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6M9R

Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 with a bound N(delta)-hydroxy-N(omega)-methyl-L-arginine intermediate

Summary for 6M9R
Entry DOI10.2210/pdb6m9r/pdb
Related6M9S
DescriptorSznF, (2S)-2-amino-5-{[(E)-amino(methylamino)methylidene](hydroxy)azaniumyl}pentanoate, FE (III) ION, ... (4 entities in total)
Functional Keywordsnon-heme iron-dependent, cupin domain, helix bundle, monooxygenase, n-nitrosation, l-arginine derivative, metal-bound, ligand-bound, anaerobic, oxidoreductase
Biological sourceStreptomyces achromogenes subsp. streptozoticus
Total number of polymer chains2
Total formula weight108262.51
Authors
Rohac, R.,Mitchell, A.J.,Boal, A.K. (deposition date: 2018-08-24, release date: 2019-02-06, Last modification date: 2023-10-11)
Primary citationNg, T.L.,Rohac, R.,Mitchell, A.J.,Boal, A.K.,Balskus, E.P.
An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin.
Nature, 566:94-99, 2019
Cited by
PubMed: 30728519
DOI: 10.1038/s41586-019-0894-z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.69 Å)
Structure validation

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