PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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8JOO	Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate ikarugamycin 分子名称: (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450, FORMIC ACID, ... 著者 Zhang, Y.L, Zhang, L.P, Zhang, C.S. 登録日 2023-06-08 公開日 2023-11-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
5CNB	Ultrafast dynamics in myoglobin: 0.5 ps time delay 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K.J, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M.C, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. 登録日 2015-07-17 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
5CO1	Crystal Structure of Zebrafish Protocadherin-19 EC3-4 分子名称: CALCIUM ION, Protocadherin-19 isoform 1 著者 Cooper, S.R, Jontes, J.D, Sotomayor, M. 登録日 2015-07-19 公開日 2016-11-02 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy. Elife, 5, 2016
8JNO	Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-deOH-HSAF 分子名称: (1Z,3E,5S,7S,8R,9S,10S,11R,13R,15R,16S,18Z,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhang, Y.L, Zhang, L.P, Zhang, C.S. 登録日 2023-06-06 公開日 2023-11-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
5C9M	The structure of oxidized rat cytochrome c (T28A) at 1.362 angstroms resolution. 分子名称: Cytochrome c, somatic, HEME C, ... 著者 Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M. 登録日 2015-06-28 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.362 Å) 主引用文献 The structure of oxidized rat cytochrome c (T28A) at 1.362 angstroms resolution. To Be Published
5MRR	Crystal structure of L1 protease of Lysobacter sp. XL1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... 著者 Gabdulkhakov, A, Tishchenko, S, Lisov, A, Leontievsky, A. 登録日 2016-12-26 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of L1 protease of Lysobacter sp. XL1 To Be Published
5MVY	Thin Filament at low calcium concentration 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle 著者 Paul, D.M, Squire, J.M, Morris, E.P. 登録日 2017-01-17 公開日 2018-02-14 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (28.4 Å) 主引用文献 Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism. J. Struct. Biol., 197, 2017
5MT0	COMPLEMENT FACTOR D IN COMPLEX WITH A REVERSIBLE INDOLE CARBOXYLIC ACID BASED INHIBITOR 分子名称: 5-fluoranyl-3-[[(1~{S},2~{S})-2-phenylcyclopropyl]carbonylamino]-1~{H}-indole-2-carboxylic acid, Complement factor D, SULFATE ION 著者 Mac Sweeney, A, Ostermann, N. 登録日 2017-01-06 公開日 2017-02-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors. J. Med. Chem., 60, 2017
5CNG	ultrafast dynamics in myoglobin: 150 ps time delay 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. 登録日 2015-07-17 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
5CMD	Oligomer crystal structure of CC chemokine 5 (CCL5) 分子名称: C-C motif chemokine 5, SULFATE ION 著者 Liang, W.G, Tang, W.-J. 登録日 2015-07-16 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.086 Å) 主引用文献 Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
5C8W	PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, MALONIC ACID, SODIUM ION, ... 著者 Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W. 登録日 2015-06-26 公開日 2016-01-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II. J.Biol.Chem., 291, 2016
5MS4	Kallikrein-related peptidase 8 leupeptin inhibitor complex 分子名称: CALCIUM ION, Kallikrein-8, LEUPEPTIN, ... 著者 Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. 登録日 2016-12-30 公開日 2018-01-17 最終更新日 2019-10-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8, 2018
5CN9	Ultrafast dynamics in myoglobin: 0.4 ps time delay 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K.J, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M.C, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. 登録日 2015-07-17 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
5CO2	Crystalization of human zinc insulin at pH 5.5 分子名称: CHLORIDE ION, Insulin, ZINC ION 著者 Lima, L.M.T.R, Palmieri, L.C. 登録日 2015-07-19 公開日 2015-08-26 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human zinc insulin at pH 5.5 To Be Published
5MNL	Cationic trypsin in complex with benzylamine (deuterated sample at 295 K) 分子名称: BENZYLAMINE, CALCIUM ION, Cationic trypsin, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-12-13 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.039 Å) 主引用文献 Cationic trypsin in complex with benzylamine (deuterated sample at 295 K) to be published
5MNV	Structural and functional characterization of OleP in complex with 6DEB in PEG 分子名称: 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE 著者 Parisi, G, Savino, C, Montemiglio, L.C. 登録日 2016-12-13 公開日 2018-02-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Substrate-induced conformational change in cytochrome P450 OleP. FASEB J., 33, 2019
5MOO	Joint X-ray/neutron structure of cationic trypsin in complex with aniline 分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ... 著者 Schiebel, J, Schrader, T.E, Ostermann, A, Heine, A, Klebe, G. 登録日 2016-12-14 公開日 2017-05-24 最終更新日 2024-05-01 実験手法 NEUTRON DIFFRACTION (1.441 Å), X-RAY DIFFRACTION 主引用文献 Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and 2-Aminopyridine Become Protonated Upon Binding to Trypsin. Angew. Chem. Int. Ed. Engl., 56, 2017
5C98	1.45A resolution structure of SRPN18 from Anopheles gambiae 分子名称: AGAP007691-PB 著者 Lovell, S, Battaile, K.P, Gulley, M, Zhang, X, Meekins, D.A, Gao, F.P, Michel, K. 登録日 2015-06-26 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae. Acta Crystallogr F Struct Biol Commun, 72, 2016
5MT9	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-07 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
8JGD	GDP-bound KRAS G12C in complex with YK-8S 分子名称: (2~{S})-1-[4-[7-(8-ethynyl-7-fluoranyl-naphthalen-1-yl)-8-fluoranyl-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]-2-oxidanyl-propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Zhang, Z.M, Wang, R.L. 登録日 2023-05-20 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.60037053 Å) 主引用文献 Simultaneous Covalent Modification of K-Ras(G12D) and K-Ras(G12C) with Tunable Oxirane Electrophiles. J.Am.Chem.Soc., 145, 2023
8JHL	GDP-bound KRAS G12D in complex with YK-8S 分子名称: 1-[4-[7-(8-ethynyl-7-fluoranyl-naphthalen-1-yl)-8-fluoranyl-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]-3-oxidanyl-propan-1-one, GTPase KRas, N-terminally processed, ... 著者 Zhang, Z.M, Wang, R.L. 登録日 2023-05-23 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.10004044 Å) 主引用文献 Simultaneous Covalent Modification of K-Ras(G12D) and K-Ras(G12C) with Tunable Oxirane Electrophiles. J.Am.Chem.Soc., 145, 2023
5CHY	STRUCTURE OF CHEMOTAXIS PROTEIN CHEY 分子名称: CALCIUM ION, CHEY 著者 Zhu, X, Rebello, J, Matsumura, P, Volz, K. 登録日 1996-08-29 公開日 1996-12-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of CheY mutants Y106W and T87I/Y106W. CheY activation correlates with movement of residue 106. J.Biol.Chem., 272, 1997
5MT3	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-06 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5CIW	Ran GDP Y39A mutant monoclinic crystal form 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Vetter, I.R, Brucker, S. 登録日 2015-07-13 公開日 2015-09-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy. J.Biol.Chem., 290, 2015
5MT4	COMPLEMENT FACTOR D IN COMPLEX WITH A REVERSIBLE BENZOIC ACID BASED INHIBITOR 分子名称: 2-[(phenylmethyl)carbamoylamino]benzoic acid, Complement factor D 著者 Mac Sweeney, A, Ostermann, N. 登録日 2017-01-06 公開日 2017-02-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors. J. Med. Chem., 60, 2017

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