PDB: 221716 件ウェブページステータス検索Chemie searchBIRD

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5O3D	Human Brd2(BD2) mutant in complex with 9-ET 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
6GHY	Structure of Lytic Transglycosylase MltE inactive mutant E64Q from E.coli 分子名称: DI(HYDROXYETHYL)ETHER, Endo-type membrane-bound lytic murein transglycosylase A 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2018-05-09 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli. Biochemistry, 57, 2018
1BGA	BETA-GLUCOSIDASE A FROM BACILLUS POLYMYXA 分子名称: BETA-GLUCOSIDASE A 著者 Sanz-Aparicio, J, Hermoso, J.A, Martinez-Ripoll, M, Polaina, J. 登録日 1997-04-04 公開日 1998-04-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of beta-glucosidase A from Bacillus polymyxa: insights into the catalytic activity in family 1 glycosyl hydrolases. J.Mol.Biol., 275, 1998
5X5I	The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli 分子名称: HTH-type transcriptional regulator RcdA 著者 Sugino, H, Usui, M, Shimada, T, Nakano, M, Ogasawara, H, Ishihama, A, Hirata, A. 登録日 2017-02-16 公開日 2017-12-27 実験手法 X-RAY DIFFRACTION (2.554 Å) 主引用文献 A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation. FEBS Lett., 591, 2017
8RAT	EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K 分子名称: RIBONUCLEASE A 著者 Tiltonjunior, R.F, Dewan, J.C, Petsko, G.A. 登録日 1991-08-13 公開日 1993-07-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Biochemistry, 31, 1992
6FL3	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with myo-IP5 and ADP 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Inositol-pentakisphosphate 2-kinase, ... 著者 Whitfield, H.L, Brearley, C.A, Hemmings, A.M. 登録日 2018-01-25 公開日 2018-09-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase. J. Med. Chem., 61, 2018
5VB8	Crystal structure of the NavAb voltage-gated sodium channel in an open state 分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, SODIUM ION, ... 著者 Lenaeus, M.J, Catterall, W.A. 登録日 2017-03-28 公開日 2017-04-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structures of closed and open states of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UZU	Immune evasion by a Staphylococcal Peroxidase Inhibitor that blocks myeloperoxidase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 de Jong, N, Geisbrecht, B.V, van Strijp, J, Haas, P, Nijland, R, Ramyar, K, Fevre, C, Guerra, F, Voyich-Kane, J, van Kessel, C, Garcia, B. 登録日 2017-02-27 公開日 2017-07-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Immune evasion by a staphylococcal inhibitor of myeloperoxidase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1CLX	CATALYTIC CORE OF XYLANASE A 分子名称: CALCIUM ION, XYLANASE A 著者 Harris, G.W, Jenkins, J.A, Connerton, I, Pickersgill, R.W. 登録日 1995-08-31 公開日 1996-06-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Refined crystal structure of the catalytic domain of xylanase A from Pseudomonas fluorescens at 1.8 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
5JMC	Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C 分子名称: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C 著者 Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. 登録日 2016-04-28 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat.Struct.Mol.Biol., 23, 2016
6MW0	Mle-Phe-Mle-D-Phe. Linear tetrapeptide related to pseudoxylallemycin A. 分子名称: METHANOL, Mle-Phe-Mle-D-Phe Linear tetrapeptide related to pseudoxylallemycin A 著者 Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J. 登録日 2018-10-29 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (0.78 Å) 主引用文献 Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Org.Biomol.Chem., 17, 2019
6MW1	cyclo-Mle-Phe-Mle-Phe. Pseudoxylallemycin A. 分子名称: Pseudoxylallemycin A 著者 Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J. 登録日 2018-10-29 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (0.77 Å) 主引用文献 Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Org.Biomol.Chem., 17, 2019
1BH4	CIRCULIN A FROM CHASSALIA PARVIFLORA, NMR, 12 STRUCTURES 分子名称: CIRCULIN A 著者 Daly, N.L, Koltay, A, Craik, D.J. 登録日 1998-06-12 公開日 1999-06-15 最終更新日 2020-08-12 実験手法 SOLUTION NMR 主引用文献 Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity. J.Mol.Biol., 285, 1999
5W6G	Human antibody 6649 in complex with influenza hemagglutinin H1 Solomon Islands 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6649 antibody heavy chain, ... 著者 Raymond, D.D, Harrison, S.C. 登録日 2017-06-16 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6IBP	Structure of a psychrophilic CCA-adding enzyme at room temperature in ChipX microfluidic device 分子名称: CCA-adding enzyme 著者 de Wijn, R, Hennig, O, Rollet, K, Bluhm, A, Betat, H, Moerl, M, Lorber, B, Sauter, C. 登録日 2018-11-30 公開日 2019-05-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.536 Å) 主引用文献 A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography. Iucrj, 6, 2019
5N21	Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand 分子名称: 2-[(2~{S})-1-[3-cyano-7-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidin-2-yl]ethanoic acid, B-cell lymphoma 6 protein, CHLORIDE ION 著者 Robb, G, Ferguson, A, Hargreaves, D. 登録日 2017-02-06 公開日 2017-05-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
7LM9	Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient 分子名称: 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ... 著者 Liu, H, Yuan, M, Zhu, X, Wilson, I.A. 登録日 2021-02-05 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe, 29, 2021
6FJK	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with myo-IP6 and ADP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Whitfield, H.L, Brearley, C.A, Hemmings, A.M. 登録日 2018-01-22 公開日 2018-09-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.025 Å) 主引用文献 A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase. J. Med. Chem., 61, 2018
1CPX	BETA FORM OF CARBOXYPEPTIDASE A (RESIDUES 3-307) FROM BOVINE PANCREAS IN AN ORTHORHOMBIC CRYSTAL FORM WITH TWO ZINC IONS IN THE ACTIVE SITE. 分子名称: HYDROXIDE ION, PROTEIN (CARBOXYPEPTIDASE A), ZINC ION 著者 Bukrinsky, J.T, Bjerrum, M.J, Kadziola, A. 登録日 1998-07-27 公開日 1998-08-05 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Native carboxypeptidase A in a new crystal environment reveals a different conformation of the important tyrosine 248. Biochemistry, 37, 1998
6MW2	cyclo-Mle-Phe-Mle-D-Phe. D-Phe analogue of pseudoxylallemycin A. 分子名称: pseudoxylallemycin A 著者 Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J. 登録日 2018-10-29 公開日 2019-09-11 最終更新日 2019-10-02 実験手法 X-RAY DIFFRACTION (0.77 Å) 主引用文献 Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Org.Biomol.Chem., 17, 2019
6MHJ	Structure of BoNT mutant 分子名称: Botulinum neurotoxin type A, PHOSPHATE ION 著者 Lam, K, Jin, R. 登録日 2018-09-18 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.019 Å) 主引用文献 A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun, 9, 2018
6FYT	Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Laursen, N.S, Wilson, I.A. 登録日 2018-03-12 公開日 2018-11-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
6FQV	2.60A BINARY COMPLEX OF S.AUREUS GYRASE with UNCLEAVED DNA 分子名称: DNA (5'-D(*GP*AP*GP*CP*GP*TP*AP*CP*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, DNA gyrase subunit B,DNA gyrase subunit B, ... 著者 Bax, B.D, Germe, T, Basque, E, Maxwell, A. 登録日 2018-02-14 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance. Nucleic Acids Res., 46, 2018
5MQH	Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis in a crystal form without domain swapping 分子名称: Serine phosphatase 著者 Levdikov, V.M, Wilkinson, A.J, Blagova, E.V. 登録日 2016-12-20 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases. Elife, 6, 2017
5M7K	Blastochloris viridis photosynthetic reaction center - RC_vir_xfel 分子名称: (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL A, ... 著者 Sharma, A.S, Johansson, L, Dunevall, E, Wahlgren, W.Y, Neutze, R, Katona, G. 登録日 2016-10-28 公開日 2017-02-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Asymmetry in serial femtosecond crystallography data. Acta Crystallogr A Found Adv, 73, 2017

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