3NX0
Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cystatin-C | polymer | 120 | 13380.1 | 2 | UniProt (P01034) Pfam (PF00031) | Homo sapiens (human) | Cystatin-3, Neuroendocrine basic polypeptide, Gamma-trace, Post-gamma-globulin |
| 2 | C, D (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 120 (UniProt: P01034)
| PDB | External Database | Details |
|---|---|---|
| Asn 57 | Val 83 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26760.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 26952.3 |
