3NX0

Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C

Summary for 3NX0

Entry DOI	10.2210/pdb3nx0/pdb
Descriptor	Cystatin-C, SULFATE ION (3 entities in total)
Functional Keywords	cysteine protease inhibitor, 3d domain swapping, protein engineering, protein oligomerization, protein aggregation, amyloid, hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Secreted: P01034
Total number of polymer chains	2
Total formula weight	26952.35
Authors	Orlikowska, M.,Jankowska, E.,Kolodziejczyk, R.,Jaskolski, M.,Szymanska, A. (deposition date: 2010-07-12, release date: 2010-12-01, Last modification date: 2011-07-13)
Primary citation	Orlikowska, M.,Jankowska, E.,Kolodziejczyk, R.,Jaskolski, M.,Szymanska, A. Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C. J.Struct.Biol., 173:406-413, 2011 Cited by PubMed: 21074623 DOI: 10.1016/j.jsb.2010.11.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation