6M84
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![BU of 6m84 by Molmil](/molmil-images/mine/6m84) | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | 著者 | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | 登録日 | 2018-08-21 | 公開日 | 2019-09-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152, 2020
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6M2H
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![BU of 6m2h by Molmil](/molmil-images/mine/6m2h) | A reaction intermediate of sirohydrochlorin nickelochelatase CfbA in complex with Ni2+ and sirohydrochlorin | 分子名称: | 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, NICKEL (II) ION, Sirohydrochlorin cobaltochelatase | 著者 | Fujishiro, T. | 登録日 | 2020-02-27 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis. Chem Sci, 12, 2021
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3ND4
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![BU of 3nd4 by Molmil](/molmil-images/mine/3nd4) | Watson-Crick 16-mer dsRNA | 分子名称: | 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*CP*UP*UP*CP*UP*CP*U)-3', MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Mooers, B.H, Singh, A. | 登録日 | 2010-06-07 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.524 Å) | 主引用文献 | The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate. Rna, 17, 2011
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3QTS
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![BU of 3qts by Molmil](/molmil-images/mine/3qts) | CDK2 in complex with inhibitor RC-2-12 | 分子名称: | Cyclin-dependent kinase 2, [4-amino-2-(phenylamino)-1,3-thiazol-5-yl](3-methoxyphenyl)methanone | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-02-23 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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3QX2
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![BU of 3qx2 by Molmil](/molmil-images/mine/3qx2) | CDK2 in complex with inhibitor KVR-1-190 | 分子名称: | 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-[(2-hydroxyethyl)amino]-5-nitrobenzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-01 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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6M9S
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![BU of 6m9s by Molmil](/molmil-images/mine/6m9s) | Crystal structure of SeMet SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 | 分子名称: | FE (III) ION, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Rohac, R, Mitchell, A.J, Boal, A.K. | 登録日 | 2018-08-24 | 公開日 | 2019-02-06 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. Nature, 566, 2019
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3QWJ
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![BU of 3qwj by Molmil](/molmil-images/mine/3qwj) | CDK2 in complex with inhibitor KVR-1-142 | 分子名称: | 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-chloro-5-nitrobenzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-02-28 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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6M9Z
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![BU of 6m9z by Molmil](/molmil-images/mine/6m9z) | |
3QX4
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![BU of 3qx4 by Molmil](/molmil-images/mine/3qx4) | CDK2 in complex with inhibitor KVR-1-78 | 分子名称: | 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-01 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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3QZI
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![BU of 3qzi by Molmil](/molmil-images/mine/3qzi) | CDK2 in complex with inhibitor KVR-1-126 | 分子名称: | 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyrimidin-5-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-06 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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3QTX
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![BU of 3qtx by Molmil](/molmil-images/mine/3qtx) | CDK2 in complex with inhibitor RC-2-35 | 分子名称: | 4-{[4-amino-5-(3-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-02-23 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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6LK5
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![BU of 6lk5 by Molmil](/molmil-images/mine/6lk5) | MLKL mutant - T357ES358D | 分子名称: | Mixed lineage kinase domain-like protein | 著者 | Wang, H.Y, Li, S, Zhang, Y. | 登録日 | 2019-12-18 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling. Cell Death Dis, 12, 2021
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3RV9
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![BU of 3rv9 by Molmil](/molmil-images/mine/3rv9) | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Ethyl R-Group | 分子名称: | 3-{[(1Z)-1-carboxybut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-05-06 | 公開日 | 2012-05-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
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6LXH
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![BU of 6lxh by Molmil](/molmil-images/mine/6lxh) | Staphylococcus aureus surface protein-sdrc | 分子名称: | Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein | 著者 | Pi, Y, Ji, Q. | 登録日 | 2020-02-11 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural Basis ofStaphylococcus aureusSurface Protein SdrC. Biochemistry, 59, 2020
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3NZM
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3S1H
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![BU of 3s1h by Molmil](/molmil-images/mine/3s1h) | CDK2 in complex with inhibitor RC-2-39 | 分子名称: | 4-{[4-amino-5-(4-methoxybenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-05-15 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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6LVS
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3RV8
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![BU of 3rv8 by Molmil](/molmil-images/mine/3rv8) | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group | 分子名称: | 3-{[(E)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-05-06 | 公開日 | 2012-05-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
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6M12
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![BU of 6m12 by Molmil](/molmil-images/mine/6m12) | Crystal Structure of Rnase L in complex with SU11652 | 分子名称: | 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PHOSPHATE ION, Ribonuclease L, ... | 著者 | Tang, J, Huang, H. | 登録日 | 2020-02-24 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sunitinib inhibits RNase L by destabilizing its active dimer conformation. Biochem.J., 477, 2020
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6M9R
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![BU of 6m9r by Molmil](/molmil-images/mine/6m9r) | |
3RZI
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![BU of 3rzi by Molmil](/molmil-images/mine/3rzi) | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Jiao, W, Jameson, G.B, Hutton, R.D, Parker, E.J. | 登録日 | 2011-05-11 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415, 2012
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6LPD
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![BU of 6lpd by Molmil](/molmil-images/mine/6lpd) | Phascolosoma esculenta | 分子名称: | FE (II) ION, FE (III) ION, Ferritin | 著者 | Su, X.R, Ming, T.H. | 登録日 | 2020-01-09 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta. Febs Open Bio, 11, 2021
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3RW8
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6LSQ
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6M5Z
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![BU of 6m5z by Molmil](/molmil-images/mine/6m5z) | Catalytic domain of GH30 xylanase C from Talaromyces cellulolyticus | 分子名称: | ACETATE ION, GH30 Xylanase C, GLYCEROL, ... | 著者 | Nakamichi, Y, Watanabe, M, Inoue, H. | 登録日 | 2020-03-12 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of GH30-7 endoxylanase C from the filamentous fungus Talaromyces cellulolyticus. Acta Crystallogr.,Sect.F, 76, 2020
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