7DBK

Crystal structure of human LDHB in complex with NADH

Summary for 7DBK

• Entry DOI: 10.2210/pdb7dbk/pdb
• Descriptor: L-lactate dehydrogenase B chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: lactate dehydrogenase, inhibitor, complex, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 299735.25

Authors

Sogabe, S.,Miwa, M. (deposition date: 2020-10-20, release date: 2021-10-20, Last modification date: 2023-11-29)

• Primary citation: Shibata, S.,Sogabe, S.,Miwa, M.,Fujimoto, T.,Takakura, N.,Naotsuka, A.,Kitamura, S.,Kawamoto, T.,Soga, T.; Identification of the first highly selective inhibitor of human lactate dehydrogenase B.; Sci Rep, 11:21353-21353, 2021; PubMed: 34725423; DOI: 10.1038/s41598-021-00820-7

Experimental method

X-RAY DIFFRACTION (1.802 Å)