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2BIM
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human p53 core domain mutant M133L-V203A-N239Y-N268D-R273H
分子名称: CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
3D71
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Crystal structure of E253Q BMRR bound to 22 base pair promoter site
分子名称: BMR promoter DNA, CITRATE ANION, IMIDAZOLE, ...
著者Newberry, K.J, Huffman, J.L, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
5ZKO
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Crystal structure of the CRTC2-CREB-CRE complex
分子名称: CREB-regulated transcription coactivator 2, Cyclic AMP-responsive element-binding protein 1, DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3')
著者Xiang, S, Zhai, L, Valecia-Swain, J.
登録日2018-03-24
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural Insights into the CRTC2-CREB Complex Assembly on CRE.
J. Mol. Biol., 430, 2018
3D70
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Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide
分子名称: BMR promoter DNA, GLYCEROL, IMIDAZOLE, ...
著者Newberry, K.J, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
8HSR
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BU of 8hsr by Molmil
Thermus thermophilus Rho-engaged RNAP elongation complex (composite structure)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (31-MER), ...
著者Murayama, Y, Ehara, H, Sekine, S.
登録日2022-12-20
公開日2023-05-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Sci Adv, 9, 2023
1F5T
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DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
分子名称: 43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION
著者Chen, S, White, A, Love, J, Murphy, J.R, Ringe, D.
登録日2000-06-15
公開日2000-09-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Biochemistry, 39, 2000
8DQ1
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Quorum-sensing receptor RhlR bound to PqsE
分子名称: 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, DNA (5'-D(*AP*CP*CP*TP*GP*CP*CP*AP*GP*AP*CP*TP*GP*CP*AP*CP*AP*G)-3'), ...
著者Paczkowski, J.E, Fromme, J.C, Feathers, J.R.
登録日2022-07-18
公開日2022-12-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.
Structure, 30, 2022
5EJL
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MrkH, A novel c-di-GMP dependence transcription regulatory factor.
分子名称: 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Klebsiella pneumoniae genome assembly NOVST, ...
著者Wang, F, Zhu, D, Gu, L.
登録日2015-11-02
公開日2016-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The PilZ domain of MrkH represents a novel DNA binding motif
Protein Cell, 7, 2016
2C7A
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BU of 2c7a by Molmil
STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*AP*AP *CP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*TP *TP*TP*GP*TP*TP*CP*TP*G)-3', PROGESTERONE RECEPTOR, ...
著者Roemer, S.C, Donham, D.C, Sherman, L, Pon, V.H, Edwards, D.P, Churchill, M.E.A.
登録日2005-11-19
公開日2006-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Progesterone Receptor-Deoxyribonucleic Acid Complex: Novel Interactions Required for Binding to Half-Site Response Elements.
Mol.Endocrinol., 20, 2006
7Q3U
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Cryo-EM structure of TDP43 core peptide amyloid fiber
分子名称: TAR DNA-binding protein 43
著者Nazarov, S.
登録日2021-10-28
公開日2023-03-22
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
Nat.Neurosci., 26, 2023
5ZK1
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BU of 5zk1 by Molmil
Crystal Structure of the CRTC2(SeMet)-CREB-CRE complex
分子名称: CREB-regulated transcription coactivator 2, Cyclic AMP-responsive element-binding protein 1, DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), ...
著者Xiang, S, Zhai, L, Valencia-Swain, J.
登録日2018-03-22
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural Insights into the CRTC2-CREB Complex Assembly on CRE.
J. Mol. Biol., 430, 2018
7Y8R
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BU of 7y8r by Molmil
The nucleosome-bound human PBAF complex
分子名称: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ...
著者Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y.
登録日2022-06-24
公開日2022-12-07
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure of nucleosome-bound human PBAF complex.
Nat Commun, 13, 2022
3UGP
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BU of 3ugp by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT)
分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
1BHI
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BU of 1bhi by Molmil
STRUCTURE OF TRANSACTIVATION DOMAIN OF CRE-BP1/ATF-2, NMR, 20 STRUCTURES
分子名称: CRE-BP1
著者Nagadoi, A, Nakazawa, K, Uda, H, Maekawa, T, Ishii, S, Nishimura, Y.
登録日1998-06-09
公開日1999-06-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the transactivation domain of ATF-2 comprising a zinc finger-like subdomain and a flexible subdomain.
J.Mol.Biol., 287, 1999
8HSL
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BU of 8hsl by Molmil
Thermus thermophilus RNA polymerase bound with an inverted Rho hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Murayama, Y, Ehara, H, Sekine, S.
登録日2022-12-19
公開日2023-05-03
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Sci Adv, 9, 2023
3UGO
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BU of 3ugo by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT)
分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
8XVT
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The core subcomplex of human NuA4/TIP60 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y.
登録日2024-01-15
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the human TIP60 complex.
Nat Commun, 15, 2024
5O6B
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Structure of ScPif1 in complex with GGGTTTT and ADP-AlF4
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, DNA (5'-D(*GP*GP*GP*TP*TP*T)-3'), ...
著者Lu, K.Y, Chen, W.F, Rety, S, Liu, N.N, Xu, X.G.
登録日2017-06-06
公開日2017-12-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.029 Å)
主引用文献Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Nucleic Acids Res., 46, 2018
2H27
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Crystal Structure of Escherichia coli SigmaE Region 4 Bound to its-35 Element DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*C*CP*GP*AP*AP*GP*TP*TP*CP*CP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*AP*AP*CP*TP*TP*CP*G)-3', ...
著者Lane, W.J, Darst, S.A.
登録日2006-05-18
公開日2006-08-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structural basis for promoter -35 element recognition by the group IV sigma factors.
Plos Biol., 4, 2006
3B02
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Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8
分子名称: Transcriptional regulator, Crp family
著者Agari, Y, Kuramitsu, S, Shinkai, A, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-06-03
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献X-ray crystal structure of TTHB099, a CRP/FNR superfamily transcriptional regulator from Thermus thermophilus HB8, reveals a DNA-binding protein with no required allosteric effector molecule
Proteins, 80, 2012
5O6D
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BU of 5o6d by Molmil
Structure of ScPif1 in complex with polydT and ATPgS
分子名称: ATP-dependent DNA helicase PIF1, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Lu, K.Y, Chen, W.F, Rety, S, Liu, N.N, Xu, X.G.
登録日2017-06-06
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.283 Å)
主引用文献Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Nucleic Acids Res., 46, 2018
8CXF
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Crystal structure of an i-motif from the HRAS promoter region
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, HRAS DNA
著者Yatsunyk, L.A, Li, K.S.
登録日2022-05-20
公開日2023-05-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal Structure of an i-Motif from the HRAS Oncogene Promoter.
Angew.Chem.Int.Ed.Engl., 62, 2023
8DHC
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Crystal structure of an i-motif from the HRAS promoter region
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, HRAS DNA
著者Yatsunyk, L.A, Li, K.S.
登録日2022-06-27
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal Structure of an i-Motif from the HRAS Oncogene Promoter.
Angew.Chem.Int.Ed.Engl., 62, 2023
8V6V
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Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-12-03
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
3LDA
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Yeast Rad51 H352Y Filament Interface Mutant
分子名称: CHLORIDE ION, DNA repair protein RAD51
著者Villanueva, N.L, Chen, J, Morrical, S.W, Rould, M.A.
登録日2010-01-12
公開日2010-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant.
Nucleic Acids Res., 38, 2010

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