PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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3M0Q	Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 5. 分子名称: SULFATE ION, Spectrin alpha chain, brain 著者 Camara-Artigas, A, Gavira, J.A. 登録日 2010-03-03 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures Acta Crystallogr.,Sect.D, 2011
4CK8	STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 4-(4-(3,4- dichlorophenyl)piperazin-1-yl)phenylcarbamate (LFD) 分子名称: (1R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl {4-[4-(3,4-dichlorophenyl)piperazin-1-yl]phenyl}carbamate, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Friggeri, L, Wawrzak, Z, Tortorella, S, Lepesheva, G.I. 登録日 2013-12-30 公開日 2014-07-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma Cruzi Sterol 14Alpha-Demethylase: Two Regions of the Enzyme Molecule Potentiate its Inhibition. J.Med.Chem., 57, 2014
3MVR	Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2010-05-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography. J.Biol.Chem., 285, 2010
3MWS	Crystal Structure of Group N HIV-1 Protease 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease 著者 Sayer, J.M, Agniswamy, J, Weber, I.T, Louis, J.M. 登録日 2010-05-06 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance. Protein Sci., 19, 2010
6DV0	HIV-1 wild type protease with GRL-02815A, a thiochroman heterocycle with (S)-Boc-amine functionality as the P2 ligand 分子名称: CHLORIDE ION, GLYCEROL, Protease, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2018-06-22 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands. Eur J Med Chem, 160, 2018
3MWZ	Crystal structure of the selenomethionine derivative of the L 22,47,100 M mutant of sialostatin L2 分子名称: SULFATE ION, sialostatin L2 著者 Andersen, J.F. 登録日 2010-05-06 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Mol.Microbiol., 77, 2010
3MX8	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: CHLORIDE ION, Ribonuclease pancreatic, LINKER, ... 著者 Leich, F, Neumann, P, Lilie, H, Ulbrich-Hofmann, R, Arnold, U. 登録日 2010-05-07 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011
3MXH	Native structure of a c-di-GMP riboswitch from V. cholerae 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... 著者 Strobel, S.A, Smith, K.D. 登録日 2010-05-07 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
3MYN	Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin 分子名称: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bowden, E.F, de Serrano, V.S, D'Antonio, E.L, Franzen, S. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin. Biochemistry, 50, 2011
6DG1	NMR structure of the second qRRM2 domain of human hnRNP H 分子名称: qRRM2 domain of Heterogeneous nuclear ribonucleoprotein H2 著者 Srinivasa, R.P. 登録日 2018-05-16 公開日 2018-09-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H. J. Am. Chem. Soc., 2018
7D7V	Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein 分子名称: 17delU1A (58-MER), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Chen, H, Ren, A.M. 登録日 2020-10-06 公開日 2020-11-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding. Nucleic Acids Res., 48, 2020
4CFY	SAVINASE CRYSTAL STRUCTURES FOR COMBINED SINGLE CRYSTAL DIFFRACTION AND POWDER DIFFRACTION ANALYSIS 分子名称: CALCIUM ION, SODIUM ION, SUBTILISIN SAVINASE 著者 Frankaer, C.G, Moroz, O.V, Turkenburg, J.P, Aspmo, S.I, Thymark, M, Friis, E.P, Stahla, K, Nielsen, J.E, Wilson, K.S, Harris, P. 登録日 2013-11-19 公開日 2014-04-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Analysis of an Industrial Production Suspension of Bacillus Lentus Subtilisin Crystals by Powder Diffraction: A Powerful Quality-Control Tool. Acta Crystallogr.,Sect.D, 70, 2014
4CK4	Ovine beta-Lactoglobulin at Atomic Resolution 分子名称: ACETATE ION, AMMONIUM ION, BETA_LACTOGLOBULIN-1/B, ... 著者 Kontopidis, G, Nordle, A, Sawyer, L. 登録日 2013-12-27 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Ovine Beta-Lactoglobulin at Atomic Resolution Acta Crystallogr.,Sect.F, 70, 2014
6DZF	Orthorhombic trypsin cryocooled to 100 K with 20% xylose as cryoprotectant 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Juers, D.H. 登録日 2018-07-03 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
7D0W	Crystal structure of Hen Egg White Lysozyme 分子名称: CHLORIDE ION, Lysozyme C 著者 Iqbal, S, Krishnasamy, G. 登録日 2020-09-12 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Hen Egg White Lysozyme To Be Published
6DZH	HRAS G13D bound to GDP (H13GDP) 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GLYCEROL, ... 著者 Johnson, C.W, Mattos, C. 登録日 2018-07-04 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
6E02	WT swMb-MeNO 分子名称: Myoglobin, NITROSOMETHANE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Herrera, V.E. 登録日 2018-07-05 公開日 2019-07-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Insights into Nitrosoalkane Binding to Myoglobin Provided by Crystallography of Wild-Type and Distal Pocket Mutant Derivatives. Biochemistry, 62, 2023
3MWQ	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: GLYCEROL, Ribonuclease pancreatic, LINKER, ... 著者 Neumann, P, Leich, F. 登録日 2010-05-06 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011
3N3I	Crystal Structure of G48V/C95F tethered HIV-1 Protease/Saquinavir complex 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease 著者 Prashar, V, Bihani, S.C, Das, A, Rao, D.R, Hosur, M.V. 登録日 2010-05-20 公開日 2010-06-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Insights into the mechanism of drug resistance: X-ray structure analysis of G48V/C95F tethered HIV-1 protease dimer/saquinavir complex Biochem.Biophys.Res.Commun., 396, 2010
4CK9	STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (S)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethyl 4- isopropylphenylcarbamate (LFT) 分子名称: (1S)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethyl [4-(propan-2-yl)phenyl]carbamate, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Friggeri, L, Wawrzak, Z, Tortorella, S, Lepesheva, G.I. 登録日 2013-12-31 公開日 2014-07-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma Cruzi Sterol 14Alpha-Demethylase: Two Regions of the Enzyme Molecule Potentiate its Inhibition. J.Med.Chem., 57, 2014
6E03	sperm whale myoglobin nitrosoethane adduct 分子名称: CHLORIDE ION, Myoglobin, NITROSOETHANE, ... 著者 Herrera, V.E. 登録日 2018-07-05 公開日 2019-07-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Insights into Nitrosoalkane Binding to Myoglobin Provided by Crystallography of Wild-Type and Distal Pocket Mutant Derivatives. Biochemistry, 62, 2023
3MU5	Comparison of the character and the speed of X-ray-induced structural changes of porcine pancreatic elastase at two temperatures, 100 and 15K. The data set was collected from region B of the crystal. Third step of radiation damage 分子名称: Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION 著者 Petrova, T, Ginell, S, Mitschler, A, Cousido-Siah, A, Hazemann, I, Podjarny, A, Joachimiak, A. 登録日 2010-05-01 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.404 Å) 主引用文献 X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
3MUT	Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), G20A/C92U mutant c-di-GMP riboswitch, MAGNESIUM ION, ... 著者 Strobel, S.A, Smith, K.D. 登録日 2010-05-03 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
7DGN	The Co-bound dimeric structure of K79H/G80A/H81A myoglobin 分子名称: COBALT (II) ION, Myoglobin, OXYGEN ATOM, ... 著者 Nagao, S, Idomoto, A, Shibata, N, Higuchi, Y, Hirota, S. 登録日 2020-11-12 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Rational design of metal-binding sites in domain-swapped myoglobin dimers. J.Inorg.Biochem., 217, 2021
4CKU	Three dimensional structure of plasmepsin II in complex with hydroxyethylamine-based inhibitor 分子名称: 5-[1,1-bis(oxidanylidene)-1,2-thiazinan-2-yl]-N3-[(2S,3R)-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-butan-2-yl]-N1,N1-dipropyl-benzene-1,3-dicarboxamide, PLASMEPSIN-2 著者 Tars, K, Leitans, J, Jaudzems, K. 登録日 2014-01-08 公開日 2014-06-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit. Acs Med.Chem.Lett., 5, 2014

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