6PWD
 
 | | Ewingella americana HopBF1 kinase | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Type III effector HopBF1 | | 著者 | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | | 登録日 | 2019-07-22 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity.
Cell, 179, 2019
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6PWG
 | | Ewingella americana HopBF1 kinase bound to AMP-PNP | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type III effector HopBF1 | | 著者 | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | | 登録日 | 2019-07-23 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity.
Cell, 179, 2019
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6PU8
 | | Room temperature X-ray structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral intermediate of keto-darunavir | | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3,3-dihydroxy-1-phenylbutan-2-yl]carbamate, HIV-1 protease | | 著者 | Kovalevsky, A, Das, A. | | 登録日 | 2019-07-17 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design.
Acs Omega, 5, 2020
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6Q1G
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6Q1E
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6Q0H
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6Q18
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6PTP
 | | Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral intermediate mimic KVS-1 | | 分子名称: | HIV-1 Protease, N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl)amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide | | 著者 | Kovalevsky, A, Das, A. | | 登録日 | 2019-07-16 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | NEUTRON DIFFRACTION (1.85 Å), X-RAY DIFFRACTION | | 主引用文献 | Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design.
Acs Omega, 5, 2020
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7K4D
 | | Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 3OG | | 分子名称: | 5-[(4-{trans-4-hydroxy-4-[3-(trifluoromethyl)phenyl]cyclohexyl}piperazin-1-yl)methyl]pyridin-2(1H)-one, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. | | 登録日 | 2020-09-15 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
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7K4B
 | | Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(pyridin-3-yl)piperazine, CALCIUM ION, ... | | 著者 | Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. | | 登録日 | 2020-09-15 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
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6Q19
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6Q1A
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7LO1
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6Q0I
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6Q1K
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7LHQ
 | | Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0 | | 分子名称: | Non-structural protein 7 | | 著者 | Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W. | | 登録日 | 2021-01-26 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7
Biorxiv, 2021
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6Q0L
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7K4E
 | | Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 30 | | 分子名称: | 5-({4-[(1R,4S)-3'-methyl[1,2,3,4-tetrahydro[1,1'-biphenyl]]-4-yl]piperazin-1-yl}methyl)pyridin-2(1H)-one, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. | | 登録日 | 2020-09-15 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.34 Å) | | 主引用文献 | Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
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6Q0E
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6Q0O
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6QJP
 | | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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7LRD
 | | Cryo-EM of the SLFN12-PDE3A complex: Consensus subset model | | 分子名称: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Fuller, J.R, Garvie, C.W, Lemke, C.T. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
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7LRE
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7LRC
 | | Cryo-EM of the SLFN12-PDE3A complex: PDE3A body refinement | | 分子名称: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Fuller, J.R, Garvie, C.W, Lemke, C.T. | | 登録日 | 2021-02-16 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun, 12, 2021
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6O5D
 | | PYOCHELIN | | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, SULFATE ION | | 著者 | Rupert, P.B, Strong, R.K, Clifton, M.C, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2019-03-01 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands.
J Struct Biol X, 2, 2019
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