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2IJ0
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Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1
分子名称: Toxic shock syndrome toxin-1, penultimate affinity-matured variant of hVbeta 2.1, D10
著者Moza, B, Varma, A.K, Buonpane, R.A, Zhu, P, Herfst, C.A, Nicholson, M.J, Wilbuer, A.K, Nulifer, S, Wucherpfenning, K.W, McCormick, J.K, Kranz, D.M, Sundberg, E.J.
登録日2006-09-28
公開日2007-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1.
Embo J., 26, 2007
2J4W
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Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex
分子名称: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
著者Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2006-09-07
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
2ICF
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CRIg bound to C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
著者Wiesmann, C.
登録日2006-09-12
公開日2006-11-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2IPU
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PFA1 Fab fragment complexed with Abeta 1-8 peptide
分子名称: ACETAMIDE, GLYCEROL, IgG2a Fab fragment Heavy Chain, ...
著者Gardberg, A.S, Dealwis, C.
登録日2006-10-12
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
2J12
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Ad37 fibre head in complex with CAR D1
分子名称: CALCIUM ION, COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN
著者Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S.
登録日2006-08-08
公開日2006-08-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
2J5L
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Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex
分子名称: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
著者Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2006-09-18
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
2H2S
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Crystal Structure of E148A mutant of CLC-ec1 in SeCN-
分子名称: CLC Cl transporter, FAB fragment, heavy chain, ...
著者Nguitragool, W, Miller, C.
登録日2006-05-19
公開日2006-05-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006
2H8P
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Structure of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-07
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
2G2R
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Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
分子名称: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
著者Debler, E.W, Wilson, I.A.
登録日2006-02-16
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
2J8U
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Large CDR3a loop alteration as a function of MHC mutation.
分子名称: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, Beta-2-microglobulin, ...
著者Miller, P.J, Benhar, Y.P, Biddison, W, Collins, E.J.
登録日2006-10-27
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Single MHC mutation eliminates enthalpy associated with T cell receptor binding.
J. Mol. Biol., 373, 2007
2EXY
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Crystal structure of the E148Q Mutant of EcClC, Fab complexed in absence of bound ions
分子名称: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA
著者Lobet, S, Dutzler, R.
登録日2005-11-09
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006
2JIX
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Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor
分子名称: ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR
著者Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B.
登録日2007-07-02
公開日2007-07-10
最終更新日2020-03-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site.
Blood, 110, 2007
2G60
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Structure of anti-FLAG M2 Fab domain
分子名称: anti-FLAG M2 Fab heavy chain, anti-FLAG M2 Fab light chain
著者Roosild, T.P.
登録日2006-02-23
公開日2006-09-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.
Acta Crystallogr.,Sect.F, 62, 2006
2GK0
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Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2
分子名称: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain
著者Debler, E.W, Wilson, I.A.
登録日2006-03-31
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
2GSI
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Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
分子名称: Immunoglobulin (gamma) heavy chain (VH + CH1 fragment), Immunoglobulin (kappa) light chain, SODIUM ION, ...
著者Armstrong, A.A, Amzel, L.M.
登録日2006-04-26
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
To be Published
2H32
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Crystal structure of the pre-B cell receptor
分子名称: Immunoglobulin heavy chain, Immunoglobulin iota chain, Immunoglobulin omega chain, ...
著者Bankovich, A.J.
登録日2006-05-22
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Insight into Pre-B Cell Receptor Function
Science, 316, 2007
2HT2
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Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex
分子名称: BROMIDE ION, Fab fragment, heavy chain, ...
著者Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
登録日2006-07-25
公開日2006-09-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HLF
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Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex
分子名称: BROMIDE ION, Fab Fragment, Heavy chain, ...
著者Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
登録日2006-07-07
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
2HT3
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Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex
分子名称: BROMIDE ION, Fab fragment, Heavy chain, ...
著者Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
登録日2006-07-25
公開日2006-09-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
2FB4
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DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)
分子名称: IGG1-LAMBDA KOL FAB (HEAVY CHAIN), IGG1-LAMBDA KOL FAB (LIGHT CHAIN)
著者Marquart, M, Huber, R.
登録日1989-04-18
公開日1989-07-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The primary structure of crystallizable monoclonal immunoglobulin IgG1 Kol. II. Amino acid sequence of the L-chain, gamma-type, subgroup I
Biol.Chem.Hoppe-Seyler, 370, 1989
1MCD
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PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-D-PHE-B-ALA-L-HIS-D-PRO-NH2
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2020-03-04
実験手法X-RAY DIFFRACTION
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1N6Q
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HIV-1 Reverse Transcriptase Crosslinked to pre-translocation AZTMP-terminated DNA (complex N)
分子名称: 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*AP*(ATM))-3', 5'-D(*AP*T*GP*CP*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ...
著者Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, I, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E.
登録日2002-11-11
公開日2003-01-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of HIV-1 Reverse Transcriptase with Pre- and Post-translocation AZTMP-terminated DNA
Embo J., 21, 2002
1NAM
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MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BM3.3 T Cell Receptor alpha-Chain, BM3.3 T Cell Receptor beta-Chain, ...
著者Reiser, J.-B, Darnault, C, Gregoire, C, Mosser, T, Mazza, G, Kearnay, A, van der Merwe, P.A, Fontecilla-Camps, J.C, Housset, D, Malissen, B.
登録日2002-11-28
公開日2003-03-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献CDR3 loop flexibility contributes to the degeneracy of TCR recognition
Nat.Immunol., 4, 2003
1L7I
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Crystal Structure of the anti-ErbB2 Fab2C4
分子名称: SULFATE ION, chimera of Fab2C4: "humanized" murine monoclonal antibody
著者Vajdos, F.F, Adams, C.W, Breece, T.N, Presta, L.G, de Vos, A.M, Sidhu, S.S.
登録日2002-03-15
公開日2002-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
J.Mol.Biol., 320, 2002
1LO3
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Retro-Diels-Alderase Catalytic Antibody: Product Analogue
分子名称: 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID, If kappa light chain, Ig gamma 2a heavy chain
著者Hugot, M, Reymond, J.L, Baumann, U.
登録日2002-05-06
公開日2002-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.
Proc.Natl.Acad.Sci.USA, 99, 2002

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