PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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8OIS	28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 28S ribosomal protein S10, mitochondrial, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OG7	70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. 登録日 2019-04-01 公開日 2019-09-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
8I0V	The cryo-EM structure of human post-Bact complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0W	The cryo-EM structure of human C complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0T	The cryo-EM structure of human Bact-III complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
6OVY	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2019-05-08 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OVR	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2019-05-08 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.843 Å) 主引用文献 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
8JJR	Cryo-EM structure of Symbiodinium photosystem I 分子名称: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Zhao, L.S, Wang, N, Li, K, Zhang, Y.Z, Liu, L.N. 登録日 2023-05-31 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Architecture of symbiotic dinoflagellate photosystem I-light-harvesting supercomplex in Symbiodinium. Nat Commun, 15, 2024
6Q13	CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, ... 著者 Davies, D.R, Dranow, D.M. 登録日 2019-08-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J.Med.Chem., 63, 2020
8KI3	Structure of the human ATP synthase bound to bedaquiline (composite) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... 著者 Lai, Y, Zhang, Y, Gong, H. 登録日 2023-08-22 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of Mycobacterium tuberculosis ATP synthase To Be Published
8E5T	Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... 著者 Sanghai, Z.A, Piwowarczyk, R, Vanden Broeck, A, Klinge, S. 登録日 2022-08-22 公開日 2023-04-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation. Nat.Struct.Mol.Biol., 30, 2023
8OJP	Human galectin 1 in complex with inhibitor 分子名称: (2~{R},3~{R},4~{S},5~{R},6~{R})-2-[3,5-bis(chloranyl)-4-fluoranyl-phenyl]sulfanyl-6-(hydroxymethyl)-4-[4-(1,3-thiazol-2-yl)-1,2,3-triazol-1-yl]oxane-3,5-diol, GLYCEROL, Galectin-1 著者 Hakansson, M, Diehl, C, Nilsson, U.J, Zetterberg, F.R, Peterson, K. 登録日 2023-03-24 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Discovery of Selective and Orally Available Galectin-1 Inhibitors. J.Med.Chem., 66, 2023
6QC6	Ovine respiratory complex I FRC open class 1 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-27 公開日 2019-08-21 最終更新日 2019-10-02 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
6QIK	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Kargas, V, Warren, A.J. 登録日 2019-01-20 公開日 2019-06-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanism of completion of peptidyltransferase centre assembly in eukaryotes. Elife, 8, 2019
8IVW	Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment 分子名称: Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 著者 Geng, Y, Zhai, L. 登録日 2023-03-29 公開日 2023-07-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.205 Å) 主引用文献 Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
6QC9	Ovine respiratory complex I FRC open class 4 分子名称: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-27 公開日 2019-08-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
8IYJ	Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm 分子名称: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... 著者 Zhou, L.N, Gui, M, Wu, J.P. 登録日 2023-04-05 公開日 2023-07-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell, 186, 2023
6QCA	Ovine respiratory complex I FRC open class 5 分子名称: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-27 公開日 2019-08-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
6QC3	Ovine respiratory supercomplex I+III2 open class 1 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-26 公開日 2019-08-21 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
8IPX	human nuclear pre-60S ribosomal particle - State C' 分子名称: 28S rRNA, 5.8S rRNA, 5S RNA, ... 著者 Zhang, Y, Gao, N. 登録日 2023-03-15 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8IPY	human nuclear pre-60S ribosomal particle - State D' 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Zhang, Y, Gao, N. 登録日 2023-03-15 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8INK	human nuclear pre-60S ribosomal particle - State D 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Zhang, Y, Gao, N. 登録日 2023-03-10 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
8K2D	Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A 分子名称: 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... 著者 Buschauer, R, Beckmann, R, Cheng, J. 登録日 2023-07-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8EEY	Cas7-11 in complex with DR-mismatched target RNA, Csx29 and Csx30 分子名称: Cas7-11, Csx29, Csx30, ... 著者 Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. 登録日 2022-09-07 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.53 Å) 主引用文献 RNA-activated protein cleavage with a CRISPR-associated endopeptidase. Science, 378, 2022

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