg.Biochem., 91, 2002
1JHT
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BU of 1jht by Molmil
Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (ALGIGILTV) from the MART-1/Melan-A.
分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, ...
著者Sliz, P, Michielin, O, Karplus, M, Romero, P, Wiley, D.
登録日2001-06-28
公開日2001-09-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.
J.Immunol., 167, 2001
1K28
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BU of 1k28 by Molmil
The Structure of the Bacteriophage T4 Cell-Puncturing Device
分子名称: BASEPLATE STRUCTURAL PROTEIN GP27, PHOSPHATE ION, POTASSIUM ION, ...
著者Kanamaru, S, Leiman, P.G, Kostyuchenko, V.A, Chipman, P.R, Mesyanzhinov, V.V, Arisaka, F, Rossmann, M.G.
登録日2001-09-26
公開日2002-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the cell-puncturing device of bacteriophage T4.
Nature, 415, 2002
1T9Q
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Crystal Structure of V44L Cp Rubredoxin
分子名称: FE (III) ION, Rubredoxin
著者Park, I.Y, Eidsness, M.K, Lin, I.J, Gebel, E.B, Youn, B, Harley, J.L, Machonkin, T.E, Frederick, R.O, Markley, J.L, Smith, E.T, Ichiye, T, Kang, C.
登録日2004-05-18
公開日2004-10-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies of V44 mutants of Clostridium pasteurianum rubredoxin: Effects of side-chain size on reduction potential.
Proteins, 57, 2004
1VQL
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The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1W2B
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Trigger Factor ribosome binding domain in complex with 50S
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ...
著者Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
登録日2004-07-01
公開日2004-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
1VQN
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The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
1VQ8
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The structure of CCDA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1W6M
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X-RAY CRYSTAL STRUCTURE OF C2S HUMAN GALECTIN-1 COMPLEXED WITH GALACTOSE
分子名称: BETA-MERCAPTOETHANOL, GALECTIN-1, SULFATE ION, ...
著者Lopez-Lucendo, M.I.F, Gabius, H.J, Romero, A.
登録日2004-08-19
公開日2004-10-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Growth-Regulatory Human Galectin-1: Crystallographic Characterisation of the Structural Changes Induced by Single-Site Mutations and Their Impact on the Thermodynamics of Ligand Binding.
J.Mol.Biol., 343, 2004
1VQK
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The structure of CCDA-PHE-CAP-BIO bound to the a site of the ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1T94
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Crystal structure of the catalytic core of human DNA polymerase kappa
分子名称: polymerase (DNA directed) kappa
著者Uljon, S.N, Johnson, R.E, Edwards, T.A, Prakash, S, Prakash, L, Aggarwal, A.K.
登録日2004-05-14
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the catalytic core of human DNA polymerase kappa.
STRUCTURE, 12, 2004
1TEZ
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COMPLEX BETWEEN DNA AND THE DNA PHOTOLYASE FROM ANACYSTIS NIDULANS
分子名称: 5'-D(*AP*TP*CP*GP*GP*CP*T*(TCP)P*CP*GP*C)-3', 5'-D(*TP*CP*GP*C)-3', 5'-D(P*CP*GP*AP*AP*GP*CP*CP*GP*A)-3', ...
著者Essen, L.-O, Carell, T, Mees, A, Klar, T.
登録日2004-05-26
公開日2004-12-14
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair
Science, 306, 2004
1TG8
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The structure of Dengue virus E glycoprotein
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1M1K
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Co-crystal structure of azithromycin bound to the 50S ribosomal subunit of Haloarcula marismortui
分子名称: 23S RRNA, 5S RRNA, AZITHROMYCIN, ...
著者Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
登録日2002-06-19
公開日2002-07-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1M6X
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Flpe-Holliday Junction Complex
分子名称: Flp recombinase, Symmetrized FRT site
著者Conway, A.B, Chen, Y, Rice, P.A.
登録日2002-07-17
公開日2003-02-04
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Plasticity of the Flp-Holliday Junction Complex
J.Mol.Biol., 326, 2003

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