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1NHU
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Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor
分子名称: (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE
著者Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G.
登録日2002-12-19
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition
J.Biol.Chem., 278, 2003
4ERT
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BU of 4ert by Molmil
Crystal structure of rabbit ryanodine receptor 1 (2734-2940)
分子名称: GLYCEROL, POTASSIUM ION, Ryanodine receptor 1
著者Yuchi, Z, Lau, K, Van Petegem, F.
登録日2012-04-20
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ESU
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Crystal structure of rabbit ryanodine receptor 1 mutant S2776M
分子名称: GLYCEROL, Ryanodine receptor 1
著者Yuchi, Z, Lau, K, Van Petegem, F.
登録日2012-04-23
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4M5S
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BU of 4m5s by Molmil
Human alphaB crystallin core domain in complex with C-terminal peptide
分子名称: Alpha-crystallin B chain, SUCCINIC ACID
著者Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
3N8V
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BU of 3n8v by Molmil
Crystal Structure of Unoccupied Cyclooxygenase-1
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Sidhu, R.S.
登録日2010-05-28
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Comparison of Cyclooxygenase-1 Crystal Structures: Cross-Talk between Monomers Comprising Cyclooxygenase-1 Homodimers
Biochemistry, 49, 2010
4JMR
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BU of 4jmr by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
分子名称: Env protein, Gag protein
著者Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
登録日2013-03-14
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
4DCF
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BU of 4dcf by Molmil
Structure of MTX-II from Bothrops brazili
分子名称: MTX-II chain A, TETRAETHYLENE GLYCOL
著者Ullah, A, Souza, T.A.C.B, Betzel, C, Murakami, M.T, Arni, R.K.
登録日2012-01-17
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic portrayal of different conformational states of a Lys49 phospholipase A2 homologue: insights into structural determinants for myotoxicity and dimeric configuration.
Int.J.Biol.Macromol., 51, 2012
4DI4
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BU of 4di4 by Molmil
Crystal structure of a 3:1 complex of Treponema pallidum TatP(T) (Tp0957) bound to TatT (Tp0956)
分子名称: TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, TatP(T) (Tp0957), ...
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2012-01-30
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.714 Å)
主引用文献Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT).
J.Mol.Biol., 420, 2012
4J8Z
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Crystal Structure of the Human SPOP BTB Domain
分子名称: Speckle-type POZ protein
著者Stead, M.A, Wright, S.C.
登録日2013-02-15
公開日2013-09-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP
Acta Crystallogr.,Sect.D, 69, 2013
6Q2P
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BU of 6q2p by Molmil
Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
登録日2019-08-08
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.452 Å)
主引用文献Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
4JH8
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Crystal Structure of FosB from Bacillus cereus with Zinc and L-Cysteine-Fosfomycin Ternary Complex
分子名称: CYSTEINE, FOSFOMYCIN, GLYCEROL, ...
著者Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
登録日2013-03-04
公開日2013-10-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
4NFE
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BU of 4nfe by Molmil
Human kallikrein-related peptidase 2 in complex with benzamidine
分子名称: BENZAMIDINE, Kallikrein-2, SULFATE ION
著者Skala, W, Brandstetter, H, Magdolen, V, Goettig, P.
登録日2013-10-31
公開日2014-10-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity
J.Biol.Chem., 289, 2014
4JWH
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BU of 4jwh by Molmil
Crystal structure of spTrm10(Full length)-SAH complex
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine(9)-N1)-methyltransferase
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
3QXT
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BU of 3qxt by Molmil
Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody in Complex with Methotrexate
分子名称: Anti-Methotrexate CDR1-3 Graft VHH, METHOTREXATE, SODIUM ION
著者Fanning, S.W, Horn, J.R.
登録日2011-03-02
公開日2011-07-06
最終更新日2013-09-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Protein Sci., 20, 2011
4JRT
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BU of 4jrt by Molmil
Crystal structure of an A-form RNA duplex containing three GU base pairs
分子名称: RNA (5'-R(P*CP*CP*UP*GP*CP*AP*CP*UP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*UP*GP*GP*UP*GP*CP*GP*GP*G)-3')
著者Kondo, J, Dock-Bregeon, A.C, Willkomm, D.K, Hartmann, R.K, Westhof, E.
登録日2013-03-21
公開日2013-06-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet
Acta Crystallogr.,Sect.F, 69, 2013
1O71
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Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with glycerol
分子名称: GLYCEROL, STICHOLYSIN II
著者Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A.
登録日2002-10-23
公開日2003-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
6Q2Q
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BU of 6q2q by Molmil
Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
著者Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
登録日2019-08-08
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
4DJ2
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BU of 4dj2 by Molmil
Unwinding the Differences of the Mammalian PERIOD Clock Proteins from Crystal Structure to Cellular Function
分子名称: Period circadian protein homolog 1
著者Kucera, N, Schmalen, I, Hennig, S, Oellinger, R, Strauss, H.M, Grudziecki, A, Wieczorek, C, Kramer, A, Wolf, E.
登録日2012-02-01
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function.
Proc.Natl.Acad.Sci.USA, 109, 2012
4JWJ
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BU of 4jwj by Molmil
Crystal structure of scTrm10(84)-SAH complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Yan, W, Shao, Z.
登録日2013-03-27
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
Nucleic Acids Res., 42, 2014
4JFN
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BU of 4jfn by Molmil
Crystal structure of the N-terminal, growth factor-like domain of the amyloid precursor protein bound to copper
分子名称: Amyloid beta A4 protein, COPPER (II) ION, GLYCEROL
著者Wild, K, Baumkotter, F, Kins, S.
登録日2013-02-28
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain
J.Neurosci., 34, 2014
8R1F
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BU of 8r1f by Molmil
Monomeric E6AP-E6-p53 ternary complex
分子名称: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ...
著者Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H.
登録日2023-11-01
公開日2023-12-06
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
8R1G
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BU of 8r1g by Molmil
Dimeric ternary structure of E6AP-E6-p53
分子名称: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ...
著者Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H.
登録日2023-11-01
公開日2023-12-06
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
4JH9
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Crystal Structure of FosB from Bacillus cereus with Maganese and Potential BSH-Fosfomycin Product
分子名称: (2R)-2-azanyl-3-[(1R,2S)-2-oxidanyl-1-phosphono-propyl]sulfanyl-propanoic acid, MANGANESE (II) ION, Metallothiol transferase FosB
著者Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
登録日2013-03-04
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
1O6E
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BU of 1o6e by Molmil
Epstein-Barr virus protease
分子名称: CAPSID PROTEIN P40, PHOSPHORYLISOPROPANE
著者Buisson, M, Hernandez, J, Lascoux, D, Schoehn, G, Forest, E, Arlaud, G, Seigneurin, J, Ruigrok, R.W.H, Burmeister, W.P.
登録日2002-09-13
公開日2002-11-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of the Epstein-Barr Virus Protease Shows Rearrangement of the Processed C Terminus
J.Mol.Biol., 324, 2002
2XPD
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BU of 2xpd by Molmil
Reduced Thiol peroxidase (Tpx) from yersinia Pseudotuberculosis
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, THIOL PEROXIDASE
著者Gabrielsen, M, Zetterstrom, C.E, Wang, D, Elofsson, M, Roe, A.J.
登録日2010-08-26
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterisation of Tpx from Yersinia Pseudotuberculosis Reveals Insights Into the Binding of Salicylidene Acylhydrazide Compounds.
Plos One, 7, 2012

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