1S1G
| Crystal Structure of Kv4.3 T1 Domain | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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7ZNY
| Cryo-EM structure of the canine distemper virus tetrameric attachment glycoprotein | 分子名称: | Hemagglutinin glycoprotein | 著者 | Kalbermatter, D, Jeckelmann, J.-M, Wyss, M, Plattet, P, Fotiadis, D. | 登録日 | 2022-04-23 | 公開日 | 2023-02-08 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. Proc.Natl.Acad.Sci.USA, 120, 2023
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5JKV
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5IVW
| Human core TFIIH bound to DNA within the PIC | 分子名称: | General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-21 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY7
| Human holo-PIC in the open state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5FMF
| the P-lobe of RNA polymerase II pre-initiation complex | 分子名称: | DNA REPAIR HELICASE RAD25, SSL2, DNA REPAIR HELICASE RAD3, ... | 著者 | Murakami, K, Tsai, K, Kalisman, N, Bushnell, D.A, Asturias, F.J, Kornberg, R.D. | 登録日 | 2015-11-03 | 公開日 | 2015-11-25 | 最終更新日 | 2017-07-12 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of an RNA Polymerase II Pre-Initiation Complex Proc.Natl.Acad.Sci.USA, 112, 2015
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2YIS
| triazolopyridine inhibitors of p38 kinase. | 分子名称: | 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, MITOGEN-ACTIVATED PROTEIN KINASE 14 | 著者 | Millan, D.S, Anderson, M, Bazin, R, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthwaite, R.A, Mahnke, A, Mathais, J.P, Philip, J, Phillips, C, Smith, R.T, Stefaniack, M.H, Yeadon, M. | 登録日 | 2011-05-16 | 公開日 | 2011-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease. J.Med.Chem., 54, 2011
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5T2O
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5T2H
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5T2N
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6VLT
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5IUT
| STRUCTURE OF P450 2B4 F202W MUTANT | 分子名称: | 3,6,9,12,15,18-hexaoxahexacosan-1-ol, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Jang, H.-H, Halpert, J.R, Shah, M.B. | 登録日 | 2016-03-18 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophys.Chem., 216, 2016
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4G1N
| PKM2 in complex with an activator | 分子名称: | MAGNESIUM ION, N-(4-{[4-(pyrazin-2-yl)piperazin-1-yl]carbonyl}phenyl)quinoline-8-sulfonamide, OXALATE ION, ... | 著者 | Kung, C, Hixon, J, Dang, L, DeLaBarre, B, Qian, K.C. | 登録日 | 2012-07-10 | 公開日 | 2012-10-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy. Chem.Biol., 19, 2012
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5LVO
| Human PDK1 Kinase Domain in Complex with Allosteric Compound PSE10 Bound to the PIF-Pocket | 分子名称: | 2-oxidanylidenepropyl ~{N}-(2-chloranyl-6-fluoranyl-phenyl)carbonyl-~{N}'-(4-chlorophenyl)carbamimidothioate, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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5MS5
| Low-salt structure of RavZ LIR2-fused human LC3B | 分子名称: | GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | 著者 | Pantoom, S, Vetter, I.R, Wu, Y.W. | 登録日 | 2016-12-31 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. Elife, 6, 2017
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5MS8
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1KPI
| Crystal Structure of mycolic acid cyclopropane synthase CmaA2 complexed with SAH and DDDMAB | 分子名称: | CARBONATE ION, CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2, DIDECYL-DIMETHYL-AMMONIUM, ... | 著者 | Huang, C.-C, Smith, C.V, Jacobs Jr, W.R, Glickman, M.S, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2001-12-30 | 公開日 | 2002-01-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis J.Biol.Chem., 277, 2002
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5MTC
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
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3N5B
| The complex of PII and PipX from Anabaena | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Asr0485 protein, Nitrogen regulatory protein P-II, ... | 著者 | Jiang, Y.-L, Zhao, M.-X, Xu, B.-Y, Chen, Y.-X, Zhang, C.-C, Zhou, C.-Z. | 登録日 | 2010-05-24 | 公開日 | 2010-09-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the cyanobacterial signal transduction protein PII in complex with PipX. J.Mol.Biol., 402, 2010
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1U7B
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5HQT
| Crystal structure of an aspartate/glutamate racemase from Escherichia coli O157 | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, aspartate/glutamate racemase | 著者 | Liu, X, Gao, F, Ma, Y, Liu, S, Cui, Y, Yuan, Z, Kang, X. | 登録日 | 2016-01-22 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | 主引用文献 | Crystal structure and molecular mechanism of an aspartate/glutamate racemase from Escherichia coli O157 Febs Lett., 590, 2016
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6W13
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5MPW
| Crystal structure of Arabidopsis thaliana RNA editing factor MORF1 | 分子名称: | BROMIDE ION, Multiple organellar RNA editing factor 1, mitochondrial, ... | 著者 | Haag, S, Schindler, M, Berndt, L, Brennicke, A, Takenaka, M, Weber, G. | 登録日 | 2016-12-19 | 公開日 | 2017-02-22 | 最終更新日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9. Nucleic Acids Res., 45, 2017
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1TVM
| NMR structure of enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system | 分子名称: | PTS system, galactitol-specific IIB component | 著者 | Volpon, L, Young, C.R, Lim, N.S, Iannuzzi, P, Cygler, M, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2004-06-29 | 公開日 | 2005-09-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA. Protein Sci., 15, 2006
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3S4Q
| P38 alpha kinase complexed with a pyrazolo-triazine based inhibitor | 分子名称: | 3-[(6-benzoyl-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]-N-cyclopropyl-4-methylbenzamide, Mitogen-activated protein kinase 14 | 著者 | Sack, J.S. | 登録日 | 2011-05-20 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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