PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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5IT7	Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2 分子名称: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. 登録日 2016-03-16 公開日 2016-05-18 最終更新日 2018-11-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
2X1W	Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, ... 著者 Leppanen, V.M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K. 登録日 2010-01-08 公開日 2010-03-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2. Proc.Natl.Acad.Sci.USA, 107, 2010
2WWB	CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME 分子名称: 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... 著者 Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. 登録日 2009-10-22 公開日 2009-12-08 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.48 Å) 主引用文献 Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
2WW9	Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome 分子名称: 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... 著者 Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. 登録日 2009-10-22 公開日 2009-12-08 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.6 Å) 主引用文献 Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
8CGN	Non-rotated 80S S. cerevisiae ribosome with ligands 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-06 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.28 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CKU	Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-16 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CIV	Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-10 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CMJ	Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-20 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CA5	Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3). 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. 登録日 2023-01-24 公開日 2023-12-20 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
8C2S	Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. 登録日 2022-12-22 公開日 2023-12-20 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
8CA3	Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. 登録日 2023-01-24 公開日 2023-12-20 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
8CD1	70S-PHIKZ014 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Gerovac, M, Vogel, J. 登録日 2023-01-29 公開日 2024-01-24 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Phage proteins target and co-opt host ribosomes immediately upon infection. Nat Microbiol, 9, 2024
8C3A	Crystal structure of ailanthone bound to the Candida albicans 80S ribosome 分子名称: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... 著者 Kolosova, O, Zgadzay, Y, Yusupov, M. 登録日 2022-12-23 公開日 2024-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 New crystal system to promote screening for new eukaryotic inhibitors To Be Published
6CFW	cryoEM structure of a respiratory membrane-bound hydrogenase 分子名称: IRON/SULFUR CLUSTER, MBH subunit, Mbh13 NADH dehydrogenase subunit, ... 著者 Li, H.L, Yu, H.J. 登録日 2018-02-17 公開日 2018-05-23 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of an Ancient Respiratory System. Cell, 173, 2018
8CVJ	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMSEAC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8CVK	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8CVL	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-05-18 公開日 2022-10-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
8CVM	Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map 分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-18 公開日 2023-03-15 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
6DNC	E.coli RF1 bound to E.coli 70S ribosome in response to UAU sense A-site codon 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Demo, G, Korostelev, A.A. 登録日 2018-06-06 公開日 2018-07-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Mechanism of premature translation termination on a sense codon. J. Biol. Chem., 293, 2018
6DZP	Cryo-EM Structure of Mycobacterium smegmatis C(minus) 50S ribosomal subunit 分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Sharma, M.R, Li, Y, Korripella, R, Yang, Y, Kaushal, P.S, Lin, Q, Wade, J.T, Gray, A.G, Derbyshire, K.M, Agrawal, R.K, Ojha, A. 登録日 2018-07-05 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Zinc depletion induces ribosome hibernation in mycobacteria. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DZI	Cryo-EM Structure of Mycobacterium smegmatis 70S C(minus) ribosome 70S-MPY complex 分子名称: 16S rRNA, 23 S rRNA (3119-MER), 30S ribosomal protein S10, ... 著者 Sharma, M.R, Li, Y, Korripella, R, Yang, Y, Kaushal, P.S, Lin, Q, Wade, J.T, Gray, A.G, Derbyshire, K.M, Agrawal, R.K, Ojha, A. 登録日 2018-07-05 公開日 2018-09-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Zinc depletion induces ribosome hibernation in mycobacteria. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Kinashi, H, Rozenberg, H, Yonath, A. 登録日 2010-11-07 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Proc.Natl.Acad.Sci.USA, 108, 2011
6CAE	Crystal structure of the Thermus thermophilus 70S ribosome in complex with NOSO-95179 antibiotic and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Pantel, L, Florin, T, Dobosz-Bartoszek, M, Racine, E, Sarciaux, M, Serri, M, Houard, J, Campagne, J.M, Marcia de Figueiredo, R, Midrier, C, Gaudriault, S, Givaudan, A, Lanois, A, Forst, S, Aumelas, A, Cotteaux-Lautard, C, Bolla, J.M, Vingsbo Lundberg, C, Huseby, D, Hughes, D, Villain-Guillot, P, Mankin, A.S, Polikanov, Y.S, Gualtieri, M. 登録日 2018-01-30 公開日 2018-04-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site. Mol. Cell, 70, 2018
6BY1	E. coli pH03H9 complex 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Amiri, H, Noller, H.F. 登録日 2017-12-19 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 Structural evidence for product stabilization by the ribosomal mRNA helicase. Rna, 25, 2019
3PIO	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Arakawa, K, Kinashi, H, Rozenberg, H, Yonath, A. 登録日 2010-11-07 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2473 Å) 主引用文献 Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Proc.Natl.Acad.Sci.USA, 108, 2011

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