PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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4IAD	Low temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphorylated peptide pSP20, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-06 公開日 2013-06-12 最終更新日 2016-09-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
6T1P	ASR Alternansucrase in complex with isomaltononaose 分子名称: Alternansucrase, CALCIUM ION, alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose, ... 著者 Cioci, G, Molina, M, Moulis, C, Remaud-Simeon, M. 登録日 2019-10-04 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation. J.Biol.Chem., 295, 2020
6T95	Trypanothione Reductase from Leismania infantum in complex with 4a 分子名称: 1-[2-[5-[4-(4-azanylbutyl)-3-methyl-1,2,3-triazol-3-ium-1-yl]-2-[4-(2-phenylethyl)-1,3-thiazol-2-yl]phenoxy]ethyl]imidazolidin-2-one, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Carriles, A.A, Hermoso, J.A. 登録日 2019-10-25 公開日 2020-11-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity. Eur.J.Med.Chem., 244, 2022
6VWH	Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. 分子名称: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain 著者 Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. 登録日 2020-02-19 公開日 2020-05-13 最終更新日 2020-07-22 実験手法 ELECTRON MICROSCOPY (4.26 Å) 主引用文献 How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
6T9B	Crystal structrue of RSL W31A lectin mutant in complex with alpha-methylfucoside 分子名称: Fucose-binding lectin protein, GLYCINE, methyl alpha-L-fucopyranoside 著者 Houser, J, Komarek, J, Kozmon, S, Wimmerova, M. 登録日 2019-10-26 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 The CH-pi Interaction in Protein-Carbohydrate Binding: Bioinformatics and In Vitro Quantification. Chemistry, 26, 2020
6T6A	Crystal structure of DYRK1A complexed with KuFal319 (compound 11) 分子名称: 4-chloranyl-5~{H}-cyclohepta[b]indol-10-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, ... 著者 Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2019-10-18 公開日 2019-12-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 [ b ]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors. Molecules, 24, 2019
3JZS	Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ) 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, pDIQ peptide (12mer) 著者 Schonbrunn, E, Phan, J. 登録日 2009-09-24 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX. J.Biol.Chem., 285, 2010
6PYZ	Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PF-06840003 in Active Site 分子名称: (3S)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase, ... 著者 Pham, K.N, Lewis-Ballester, A, Yeh, S.R. 登録日 2019-07-31 公開日 2020-01-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase. J.Am.Chem.Soc., 141, 2019
2W4D	Acylphosphatase variant G91A from Pyrococcus horikoshii 分子名称: ACYLPHOSPHATASE, PHOSPHATE ION, POTASSIUM ION 著者 Lam, S.Y, Wong, K.B. 登録日 2008-11-25 公開日 2009-12-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity. Plos Biol., 9, 2011
3CL2	N1 Neuraminidase N294S + Oseltamivir 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase 著者 Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. 登録日 2008-03-18 公開日 2008-05-20 最終更新日 2018-08-22 実験手法 X-RAY DIFFRACTION (2.538 Å) 主引用文献 Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453, 2008
6TDF	Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 3 分子名称: 2-[[3,5-bis(chloranyl)-4-(4~{H}-1,2,4-triazol-3-yl)phenyl]-(2-hydroxyethyl)amino]ethanol, 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, ... 著者 Raimi, O.G, Stanley, M, Lockhart, D. 登録日 2019-11-08 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295, 2020
4IB0	X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-07 公開日 2013-12-11 最終更新日 2014-05-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
6PY3	Crystal structure of ligand-binding domain of Pseudomonas fluorescens chemoreceptor CtaA in complex with L-isoleucine 分子名称: ISOLEUCINE, Putative methyl-accepting chemotaxis protein 著者 Ud-Din, I.A, Khan, M.F, Roujeinikova, A. 登録日 2019-07-28 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Broad Specificity of Amino Acid Chemoreceptor CtaA ofPseudomonas fluorescensIs Afforded by Plasticity of Its Amphipathic Ligand-Binding Pocket. Mol.Plant Microbe Interact., 33, 2020
6THQ	Crystal structure of branched-chain aminotransferase from thermophilic archaea Thermoproteus uzoniensis with norvaline 分子名称: 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-PENTANOIC ACID, Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Boyko, K.M, Nikolaeva, A.Y, Bezsudnova, E.Y, Popov, V.O. 登録日 2019-11-21 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Three-Dimensional Structure of Branched-Chain Amino Acid Transaminase from Thermoproteus uzoniensis in Complex with L-Norvaline Crystallography Reports, 2020
4IAZ	Structure of cAMP dependent protein kinase A in complex with high Ba2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, BARIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-07 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
6T3V	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - malic acid 分子名称: (2S)-2-hydroxybutanedioic acid, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Rutkiewicz, M, Bujacz, A, Rum, J, Bujacz, G. 登録日 2019-10-11 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials, 14, 2021
3K7H	Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain 分子名称: Indian hedgehog protein, SULFATE ION, ZINC ION 著者 He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. 登録日 2009-10-13 公開日 2011-01-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain To be Published
6W6Z	BlsA ground state 分子名称: BLUF domain-containing protein, FLAVIN MONONUCLEOTIDE 著者 Chitrakar, I, French, J.B. 登録日 2020-03-18 公開日 2020-10-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA. Acs Infect Dis., 6, 2020
6T5E	Hydroxylamine Oxidoreductase from Brocadia fulgida 分子名称: HEME C, Hydroxylamine oxidoreductase-like protein, SULFATE ION 著者 Akram, M, Dietl, A, Mueller, M, Barends, T. 登録日 2019-10-16 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Purification of the key enzyme complexes of the anammox pathway from DEMON sludge. Biopolymers, 112, 2021
6Q8E	Crystal structure of branched-chain amino acid aminotransferase from Thermobaculum terrenum in PMP-form 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Branched-chain-amino-acid aminotransferase, CHLORIDE ION 著者 Boyko, K.M, Bezsudnova, E.Y, Nikolaeva, A.Y, Zeifman, Y.S, Rakitina, T.V, Popov, V.O. 登録日 2018-12-14 公開日 2019-01-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Biochemical and structural insights into PLP fold type IV transaminase from Thermobaculum terrenum. Biochimie, 158, 2018
6TGP	Cryo-EM structure of AtNBR1-PB1 filament (S-type) 分子名称: Protein NBR1 homolog 著者 Jakobi, A.J, Sachse, C. 登録日 2019-11-17 公開日 2020-02-19 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake. Nat Commun, 11, 2020
4IC2	Crystal structure of the XIAP RING domain 分子名称: E3 ubiquitin-protein ligase XIAP, NICKEL (II) ION, ZINC ION 著者 Linke, K, Nakatani, Y, Day, C.L. 登録日 2012-12-09 公開日 2012-12-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase Biochem.J., 450, 2013
4ICC	Crystal structure of human AKR1B10 complexed with NADP+ and JF0064 分子名称: 2,2',3,3',5,5',6,6'-octafluorobiphenyl-4,4'-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Porte, S, de Lera, A.R, Martin, M.J, de la Fuente, J.A, Klebe, G, Farres, J, Pares, X, Podjarny, A. 登録日 2012-12-10 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design. Acta Crystallogr.,Sect.D, 70, 2014
6TJY	Crystal structure of haemagglutinin from (A/seal/Germany/1/2014) seal H10N7 influenza virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. 登録日 2019-11-27 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
6QCX	Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer 分子名称: MAGNESIUM ION, PHOSPHATE ION, PYROPHOSPHATE 2-, ... 著者 Cusack, S, Drncova, P. 登録日 2018-12-31 公開日 2019-06-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structural snapshots of actively transcribing influenza polymerase. Nat.Struct.Mol.Biol., 26, 2019

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