6M9R
Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 with a bound N(delta)-hydroxy-N(omega)-methyl-L-arginine intermediate
Summary for 6M9R
Entry DOI | 10.2210/pdb6m9r/pdb |
Related | 6M9S |
Descriptor | SznF, (2S)-2-amino-5-{[(E)-amino(methylamino)methylidene](hydroxy)azaniumyl}pentanoate, FE (III) ION, ... (4 entities in total) |
Functional Keywords | non-heme iron-dependent, cupin domain, helix bundle, monooxygenase, n-nitrosation, l-arginine derivative, metal-bound, ligand-bound, anaerobic, oxidoreductase |
Biological source | Streptomyces achromogenes subsp. streptozoticus |
Total number of polymer chains | 2 |
Total formula weight | 108262.51 |
Authors | Rohac, R.,Mitchell, A.J.,Boal, A.K. (deposition date: 2018-08-24, release date: 2019-02-06, Last modification date: 2023-10-11) |
Primary citation | Ng, T.L.,Rohac, R.,Mitchell, A.J.,Boal, A.K.,Balskus, E.P. An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. Nature, 566:94-99, 2019 Cited by PubMed: 30728519DOI: 10.1038/s41586-019-0894-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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