PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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3O9F	Crystal Structure of wild-type HIV-1 Protease in complex with kd27 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-3-{(2-ethylbutyl)[(4-methoxyphenyl)sulfonyl]amino}-2-hydroxypropyl]carbamate, ACETATE ION, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2010-08-04 公開日 2011-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem.Biol., 20, 2013
4CIO	RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA 分子名称: 5'-R(*GP*GP*UP*GP*UP*GP*CP)-3', PROTEIN SUP-12, ISOFORM A 著者 Amrane, S, Mackereth, C.D. 登録日 2013-12-12 公開日 2014-09-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition Nat.Commun., 5, 2014
4CHA	STRUCTURE OF ALPHA-*CHYMOTRYPSIN REFINED AT 1.68 ANGSTROMS RESOLUTION 分子名称: ALPHA-CHYMOTRYPSIN A 著者 Tsukada, H, Blow, D.M. 登録日 1984-11-26 公開日 1985-04-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure of alpha-chymotrypsin refined at 1.68 A resolution. J.Mol.Biol., 184, 1985
3NPS	Crystal structure of membrane-type serine protease 1 (MT-SP1) in complex with the Fab Inhibitor S4 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, S4 FAB HEAVY CHAIN, ... 著者 Baharuddin, A. 登録日 2010-06-29 公開日 2011-07-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A reverse binding motif that contributes to specific protease inhibition by antibodies. J.Mol.Biol., 415, 2012
4DBR	Myosin VI D179Y (MD) pre-powerstroke state 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Pylypenko, O, Sweeney, H.L, Houdusse, A. 登録日 2012-01-16 公開日 2013-01-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating To be Published
3O2Y	Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid 分子名称: GLYCEROL, OLEIC ACID, PALMITIC ACID, ... 著者 Zhou, Y, Shaw, N, Li, Y, Zhao, Y, Zhang, R, Liu, Z.-J. 登録日 2010-07-23 公開日 2010-09-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid To be Published
6F1F	The methylene thioacetal BPTI (Bovine Pancreatic Trypsin Inhibitor) mutant structure 分子名称: GLYCEROL, Pancreatic trypsin inhibitor, SULFATE ION 著者 Lansky, S, Mousa, R, Metanis, N, Shoham, G. 登録日 2017-11-21 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.716 Å) 主引用文献 BPTI folding revisited: switching a disulfide into methylene thioacetal reveals a previously hidden path. Chem Sci, 9, 2018
6F1M	Lysozyme crystallized in presence of 100 mM sodium phosphate at pH 4.5: low-humidity form 分子名称: Lysozyme C 著者 Camara-Artigas, A. 登録日 2017-11-22 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Orthorhombic lysozyme crystallization at acidic pH values driven by phosphate binding. Acta Crystallogr D Struct Biol, 74, 2018
6F1O	Orthorhombic Lysozyme crystallized at 298 K and pH 4.5 分子名称: CHLORIDE ION, Lysozyme C, PHOSPHATE ION 著者 Camara-Artigas, A. 登録日 2017-11-22 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Orthorhombic lysozyme crystallization at acidic pH values driven by phosphate binding. Acta Crystallogr D Struct Biol, 74, 2018
7EHX	X-ray crystal strcture of F46C/L49C sperm whale myoglobin with an intramolecular disulfide bond 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Lin, Y.W. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal strcture of F46C/L49C sperm whale myoglobin with an intramolecular disulfide bond To Be Published
4DPI	BACE-1 in complex with HEA-macrocyclic inhibitor, MV078512 分子名称: (4S,8E,11R)-4-[(1R)-1-hydroxy-2-{[3-(propan-2-yl)benzyl]amino}ethyl]-16-methyl-11-phenyl-6-oxa-3,12-diazabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione, Beta-secretase 1 著者 Lindberg, J, Borkakoti, N, Derbyshire, D. 登録日 2012-02-13 公開日 2012-07-11 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes. Bioorg.Med.Chem., 20, 2012
7EJV	The co-crystal structure of DYRK2 with YK-2-69 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [6-[[4-[2-(dimethylamino)-1,3-benzothiazol-6-yl]-5-fluoranyl-pyrimidin-2-yl]amino]pyridin-3-yl]-(4-ethylpiperazin-1-yl)methanone 著者 Li, Z, Xiao, Y, Yuan, K, Kuang, W, Xiuquan, Y, Yang, P. 登録日 2021-04-02 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer. Nat Commun, 13, 2022
4DJ5	Proteinase K by Langmuir-Blodgett Hanging Drop Method at 1.8A resolution for Unique Water Distribution 分子名称: Proteinase K 著者 Pechkova, E, Sivozhelezov, V, Belmonte, L, Nicolini, C. 登録日 2012-02-01 公開日 2012-07-18 最終更新日 2012-10-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Unique water distribution of Langmuir-Blodgett versus classical crystals. J.Struct.Biol., 180, 2012
3NX0	Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C 分子名称: Cystatin-C, SULFATE ION 著者 Orlikowska, M, Jankowska, E, Kolodziejczyk, R, Jaskolski, M, Szymanska, A. 登録日 2010-07-12 公開日 2010-12-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C. J.Struct.Biol., 173, 2011
3O9G	Crystal Structure of wild-type HIV-1 Protease in complex with af53 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-3-[(2-ethylbutyl){[4-(hydroxymethyl)phenyl]sulfonyl}amino]-2-hydroxypropyl}carbamate, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2010-08-04 公開日 2011-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem.Biol., 20, 2013
6F60	The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand 分子名称: Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound 著者 Merlino, A, Ferraro, G. 登録日 2017-12-04 公開日 2018-04-25 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules. Inorg Chem, 57, 2018
3NXE	X-ray structure of ester chemical analogue 'covalent dimer' [Ile50,O-Ile50']HIV-1 protease complexed with MVT-101 inhibitor 分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, protease covalent dimer 著者 Torbeev, V.Y, Kent, S.B.H. 登録日 2010-07-13 公開日 2011-11-02 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011
4DUS	Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Sickmier, E.A. 登録日 2012-02-22 公開日 2012-10-10 最終更新日 2014-07-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012
4DLX	H-Ras Set 1 CaCl2/DTE, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.731 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
6F76	Antibody derived (Abd-8) small molecule binding to KRAS. 分子名称: 4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline, GTPase KRas, MAGNESIUM ION, ... 著者 Bery, N, Cruz-Migoni, A, Quevedo, C.E, Phillips, S.V.E, Carr, S, Rabbitts, T.H. 登録日 2017-12-07 公開日 2018-08-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife, 7, 2018
3NNH	Crystal Structure of the CUGBP1 RRM1 with GUUGUUUUGUUU RNA 分子名称: CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3') 著者 Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. 登録日 2010-06-23 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7501 Å) 主引用文献 Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
6FD8	Gamma-s crystallin dimer 分子名称: Beta-crystallin S 著者 Mabbitt, P.D, Thorn, D.C, Jackson, C.J, Carver, J.A. 登録日 2017-12-22 公開日 2018-12-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structure and Stability of the Disulfide-Linked gamma S-Crystallin Dimer Provide Insight into Oxidation Products Associated with Lens Cataract Formation. J. Mol. Biol., 431, 2019
4DD1	EVAL processed HEWL, cisplatin aqueous paratone 分子名称: 2-methylprop-1-ene, Lysozyme C 著者 Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. 登録日 2012-01-18 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
3NQ3	Bovine beta-lactoglobulin complex with capric acid 分子名称: Beta-lactoglobulin, CHLORIDE ION, DECANOIC ACID, ... 著者 Loch, J.I, Lewinski, K. 登録日 2010-06-29 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Two modes of fatty acid binding to bovine beta-lactoglobulin-crystallographic and spectroscopic studies J.Mol.Recognit., 24, 2011
4DDA	EVAL processed HEWL, NAG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C 著者 Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. 登録日 2012-01-18 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012

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