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3LKQ
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Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1977 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LI4
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BU of 3li4 by Molmil
Diisopropyl fluorophosphatase (DFPase), N120D,N175D,D229N mutant
分子名称: CALCIUM ION, Diisopropyl-fluorophosphatase
著者Chen, J.C.-H.
登録日2010-01-24
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes.
Chem.Biol.Interact, 187, 2010
3L9J
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BU of 3l9j by Molmil
Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
分子名称: MAGNESIUM ION, TNFalpha, Tumor necrosis factor, ...
著者Byla, P, Andersen, M.H, Thogersen, H.C, Gad, H.H, Hartmann, R.
登録日2010-01-05
公開日2010-02-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex
J.Biol.Chem., 285, 2010
3LM1
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BU of 3lm1 by Molmil
Crystal Structure Analysis of Maclura pomifera agglutinin complex with p-nitrophenyl-GalNAc
分子名称: 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Agglutinin alpha chain, Agglutinin beta-2 chain
著者Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M.
登録日2010-01-29
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses.
Glycobiology, 20, 2010
3LMP
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BU of 3lmp by Molmil
Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator
分子名称: (9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-N-(1-naphthylmethyl)-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peptide of Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者Matsui, Y, Hanzawa, H.
登録日2010-01-31
公開日2010-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives
Bioorg.Med.Chem.Lett., 20, 2010
3LMZ
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BU of 3lmz by Molmil
Crystal structure of Putative sugar isomerase. (YP_001305105.1) from Parabacteroides distasonis ATCC 8503 at 1.44 A resolution
分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, Putative sugar isomerase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-02-01
公開日2010-02-23
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Crystal structure of Putative sugar isomerase. (YP_001305105.1) from Parabacteroides distasonis ATCC 8503 at 1.44 A resolution
To be published
3L5E
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BU of 3l5e by Molmil
Structure of BACE Bound to SCH736062
分子名称: (4S)-1-(4-{[(2Z,4R)-4-(2-cyclohexylethyl)-4-(cyclohexylmethyl)-2-imino-5-oxoimidazolidin-1-yl]methyl}benzyl)-4-propylimidazolidin-2-one, Beta-secretase 1, D(-)-TARTARIC ACID
著者Strickland, C, Zhu, Z.
登録日2009-12-21
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation
J.Med.Chem., 53, 2010
3LF1
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Apo structure of The Short Chain Oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 Containing an Atypical Catalytic Center
分子名称: CHLORIDE ION, MANGANESE (II) ION, Short Chain Oxidoreductase Q9HYA2
著者Huether, R, Umland, T.C, Duax, W.L.
登録日2010-01-15
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献The short-chain oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 contains an atypical catalytic center.
Protein Sci., 19, 2010
3LGM
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BU of 3lgm by Molmil
Crystal structure of reduced IsdI in complex with heme
分子名称: Heme-degrading monooxygenase isdI, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Ukpabi, G.N, Murphy, M.E.P.
登録日2010-01-20
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The IsdG-family of haem oxygenases degrades haem to a novel chromophore
Mol.Microbiol., 75, 2010
3LGR
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BU of 3lgr by Molmil
Xylanase II from Trichoderma reesei cocrystallized with tris-dipicolinate europium
分子名称: EUROPIUM ION, Endo-1,4-beta-xylanase 2, PYRIDINE-2,6-DICARBOXYLIC ACID
著者Pompidor, G, Kahn, R, Maury, O.
登録日2010-01-21
公開日2011-01-19
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction.
Acta Crystallogr.,Sect.D, 66, 2010
3L6X
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BU of 3l6x by Molmil
Crystal structure of p120 catenin in complex with E-cadherin
分子名称: Catenin delta-1, E-cadherin, SULFATE ION
著者Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M.
登録日2009-12-27
公開日2010-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
3L7A
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BU of 3l7a by Molmil
Crystal Structure of Glycogen Phosphorylase DK2 complex
分子名称: 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one, Glycogen phosphorylase, muscle form
著者Tsirkone, V.G, Lamprakis, C, Hayes, J.M, Skamnaki, V, Drakou, C, Zographos, S.E, Leonidas, D.D.
登録日2009-12-28
公開日2010-10-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
3LI3
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BU of 3li3 by Molmil
Diisopropyl fluorophosphatase (DFPase), D121E mutant
分子名称: CALCIUM ION, Diisopropyl-fluorophosphatase
著者Chen, J.C.-H.
登録日2010-01-24
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes.
Chem.Biol.Interact, 187, 2010
3LLE
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BU of 3lle by Molmil
X-ray structure of bovine SC0322,Ca(2+)-S100B
分子名称: 13-methyl-13,14-dihydro[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine, CALCIUM ION, Protein S100-B
著者Charpentier, T.H, Weber, D.J, Wilder, P.W.
登録日2010-01-28
公開日2010-12-29
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.
Int.J.High Throughput Screen, 2010, 2010
3LLO
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BU of 3llo by Molmil
Crystal structure of the STAS domain of motor protein prestin (anion transporter SLC26A5)
分子名称: Prestin, octyl beta-D-glucopyranoside
著者Pasqualetto, E, Aiello, R, Bonetto, G, Battistutta, R.
登録日2010-01-29
公開日2010-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure of the cytosolic portion of the motor protein prestin and functional role of the STAS domain in SLC26/SulP anion transporters.
J.Mol.Biol., 400, 2010
3LKN
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BU of 3lkn by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LKY
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BU of 3lky by Molmil
Monomeric Griffithsin with a Single Gly-Ser Insertion
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
3L5I
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BU of 3l5i by Molmil
Crystal structure of FnIII domains of human GP130 (Domains 4-6)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-6 receptor subunit beta
著者Kershaw, N.J, Zhang, J.-G, Garrett, T.P.J, Czabotar, P.E.
登録日2009-12-22
公開日2010-05-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
3LL2
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Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
3L5R
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BU of 3l5r by Molmil
Crystal structure of macrophage migration inhibitory factor (MIF) with phenylchromenone inhibitor at 1.94A resolution
分子名称: 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, GLYCEROL, Macrophage migration inhibitory factor, ...
著者McLean, L, Zhang, Y.
登録日2009-12-22
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site.
Bioorg.Med.Chem.Lett., 20, 2010
3LLT
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BU of 3llt by Molmil
Crystal structure of PF14_0431, kinase domain.
分子名称: ACETATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
著者Wernimont, A.K, Tempel, W, Lin, Y.H, Loppnau, P, MacKenzie, F, Sullivan, H, Weadge, J, Kozieradzki, I, Cossar, D, Sinesterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Qiu, W, Hutchinson, A, Structural Genomics Consortium (SGC)
登録日2010-01-29
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
3LMX
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Tyrosine 447 of Protocatechuate 34,-Dioxygenase Controls Efficient Progress Through Catalysis
分子名称: 3,4-DIHYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Purpero, V.M, Lipscomb, J.D, Shi, K.
登録日2010-02-01
公開日2011-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tyrosine 447 of Protocatechuate 34,-Dioxygenase Controls Efficient Progress Through Catalysis
To be Published
3LNQ
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Structure of Aristaless homeodomain in complex with DNA
分子名称: 5'-D(*CP*CP*CP*TP*AP*AP*TP*TP*AP*AP*AP*CP*CP*C)-3', 5'-D(*GP*GP*GP*TP*TP*TP*AP*AP*TP*TP*AP*GP*GP*G)-3', ACETATE ION, ...
著者Takamura, Y, Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M.
登録日2010-02-02
公開日2010-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless
Embo J., 29, 2010
3LA6
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BU of 3la6 by Molmil
Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Tyrosine-protein kinase wzc
著者Gruszczyk, J, Nessler, S, Gueguen-Chaignon, V, Vigouroux, A, Bechet, E, Grangeasse, C.
登録日2010-01-06
公開日2010-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export
Mol.Microbiol., 77, 2010
3LNX
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Second PDZ domain from human PTP1E
分子名称: IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13
著者Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2010-02-03
公開日2010-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.642 Å)
主引用文献Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010

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