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3QFP
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Crystal structure of yeast Hsp70 (Bip/Kar2) ATPase domain
分子名称: 78 kDa glucose-regulated protein homolog, PHOSPHATE ION
著者Yan, M, Li, J.Z, Sha, B.D.
登録日2011-01-22
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
3O44
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BU of 3o44 by Molmil
Crystal Structure of the Vibrio cholerae Cytolysin (HlyA) Heptameric Pore
分子名称: Hemolysin
著者De, S, Olson, R.
登録日2010-07-26
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins.
Proc.Natl.Acad.Sci.USA, 108, 2011
4PFC
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Crystal structure of insulin degrading enzyme complexed with inhibitor
分子名称: Insulin-degrading enzyme, ZINC ION, methyl [(2S)-2-(5-{5-[4-({(2S)-2-[(3S)-3-amino-2-oxopiperidin-1-yl]-2-cyclohexylacetyl}amino)phenyl]pentyl}-2-fluorophenyl)-3-(quinolin-3-yl)propyl]carbamate
著者Wang, Y, Guo, S.
登録日2014-04-28
公開日2015-06-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
J.Biol.Chem., 290, 2015
4P9I
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Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3401 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4NXK
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Crystal structure of Abp-D197A, a catalytic mutant of a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus
分子名称: Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ...
著者Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G.
登録日2013-12-09
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
4PF9
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Crystal structure of insulin degrading enzyme complexed with inhibitor
分子名称: Insulin-degrading enzyme, ZINC ION, methyl [(2S)-2-[4-({5-[4-({(2S)-2-[(3S)-3-amino-2-oxopiperidin-1-yl]-2-cyclohexylacetyl}amino)phenyl]pentyl}oxy)phenyl]-3-(quinolin-3-yl)propyl]carbamate
著者Wang, Y, Guo, S.
登録日2014-04-28
公開日2015-06-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
J.Biol.Chem., 290, 2015
4P9J
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Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)
分子名称: Ryanodine receptor 1
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4M82
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The structure of E292S glycosynthase variant of exo-1,3-beta-glucanase from Candida albicans complexed with p-nitrophenyl-gentiobioside (product) at 1.6A resolution
分子名称: 1,2-ETHANEDIOL, 4-nitrophenyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside, EXO-1,3-BETA-GLUCANASE, ...
著者Nakatani, Y, Cutfield, S.M, Larsen, D.S, Cutfield, J.F.
登録日2013-08-12
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.592 Å)
主引用文献Major Change in Regiospecificity for the Exo-1,3-beta-glucanase from Candida albicans following Its Conversion to a Glycosynthase.
Biochemistry, 53, 2014
3QFU
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BU of 3qfu by Molmil
Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP
分子名称: 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Yan, M, Li, J.Z, Sha, B.D.
登録日2011-01-22
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
3RRX
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BU of 3rrx by Molmil
Crystal Structure of Q683A mutant of Exo-1,3/1,4-beta-glucanase (ExoP) from Pseudoalteromonas sp. BB1
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Exo-1,3/1,4-beta-glucanase, ...
著者Nakatani, Y, Cutfield, S.M, Cutfield, J.F.
登録日2011-05-01
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and activity of exo-1,3/1,4-beta-glucanase from marine bacterium Pseudoalteromonas sp. BB1 showing a novel C-terminal domain
Febs J., 279, 2012
4P9L
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BU of 4p9l by Molmil
Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) disease mutant A1107M
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4361 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
3QML
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BU of 3qml by Molmil
The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor
分子名称: 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ...
著者Yan, M, Li, J.Z, Sha, B.D.
登録日2011-02-04
公開日2011-06-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
4PF7
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BU of 4pf7 by Molmil
Crystal structure of insulin degrading enzyme complexed with inhibitor
分子名称: (2S)-2-amino-N-{(1S)-1-cyclohexyl-2-[(4-methylphenyl)amino]-2-oxoethyl}-4-(methylselanyl)butanamide, Insulin-degrading enzyme, ZINC ION
著者Wang, Y, Guo, S.
登録日2014-04-28
公開日2015-06-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
J.Biol.Chem., 290, 2015
3RQR
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BU of 3rqr by Molmil
Crystal structure of the RYR domain of the rabbit ryanodine receptor
分子名称: (UNK)(UNK)(UNK)(UNK), Ryanodine receptor 1
著者Nair, U.B, Li, W, Dong, A, Walker, J.R, Gramolini, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2011-04-28
公開日2011-06-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural determination of the phosphorylation domain of the ryanodine receptor.
Febs J., 279, 2012
4NX0
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BU of 4nx0 by Molmil
Crystal structure of Abp-WT, a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus
分子名称: Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ...
著者Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G.
登録日2013-12-08
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
4NKK
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BU of 4nkk by Molmil
Crystal structure of a multi-drug resistant clinical isolate-769 HIV-1 protease variant that is resistant to the dimerization inhibitory activity of TLF-PafF
分子名称: HIV-1 protease
著者Yedidi, R.S, Proteasa, G, Kovari, L.C.
登録日2013-11-12
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A multi-drug resistant HIV-1 protease is resistant to the dimerization inhibitory activity of TLF-PafF.
J.Mol.Graph.Model., 53C, 2014
4PXI
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BU of 4pxi by Molmil
Elucidation of the Structural and Functional Mechanism of Action of the TetR Family Protein, CprB from S. coelicolor A3(2)
分子名称: CprB, DNA (5'-D(*AP*CP*AP*TP*AP*CP*GP*GP*GP*AP*CP*GP*CP*CP*CP*CP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(*AP*TP*AP*AP*AP*CP*GP*GP*GP*GP*CP*GP*TP*CP*CP*CP*GP*TP*AP*TP*GP*T)-3')
著者Hussain, B, Ruchika, B, Aruna, B, Ruchi, A.
登録日2014-03-24
公開日2014-07-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and functional basis of transcriptional regulation by TetR family protein CprB from S. coelicolor A3(2)
Nucleic Acids Res., 42, 2014
7W6Z
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BU of 7w6z by Molmil
Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P21
分子名称: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ZINC ION, Zinc metalloprotease
著者Imaizumi, Y, Takanuki, K, Nogi, T.
登録日2021-12-02
公開日2022-09-07
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
7W71
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Crystal structure of the PDZ-C domain of E. coli RseP in complex with 12C7 Fab
分子名称: Heavy chain of Fab, Light chain of Fab, Regulator of sigma-E protease RseP
著者Hirose, T, Katagiri, S, Nogi, T.
登録日2021-12-02
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
7W70
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BU of 7w70 by Molmil
Crystal structure of the PDZ-C domain fragment of Kangiella koreensis RseP orthologue
分子名称: Zinc metalloprotease
著者Miyoshi, K, Nogi, T.
登録日2021-12-02
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
7W6X
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BU of 7w6x by Molmil
Crystal structure of E. coli RseP in complex with batimastat
分子名称: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Regulator of sigma-E protease RseP, ZINC ION
著者Takanuki, K, Imaizumi, Y, Nogi, T.
登録日2021-12-02
公開日2022-09-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
7W6Y
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BU of 7w6y by Molmil
Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1
分子名称: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Anti sigma-E protein, RseA, ...
著者Imaizumi, Y, Takanuki, K, Nogi, T.
登録日2021-12-02
公開日2022-09-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
6GIL
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BU of 6gil by Molmil
NMR structure of temporin B in SDS micelles
分子名称: Temporin-B
著者Manzo, G, Mason, J.A.
登録日2018-05-12
公開日2018-06-13
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity.
Sci Rep, 9, 2019
6GIJ
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BU of 6gij by Molmil
NMR structure of temporin B KKG6A in SDS micelles
分子名称: temporinB_KKG6A
著者Manzo, G, Mason, J.A.
登録日2018-05-12
公開日2018-06-13
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity.
Sci Rep, 9, 2019
6IVM
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BU of 6ivm by Molmil
Crystal structure of a membrane protein P143A
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ...
著者Kittredge, A, Fukuda, F, Zhang, Y, Yang, T.
登録日2018-12-04
公開日2019-11-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019

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件を2024-09-11に公開中

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