PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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6M84	Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 分子名称: ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... 著者 Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. 登録日 2018-08-21 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152, 2020
6M2H	A reaction intermediate of sirohydrochlorin nickelochelatase CfbA in complex with Ni2+ and sirohydrochlorin 分子名称: 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, NICKEL (II) ION, Sirohydrochlorin cobaltochelatase 著者 Fujishiro, T. 登録日 2020-02-27 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis. Chem Sci, 12, 2021
3ND4	Watson-Crick 16-mer dsRNA 分子名称: 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*CP*UP*UP*CP*UP*CP*U)-3', MAGNESIUM ION, POTASSIUM ION, ... 著者 Mooers, B.H, Singh, A. 登録日 2010-06-07 公開日 2011-09-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.524 Å) 主引用文献 The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate. Rna, 17, 2011
3QTS	CDK2 in complex with inhibitor RC-2-12 分子名称: Cyclin-dependent kinase 2, [4-amino-2-(phenylamino)-1,3-thiazol-5-yl](3-methoxyphenyl)methanone 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-23 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
3QX2	CDK2 in complex with inhibitor KVR-1-190 分子名称: 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-[(2-hydroxyethyl)amino]-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-01 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
6M9S	Crystal structure of SeMet SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 分子名称: FE (III) ION, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Rohac, R, Mitchell, A.J, Boal, A.K. 登録日 2018-08-24 公開日 2019-02-06 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. Nature, 566, 2019
3QWJ	CDK2 in complex with inhibitor KVR-1-142 分子名称: 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-chloro-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-28 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
6M9Z	X-ray Structure of Branchiostoma floridae fluorescent protein lanFP6G 分子名称: Fluorescent protein lanFP6G 著者 Muslinkina, L, Pletneva, N, Pletnev, V, Pletnev, S. 登録日 2018-08-24 公開日 2019-04-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural Factors Enabling Successful GFP-Like Proteins with Alanine as the Third Chromophore-Forming Residue. J. Mol. Biol., 431, 2019
3QX4	CDK2 in complex with inhibitor KVR-1-78 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-01 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QZI	CDK2 in complex with inhibitor KVR-1-126 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyrimidin-5-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-06 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QTX	CDK2 in complex with inhibitor RC-2-35 分子名称: 4-{[4-amino-5-(3-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-23 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
6LK5	MLKL mutant - T357ES358D 分子名称: Mixed lineage kinase domain-like protein 著者 Wang, H.Y, Li, S, Zhang, Y. 登録日 2019-12-18 公開日 2020-12-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling. Cell Death Dis, 12, 2021
3RV9	Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Ethyl R-Group 分子名称: 3-{[(1Z)-1-carboxybut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI 著者 Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
6LXH	Staphylococcus aureus surface protein-sdrc 分子名称: Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein 著者 Pi, Y, Ji, Q. 登録日 2020-02-11 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural Basis ofStaphylococcus aureusSurface Protein SdrC. Biochemistry, 59, 2020
3NZM	Crystal structure of DNAE intein with N-extein in redox trap 分子名称: DNA polymerase III subunit alpha, SULFATE ION 著者 Van Roey, P, Belfort, M, Callahan, B.P. 登録日 2010-07-16 公開日 2011-06-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications. Nat.Struct.Mol.Biol., 18, 2011
3S1H	CDK2 in complex with inhibitor RC-2-39 分子名称: 4-{[4-amino-5-(4-methoxybenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-05-15 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
6LVS	USP14 catalytic domain mutant C114S 分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, FORMIC ACID, ... 著者 Lin, H.C, Lin, T.H, Chou, C.Y. 登録日 2020-02-04 公開日 2020-03-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 USP14 catalytic domain mutant C114S To Be Published
3RV8	Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group 分子名称: 3-{[(E)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI 著者 Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
6M12	Crystal Structure of Rnase L in complex with SU11652 分子名称: 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PHOSPHATE ION, Ribonuclease L, ... 著者 Tang, J, Huang, H. 登録日 2020-02-24 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Sunitinib inhibits RNase L by destabilizing its active dimer conformation. Biochem.J., 477, 2020
6M9R	Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 with a bound N(delta)-hydroxy-N(omega)-methyl-L-arginine intermediate 分子名称: (2S)-2-amino-5-{[(E)-amino(methylamino)methylidene](hydroxy)azaniumyl}pentanoate, FE (III) ION, SznF 著者 Rohac, R, Mitchell, A.J, Boal, A.K. 登録日 2018-08-24 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. Nature, 566, 2019
3RZI	The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan 分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Jiao, W, Jameson, G.B, Hutton, R.D, Parker, E.J. 登録日 2011-05-11 公開日 2012-01-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415, 2012
6LPD	Phascolosoma esculenta 分子名称: FE (II) ION, FE (III) ION, Ferritin 著者 Su, X.R, Ming, T.H. 登録日 2020-01-09 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta. Febs Open Bio, 11, 2021
3RW8	Crystal structure of lysozyme in 40% ethanol 分子名称: ACETATE ION, CHLORIDE ION, ETHANOL, ... 著者 Sharma, P, Solanki, A.K, Ashish 登録日 2011-05-08 公開日 2011-05-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.855 Å) 主引用文献 Crystal structure of lysozyme in 40% ethanol to be published
6LSQ	Crystal structure of Echistatin, an RGD-containing short disintegrin 分子名称: Disintegrin, SULFATE ION 著者 Chang, Y.T, Chen, Y.C, Chuang, W.J. 登録日 2020-01-19 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin. Toxins, 12, 2020
6M5Z	Catalytic domain of GH30 xylanase C from Talaromyces cellulolyticus 分子名称: ACETATE ION, GH30 Xylanase C, GLYCEROL, ... 著者 Nakamichi, Y, Watanabe, M, Inoue, H. 登録日 2020-03-12 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of GH30-7 endoxylanase C from the filamentous fungus Talaromyces cellulolyticus. Acta Crystallogr.,Sect.F, 76, 2020

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