PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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5IYD	Human core-PIC in the initial transcribing state (no IIS) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
8HAL	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 分子名称: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAG	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution) 分子名称: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8H3I	Crystal Structure of the apo-form Pathogenesis-related Protein HcPR10 from Halostachys caspica 分子名称: PR10 著者 Wang, Z, Ren, Y. 登録日 2022-10-08 公開日 2023-05-17 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Halostachys caspica pathogenesis-related protein 10 acts as a cytokinin reservoir to regulate plant growth and development. Front Plant Sci, 14, 2023
8HAH	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution) 分子名称: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAI	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution) 分子名称: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAM	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 分子名称: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAJ	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution) 分子名称: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAN	Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3 分子名称: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8HAK	Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 4 (4.5 angstrom resolution) 分子名称: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. 登録日 2022-10-26 公開日 2023-05-17 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
8H3J	Crystal Structure of Pathogenesis-related Protein HcPR10 from Halostachys caspica in complex with trans-Zeatin-riboside 分子名称: N-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]adenosine, PR10 著者 Wang, Z, Ren, Y. 登録日 2022-10-08 公開日 2023-05-17 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Halostachys caspica pathogenesis-related protein 10 acts as a cytokinin reservoir to regulate plant growth and development. Front Plant Sci, 14, 2023
3JYP	Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH 分子名称: (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Quinate/shikimate dehydrogenase 著者 Hoeppner, A, Schomburg, D, Niefind, K. 登録日 2009-09-22 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination. Biol.Chem., 394, 2013
6RA9	Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus 分子名称: Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Carriles, A.A, Hermoso, J, Gago, F. 登録日 2019-04-05 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Cues for Understanding eEF1A2 Moonlighting. Chembiochem, 22, 2021
5CWR	Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-07-28 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
3JU6	Crystal Structure of Dimeric Arginine Kinase in Complex with AMPPNP and Arginine 分子名称: ARGININE, Arginine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Wu, X, Ye, S, Guo, S, Yan, W, Bartlam, M, Rao, Z. 登録日 2009-09-14 公開日 2009-09-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J., 24, 2010
5G5S	Structure of the Argonaute protein from Methanocaldcoccus janaschii 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGONAUTE, MAGNESIUM ION 著者 Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S. 登録日 2016-06-03 公開日 2017-02-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein. Nat Microbiol, 2, 2017
2XE8	The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and AMP-PNP 分子名称: 3-PHOSPHOGLYCERIC ACID, PHOSPHOGLYCERATE KINASE 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. 登録日 2010-05-11 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
2BGU	CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE 分子名称: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE 著者 Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. 登録日 1994-06-09 公開日 1995-12-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. EMBO J., 13, 1994
3JYQ	Quinate dehydrogenase from Corynebacterium glutamicum in complex with shikimate and NADH 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Quinate/shikimate dehydrogenase 著者 Hoeppner, A, Schomburg, D, Niefind, K. 登録日 2009-09-22 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination. Biol.Chem., 394, 2013
5Y70	NMR structure of KMP11 in DPC micelle 分子名称: Kinetoplastid membrane protein 11 著者 Lu, Y, Lim, L.Z, Song, J. 登録日 2017-08-16 公開日 2018-02-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Kinetoplastid membrane protein-11 adopts a four-helix bundle fold in DPC micelle. FEBS Lett., 591, 2017
4JWE	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(1-21) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
2XE7	The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and ADP 分子名称: 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, PHOSPHOGLYCERATE KINASE 1 著者 Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. 登録日 2010-05-11 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
1HJB	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER 分子名称: CCAAT/ENHANCER BINDING PROTEIN BETA, DNA (5'-(*CP*CP*GP*CP*AP*AP*CP*CP*AP*CP* AP*GP*AP*GP*TP*TP*TP*GP*GP*AP*AP*AP*TP*CP*TP*T)-3'), DNA (5'-(*GP*AP*AP*GP*AP*TP*TP*TP*CP*CP* AP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP*TP*TP*GP*CP*G)-3'), ... 著者 Tahirov, T.H, Ogata, K. 登録日 2001-01-11 公開日 2001-03-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta Cell(Cambridge,Mass.), 104, 2001
3K47	Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase 分子名称: 5-[(1E)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Pace, J, Queener, S.F, Gangjee, A. 登録日 2009-10-05 公開日 2009-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg.Med.Chem., 17, 2009
5AGI	Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP 分子名称: GLYCEROL, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE 著者 Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A. 登録日 2015-02-02 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism. Acs Chem.Biol., 10, 2015

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