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1VG3
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y/S77F mutant
分子名称: SULFATE ION, octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
7DBJ
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Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046
分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase B chain, ...
著者Sogabe, S, Miwa, M.
登録日2020-10-20
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Identification of the first highly selective inhibitor of human lactate dehydrogenase B.
Sci Rep, 11, 2021
7DBK
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Crystal structure of human LDHB in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase B chain
著者Sogabe, S, Miwa, M.
登録日2020-10-20
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Identification of the first highly selective inhibitor of human lactate dehydrogenase B.
Sci Rep, 11, 2021
4PF3
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Mineralocorticoid receptor ligand-binding domain with compuond 37a
分子名称: 1,2-ETHANEDIOL, 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor
著者Sogabe, S, Habuka, N.
登録日2014-04-28
公開日2014-11-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists
Bioorg.Med.Chem., 22, 2014
5HVW
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Monomeric IgG4 Fc
分子名称: GLYCEROL, Ig gamma-4 chain C region, ZINC ION, ...
著者Oganesyan, V.Y, Shan, L, Dall'Acqua, W.F.
登録日2016-01-28
公開日2016-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Generation and Characterization of an IgG4 Monomeric Fc Platform.
Plos One, 11, 2016
5I4A
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X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA
分子名称: Argonaute protein, RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*U)-3')
著者Doxzen, K.W, Kaya, E, Knoll, K.R, Wilson, R.C, Strutt, S.C, Kranzusch, P.J, Doudna, J.A.
登録日2016-02-11
公開日2016-03-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献A bacterial Argonaute with noncanonical guide RNA specificity.
Proc.Natl.Acad.Sci.USA, 113, 2016
3MJO
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Small subunit (R2F) of native ribonucleotide reductase from Corynebacterium ammoniagenes
分子名称: MANGANESE (III) ION, Ribonucleotide reductase subunit R2F
著者Ogata, H, Stolle, P, Stehr, M, Auling, G, Lubitz, W.
登録日2010-04-13
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献A Tyrosyl-Dimanganese Coupled Spin System is the Native Metalloradical Cofactor of the R2F Subunit of the Ribonucleotide Reductase of Corynebacterium ammoniagenes.
J.Am.Chem.Soc., 132, 2010
7DL5
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Crystal structure of Thermotoga Maritima ferritin mutant at 2.3 Angstrom resolution
分子名称: FE (III) ION, Ferritin, MAGNESIUM ION
著者Liu, Y, Leng, X, Zang, J, Zhao, G.
登録日2020-11-26
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A short helix regulates conversion of dimeric and 24-meric ferritin architectures.
Int.J.Biol.Macromol., 203, 2022
8BN3
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Yeast 80S, ES7s delta, eIF5A, Stm1 containing
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N.
登録日2022-11-12
公開日2024-01-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes.
Nucleic Acids Res., 52, 2024
5HWZ
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Crystal structure of nitrophorin 4 D30N mutant with nitrite
分子名称: NITRITE ION, Nitrophorin-4, PROTOPORPHYRIN IX CONTAINING FE
著者Ogata, H, He, C, Lubitz, W.
登録日2016-01-29
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Elucidation of the heme active site electronic structure affecting the unprecedented nitrite dismutase activity of the ferrihemebproteins, the nitrophorins.
Chem Sci, 7, 2016
6M7Y
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Dehydratase, NisB, bound to a non-eliminable substrate analog
分子名称: Lantibiotic, Nisin biosynthesis protein NisB
著者Cogan, D.P, Nair, S.K.
登録日2018-08-21
公開日2019-08-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116, 2019
3VHU
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BU of 3vhu by Molmil
Mineralocorticoid receptor ligand-binding domain with spironolactone
分子名称: Mineralocorticoid receptor, SPIRONOLACTONE
著者Sogabe, S, Habuka, N.
登録日2011-09-07
公開日2011-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists
J.Med.Chem., 54, 2011
8S1P
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YlmH bound to PtRNA-50S
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N.
登録日2024-02-15
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (1.96 Å)
主引用文献A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Nucleic Acids Res., 2024
7A99
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Crystal structure of the Phe57Trp mutant of the arginine-bound form of domain 1 from TmArgBP
分子名称: ACETATE ION, ARGININE, Amino acid ABC transporter, ...
著者Balasco, N, Vitagliano, L, Smaldone, G, Ruggiero, A.
登録日2020-09-01
公開日2020-11-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Development of a Protein Scaffold for Arginine Sensing Generated through the Dissection of the Arginine-Binding Protein from Thermotoga maritima .
Int J Mol Sci, 21, 2020
7DDI
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BU of 7ddi by Molmil
Crystal structures of Na+,K+-ATPase in complex with digitoxin
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C.
登録日2020-10-29
公開日2021-01-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.72 Å)
主引用文献Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
7DDK
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Crystal structures of Na+,K+-ATPase in complex with rostafuroxin
分子名称: (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C.
登録日2020-10-29
公開日2021-01-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
8S1U
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YlmH bound to stalled 50S subunits with RqcH and PtRNA
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Paternoga, H, Wilson, D.N.
登録日2024-02-16
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Nucleic Acids Res., 2024
1H1C
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BU of 1h1c by Molmil
Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima
分子名称: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Vega, M.C, Fernandez, F.J, Wilmanns, M.
登録日2002-07-08
公開日2004-03-19
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
2XON
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BU of 2xon by Molmil
Structure of TmCBM61 in complex with beta-1,4-galactotriose at 1.4 A resolution
分子名称: 1,2-ETHANEDIOL, ARABINOGALACTAN ENDO-1,4-BETA-GALACTOSIDASE, CALCIUM ION, ...
著者Cid, M, Lodberg-Pedersen, H, Kaneko, S, Coutinho, P.M, Henrissat, B, Willats, W.G.T, Boraston, A.B.
登録日2010-08-20
公開日2010-09-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Recognition of the Helical Structure of Beta-1,4-Galactan by a New Family of Carbohydrate-Binding Modules.
J.Biol.Chem., 285, 2010
1A0E
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BU of 1a0e by Molmil
XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA
分子名称: COBALT (II) ION, XYLOSE ISOMERASE
著者Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D.
登録日1997-11-28
公開日1998-06-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
5LGF
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Solution structure of the N-terminal domain of Ogataea polymorpha telomerase reverse transcriptase
分子名称: Telomerase reverse transcriptase
著者Polshakov, V.I, Mantsyzov, A.B, Efimov, S.V.
登録日2016-07-07
公開日2017-07-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
8TJF
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BU of 8tjf by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
分子名称: Fab Lambda light chain, IgG1 Fab heavy chain
著者Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C.
登録日2023-07-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
8TI4
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monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
分子名称: GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ...
著者Oganesyan, V.Y, van Dyk, N, Mazor, Y.
登録日2023-07-19
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
7UHY
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Human GATOR2 complex
分子名称: GATOR complex protein MIOS, GATOR complex protein WDR24, GATOR complex protein WDR59, ...
著者Rogala, K.B, Valenstein, M.L, Lalgudi, P.V.
登録日2022-03-27
公開日2022-07-20
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structure of the nutrient-sensing hub GATOR2.
Nature, 607, 2022
5UX0
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X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA
分子名称: Argonaute protein, DNA (5'-D(P*AP*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*CP*C)-3'), RNA (5'-R(*G*GP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*AP*U)-3')
著者Doxzen, K.W, Doudna, J.A.
登録日2017-02-21
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.197 Å)
主引用文献DNA recognition by an RNA-guided bacterial Argonaute.
PLoS ONE, 12, 2017

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件を2024-07-17に公開中

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