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4TVR
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BU of 4tvr by Molmil
Tandem Tudor and PHD domains of UHRF2
分子名称: E3 ubiquitin-protein ligase UHRF2, UNKNOWN ATOM OR ION, ZINC ION
著者Walker, J.R, Dong, A, Zhang, Q, Ong, M, Duan, S, Li, Y, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日2014-06-27
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of the Tandem Tudor and PHD domains of UHRF2
To be published
4U3Y
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BU of 4u3y by Molmil
Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)
分子名称: DIMETHYL SULFOXIDE, Mitogen-activated protein kinase kinase kinase kinase 4
著者Harris, S.F, Wu, P, Coons, M.
登録日2014-07-23
公開日2016-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Plasticity and Kinase Activation in a Cohort of MAP4K4 Structures
to be published
4V4Q
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BU of 4v4q by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D.
登録日2005-08-30
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
4V4P
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BU of 4v4p by Molmil
Crystal structure of 70S ribosome with thrS operator and tRNAs.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Jenner, L, Romby, P, Rees, B, Schulze-Briese, C, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D, Yusupova, G, Yusupov, M.
登録日2005-01-19
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding.
Science, 308, 2005
4V54
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BU of 4v54 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V52
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BU of 4v52 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V4J
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BU of 4v4j by Molmil
Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome.
分子名称: 16S RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Trakhanov, S, Asahara, H, Laurberg, M, Noller, H.F.
登録日2007-07-18
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.83 Å)
主引用文献Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4V57
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BU of 4v57 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
登録日2007-07-21
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
4V9H
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BU of 4v9h by Molmil
Crystal structure of the ribosome bound to elongation factor G in the guanosine triphosphatase state
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V.
登録日2013-03-25
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (2.857 Å)
主引用文献Elongation factor G bound to the ribosome in an intermediate state of translocation.
Science, 340, 2013
7LX6
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BU of 7lx6 by Molmil
T4 lysozyme mutant L99A
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(2-phenylethyl)sulfanyl]-1H-1,2,3-triazole, Lysozyme
著者Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K.
登録日2021-03-03
公開日2021-09-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Energy penalties enhance flexible receptor docking in a model cavity.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LT6
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BU of 7lt6 by Molmil
Structure of Partial Beta-Hairpin LIR from FNIP2 Bound to GABARAP
分子名称: Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein
著者Appleton, B.A.
登録日2021-02-18
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Sci Adv, 7, 2021
7MD7
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BU of 7md7 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with triphenylphosphonium analog of chloramphenicol CAM-C4-TPP and protein Y (YfiA) at 2.80A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Pavlova, J.A, Lukianov, D.A, Tereshchenkov, A.G, Makarov, G.I, Khairullina, Z.Z, Tashlitsky, V.N, Paleskava, A, Konevega, A.L, Bogdanov, A.A, Osterman, I.A, Sumbatyan, N.V, Polikanov, Y.S.
登録日2021-04-03
公開日2021-04-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome.
Antibiotics, 10, 2021
6ZQR
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BU of 6zqr by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6QEY
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BU of 6qey by Molmil
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
分子名称: ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION
著者Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A.
登録日2019-01-09
公開日2019-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Res., 47, 2019
6D4K
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BU of 6d4k by Molmil
Crystal structure of L,D-transpeptidase 3 from Mycobacterium tuberculosis at 1.32 A resolution
分子名称: CALCIUM ION, Probable L,D-transpeptidase 3
著者Libreros, G.A, Dias, M.V.B.
登録日2018-04-18
公開日2019-02-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural Basis for the Interaction and Processing of beta-Lactam Antibiotics by l,d-Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis.
ACS Infect Dis, 5, 2019
6Q6X
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BU of 6q6x by Molmil
Structure of Fucosylated D-antimicrobial peptide SB6 in complex with the Fucose-binding lectin PA-IIL at 1.525 Angstrom resolution
分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, AMINO GROUP, CALCIUM ION, ...
著者Baeriswyl, S, Stocker, A, Reymond, J.-L.
登録日2018-12-12
公開日2019-03-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.525 Å)
主引用文献X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
6Q77
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BU of 6q77 by Molmil
Structure of Fucosylated D-antimicrobial peptide SB12 in complex with the Fucose-binding lectin PA-IIL at 2.002 Angstrom resolution
分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin, ...
著者Baeriswyl, S, Stocker, A, Reymond, J.-L.
登録日2018-12-12
公開日2019-03-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
6QL8
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BU of 6ql8 by Molmil
Cathepsin-K in complex with MIV-711
分子名称: Cathepsin K, NITRATE ION, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-ethynyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-[5-fluoranyl-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
著者Derbyshire, D.J.
登録日2019-01-31
公開日2020-02-19
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K.
To Be Published
6DFL
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BU of 6dfl by Molmil
WaaP in complex with acyl carrier protein
分子名称: Acyl carrier protein, Lipopolysaccharide core heptose(I) kinase RfaP, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexadecanethioate
著者Chopra, R, Vash, B.
登録日2018-05-15
公開日2019-04-03
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase.
Sci Rep, 8, 2018
6D9D
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BU of 6d9d by Molmil
Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-GlcNAc (open, oxidized)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, SODIUM ION, ...
著者Wangkanont, K, Kiessling, L.L, Forest, K.T.
登録日2018-04-28
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate recognition by FAD in UDP-galactopyranose mutase
To be published
6DCH
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BU of 6dch by Molmil
Structure of isonitrile biosynthesis enzyme ScoE
分子名称: ACETATE ION, CHLORIDE ION, CHOLINE ION, ...
著者Born, D.A, Drennan, C.L.
登録日2018-05-07
公開日2018-06-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase.
Angew. Chem. Int. Ed. Engl., 57, 2018
6Q79
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BU of 6q79 by Molmil
Structure of Fucosylated D-antimicrobial peptide SB4 in complex with the Fucose-binding lectin PA-IIL at 2.009 Angstrom resolution
分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, AMINO GROUP, CALCIUM ION, ...
著者Baeriswyl, S, Stocker, A, Reymond, J.-L.
登録日2018-12-13
公開日2019-03-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
6QFH
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BU of 6qfh by Molmil
Crystal Structure of Human Kallikrein 6 (N217D/I218Y/K224R) in complex with GSK144.
分子名称: 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6
著者Thorpe, J.H.
登録日2019-01-10
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr.,Sect.F, 75, 2019
6DNV
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BU of 6dnv by Molmil
Crystal Structure of Neisseria meningitidis DsbD n-terminal domain in the reduced form
分子名称: SULFATE ION, Thiol:disulfide interchange protein DsbD
著者Smith, R.P, Heras, B, Paxman, J.J.
登録日2018-06-08
公開日2018-09-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
6QFE
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BU of 6qfe by Molmil
Crystal Structure of Human Kallikrein 5 in complex with GSK144
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, ...
著者Thorpe, J.H.
登録日2019-01-10
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr.,Sect.F, 75, 2019

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