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7T18
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Rev1 Ternary Complex with dTTP and Ca2+
分子名称: CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*G)-3'), ...
著者Freudenthal, B.D, Weaver, T.M.
登録日2021-12-01
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Nat Commun, 13, 2022
7Q8S
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BU of 7q8s by Molmil
Leishmania major ADP-actin filament decorated with Leishmania major cofilin
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ...
著者Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T.
登録日2021-11-11
公開日2022-05-18
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
Nat Commun, 13, 2022
7T1A
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BU of 7t1a by Molmil
Rev1 Ternary Complex with dATP and Ca2+
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ...
著者Freudenthal, B.D, Weaver, T.M.
登録日2021-12-01
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Nat Commun, 13, 2022
6KW4
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BU of 6kw4 by Molmil
The ClassB RSC-Nucleosome Complex
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
著者Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
登録日2019-09-06
公開日2019-11-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (7.55 Å)
主引用文献Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
7W0E
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BU of 7w0e by Molmil
dmDicer2-LoqsPD-dsRNA Active-dicing status
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0B
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Dicer2-LoqsPD complex at apo status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0A
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dmDicer2-LoqsPD-dsRNA Dimer status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
1PHH
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BU of 1phh by Molmil
CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE
分子名称: 3,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
著者Schreuder, H.A, Drenth, J.
登録日1987-11-04
公開日1988-04-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate.
J.Mol.Biol., 199, 1988
7W93
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Crystal structure of E.coli pseudouridine kinase PsuK complexed with N1-methyl-pseudouridine
分子名称: 5-[(2S,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-pyrimidine-2,4-dione, POTASSIUM ION, PfkB domain protein
著者Li, K.J, Li, X.J, Wu, B.X.
登録日2021-12-09
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK.
Front Microbiol, 13, 2022
7SPL
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BU of 7spl by Molmil
[2T3] Self-assembling 3D DNA triangle with three inter-junction base pairs containing the L1 junction and a zero-linked center strand
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (5'-D(*GP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*CP*C)-3'), ...
著者Vecchioni, S, Lu, B, Sha, R, Ohayon, Y.P, Seeman, N.C.
登録日2021-11-02
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (6.09 Å)
主引用文献The Rule of Thirds: Controlling Junction Chirality and Polarity in 3D DNA Tiles.
Small, 19, 2023
5FFO
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BU of 5ffo by Molmil
Integrin alpha V beta 6 in complex with pro-TGF-beta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dong, X, Zhao, B, Springer, T.A.
登録日2015-12-18
公開日2017-01-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
8JND
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BU of 8jnd by Molmil
The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNE
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BU of 8jne by Molmil
The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.68 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNF
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The cryo-EM structure of the RAD51 filament bound to the nucleosome
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.91 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
4YH8
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BU of 4yh8 by Molmil
Structure of yeast U2AF complex
分子名称: Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ZINC ION
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2015-02-27
公開日2015-08-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.
Genes Dev., 29, 2015
7F9X
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BU of 7f9x by Molmil
Structure of the second OTU domain of LotA
分子名称: LotA
著者Iwai, T, Takekawa, T, Kubori, T, Nagai, H, Imada, K.
登録日2021-07-05
公開日2021-10-20
最終更新日2022-02-23
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Basis of Ubiquitin Recognition by a Bacterial Ovarian Tumor Deubiquitinase LotA.
J.Bacteriol., 204, 2022
7EQX
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BU of 7eqx by Molmil
Crystal structure of an Aedes aegypti procarboxypeptidase B1
分子名称: Carboxypeptidase B, ZINC ION
著者Choong, Y.K, Gavor, E, Jobichen, C, Sivaraman, J.
登録日2021-05-05
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection.
Life Sci Alliance, 5, 2022
4PI3
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BU of 4pi3 by Molmil
Crystal structure analysis of cruzain bound to vinyl sulfone analog of WRR-483 (WRR-666)
分子名称: Cruzipain, N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide
著者Tochowicz, A, McKerrow, J.H.
登録日2014-05-08
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain.
Acs Med.Chem.Lett., 7, 2016
7TVD
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BU of 7tvd by Molmil
Crystal structure of the kinase domain of EGFR exon-19 (del-747-749) mutant
分子名称: Epidermal growth factor receptor
著者Ashtekar, K.D, Stayrook, S.E, Lemmon, M.A.
登録日2022-02-04
公開日2022-02-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations.
Nat Commun, 13, 2022
4WEV
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BU of 4wev by Molmil
Crystal structure of human AKR1B10 complexed with NADP+ and sulindac
分子名称: Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
著者Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Crespo, I, Porte, S, Pares, X, Farres, J, Podjarny, A.
登録日2014-09-11
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.453 Å)
主引用文献Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Chem.Biol.Interact., 234, 2015
7WKP
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BU of 7wkp by Molmil
ICP1 Csy4
分子名称: 3' stem loop crRNA, Csy4
著者Zhang, M, Peng, R.
登録日2022-01-10
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
7WKO
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BU of 7wko by Molmil
ICP1 Csy1-2 complex
分子名称: Csy1, Csy2
著者Zhang, M, Peng, R.
登録日2022-01-10
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XB5
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BU of 7xb5 by Molmil
Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme
分子名称: fusion protein of Sterol uptake control protein 2 and Endolysin
著者Tan, L, Im, Y.J.
登録日2022-03-20
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.44 Å)
主引用文献Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
7EWF
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BU of 7ewf by Molmil
Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
分子名称: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
著者Kuang, Z, Niu, L.
登録日2021-05-25
公開日2022-09-07
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
7EWM
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Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
分子名称: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
著者Kuang, Z, Niu, L.
登録日2021-05-25
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022

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件を2024-08-14に公開中

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