PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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5NCT	Structure of the trypsin induced serpin-type proteinase inhibitor, miropin. 分子名称: ASPARTIC ACID, GLYCEROL, SERINE, ... 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5NCU	Structure of the subtilisin induced serpin-type proteinase inhibitor, miropin. 分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ... 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5DBQ	Crystal structure of insect thioredoxin at 1.95 Angstroms 分子名称: Thioredoxin 著者 Klinke, S, Tejedor, M.D, Cerutti, M.L, Giacometti, R, Otero, L.H, Goldbaum, F.A, Zavala, J.A, Wolosiuk, R.A, Pagano, E.A. 登録日 2015-08-21 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of insect thioredoxin at 1.95 Angstroms To Be Published
5NGH	Structure of Odorant Binding Protein 3 from Giant Panda (Ailuropoda melanoleuca) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Odorant Binding Protein 3 著者 Cambillau, C, Spinelli, S, Pelosi, P. 登録日 2017-03-17 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8HGZ	Crystal structure of insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2022-11-16 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
5NOJ	Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "OPEN" state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Risi, C, Eisner, J, Belknap, B, Heeley, D.H, White, H.D, Schroeder, G.F, Galkin, V.E. 登録日 2017-04-12 公開日 2017-08-02 最終更新日 2017-08-09 実験手法 ELECTRON MICROSCOPY (11 Å) 主引用文献 Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NP5	Abl2 SH3 pTyr116/161 分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION 著者 Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. 登録日 2017-04-13 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5DGW	Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand 分子名称: (3R,3aS,4S,7aS)-3-(ethylamino)hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Pol protein, ... 著者 Agniswamy, J, Wang, Y.-F, Weber, I.T. 登録日 2015-08-28 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands. Org.Biomol.Chem., 13, 2015
5D8J	Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes. 分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ... 著者 Doyle, C, Birrane, G. 登録日 2015-08-17 公開日 2016-01-13 最終更新日 2017-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015
5D0J	Grb7 SH2 with inhibitor peptide 分子名称: G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION 著者 Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J. 登録日 2015-08-03 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6, 2016
5NA9	The X-ray structure of bovine pancreatic ribonuclease incubated in the presence of an excess of carboplatin (1:10 ratio) 分子名称: CESIUM ION, CHLORIDE ION, Ribonuclease pancreatic, ... 著者 Ferraro, G, Merlino, A. 登録日 2017-02-27 公開日 2017-08-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin. J. Inorg. Biochem., 173, 2017
5N8M	Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex A) 分子名称: RISC-loading complex subunit TARBP2, RNA (5'-R(*GP*UP*AP*CP*GP*GP*AP*AP*UP*AP*GP*AP*UP*AP*AP*UP*UP*AP*AP*UP*U)-3'), RNA (5'-R(*UP*UP*AP*AP*UP*UP*AP*UP*CP*UP*AP*UP*UP*CP*CP*GP*UP*AP*CP*UP*U)-3') 著者 Masliah, G, Maris, C, Allain, H.-T.F. 登録日 2017-02-23 公開日 2018-02-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains. EMBO J., 37, 2018
5NCB	Crystal structure of Amycolatopsis cytochrome P450 GcoA in complex with guaiacol. 分子名称: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE 著者 Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. 登録日 2017-03-03 公開日 2018-07-04 最終更新日 2022-03-30 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun, 9, 2018
8JUV	Crystal structure of a receptor like kinase with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, LRR receptor-like serine/threonine-protein kinase FLS2, MAGNESIUM ION 著者 Ming, Z, Zhao, Q. 登録日 2023-06-27 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 An active State Formation Mechanism of Receptor Kinase in Plant Plant Commun., 2024
5DET	X-ray structure of human RBPMS in complex with the RNA 分子名称: RNA (5'-R(*UP*CP*AP*C)-3'), RNA (5'-R(P*UP*CP*AP*CP*U)-3'), RNA-binding protein with multiple splicing, ... 著者 Teplova, M, Farazi, T.A, Tuschl, T, Patel, D.J. 登録日 2015-08-25 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Q. Rev. Biophys., 49, 2016
5NB8	Structure of vWC domain from CCN3 分子名称: GLYCEROL, IMIDAZOLE, Protein NOV homolog 著者 Xu, E.-R, Hyvonen, M. 登録日 2017-03-01 公開日 2017-06-14 最終更新日 2017-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2. J. Biol. Chem., 292, 2017
5NBM	Crystal structure of the Arp4-N-actin(ATP-state) heterodimer bound by a nanobody 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... 著者 Knoll, K.R, Eustermann, S, Hopfner, K.P. 登録日 2017-03-02 公開日 2018-08-22 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling. Nat. Struct. Mol. Biol., 25, 2018
5B30	H-Ras WT in complex with GppNHp (state 1) after structural transition by humidity control 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Kumasaka, T, Miyano, N, Baba, S, Matsumoto, S, Kataoka, T, Shima, F. 登録日 2016-02-08 公開日 2016-06-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular Mechanism for Conformational Dynamics of Ras-GTP Elucidated from In-Situ Structural Transition in Crystal Sci Rep, 6, 2016
5N6O	Wild type human Rac1-GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 著者 Cherfils, J, Ferrandez, Y. 登録日 2017-02-15 公開日 2017-12-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. Sci Rep, 7, 2017
8ODX	Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and VHH. 分子名称: FAb4 Heavy chain, FAb4 Light chain, Interleukin-12 receptor subunit beta-1, ... 著者 Bloch, Y, Savvides, S.N. 登録日 2023-03-09 公開日 2024-02-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
8KDX	Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current 分子名称: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn 著者 Padavattan, S, Jos, S. 登録日 2023-08-10 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.01 Å) 主引用文献 Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current. J.Mol.Biol., 436, 2024
5N4M	Human myelin protein P2, mutant I43N 分子名称: D-MALATE, Myelin P2 protein, PALMITIC ACID, ... 著者 Ruskamo, S, Kursula, P. 登録日 2017-02-11 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. Sci Rep, 7, 2017
5N4P	Human myelin P2, mutant I52T 分子名称: D-MALATE, Myelin P2 protein, PALMITIC ACID, ... 著者 Ruskamo, S, Kursula, P. 登録日 2017-02-11 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.533 Å) 主引用文献 Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. Sci Rep, 7, 2017
8OIL	Plasmodium falciparum circumsporozoite protein C-terminal domain 分子名称: Circumsporozoite protein 著者 Sterckx, Y.G.-J, Volkov, A.N, Geens, R. 登録日 2023-03-23 公開日 2024-02-28 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 Plasmodium falciparum circumsporozoite protein C-terminal domain To Be Published
5APR	STRUCTURES OF COMPLEXES OF RHIZOPUSPEPSIN WITH PEPSTATIN AND OTHER STATINE-CONTAINING INHIBITORS 分子名称: CALCIUM ION, PEPSTATIN-LIKE RENIN INHIBITOR, RHIZOPUSPEPSIN 著者 Suguna, K, Davies, D.R. 登録日 1989-08-03 公開日 1991-04-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of complexes of rhizopuspepsin with pepstatin and other statine-containing inhibitors. Proteins, 13, 1992

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