7OM1
 
 | | Tankyrase 2 in complex with an inhibitor (OUL220) | | 分子名称: | 8-methoxy-4~{H}-thieno[2,3-c]isoquinolin-5-one, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-05-21 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Bioorg.Med.Chem., 52, 2021
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4DFR
 | | CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE | | 分子名称: | CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... | | 著者 | Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J. | | 登録日 | 1982-06-25 | | 公開日 | 1982-10-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
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7P49
 | | HLA-E*01:03 in complex with Mtb14 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Walters, L.C, Gillespie, G.M. | | 登録日 | 2021-07-10 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
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7OVX
 | | E3 RING ligase binding domain | | 分子名称: | E3 ubiquitin-protein ligase TRIM7, Peptide G | | 著者 | James, L.C. | | 登録日 | 2021-06-15 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | E3 ligase targeting domain
To Be Published
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7P0U
 | | ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide | | 分子名称: | 1,2-ETHANEDIOL, Activator of apoptosis harakiri, Apoptosis inhibitor, ... | | 著者 | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.99374259 Å) | | 主引用文献 | Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk.
Viruses, 13, 2021
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7OW2
 | | E3 RING ligase binding domain with peptide | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF187 peptide, E3 ubiquitin-protein ligase TRIM7, ... | | 著者 | James, L.C. | | 登録日 | 2021-06-16 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | E3 ligase targeting domain
To Be Published
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7P4B
 | | HLA-E*01:03 in complex with IL9 | | 分子名称: | Beta-2-microglobulin, ESAT-6-like protein EsxH, GLYCEROL, ... | | 著者 | Walters, L.C, Gillespie, G.M. | | 登録日 | 2021-07-10 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
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7Q2U
 | | The crystal structure of the HINT1 Q62A mutant. | | 分子名称: | CACODYLATE ION, HEXAETHYLENE GLYCOL, Histidine triad nucleotide-binding protein 1, ... | | 著者 | Dolot, R.M, Strom, A.M, Wagner, C.R. | | 登録日 | 2021-10-26 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides.
Biochemistry, 61, 2022
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7Q1E
 | | CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX | | 分子名称: | Centromere protein J, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Campanacci, V, Gigant, b. | | 登録日 | 2021-10-19 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7POX
 | | TNKS2 in complex with OM-1700, treated with H2O2 | | 分子名称: | N-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]pyridine-2-carboxamide, Poly [ADP-ribose] polymerase tankyrase-2 | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-09-10 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The zinc-binding motif in tankyrases is required for the structural integrity of the catalytic ADP-ribosyltransferase domain.
Open Biology, 12, 2022
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7Q4L
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7PFX
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7PEW
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7PFC
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7PEY
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7PEX
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7PEZ
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7PET
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7PF3
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7PF5
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7PF4
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7PFU
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7PF6
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7PEV
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7PF2
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