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3CVJ
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BU of 3cvj by Molmil
Crystal structure of a putative phosphoheptose isomerase (bh3325) from bacillus halodurans c-125 at 2.00 A resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MAGNESIUM ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-04-18
公開日2008-05-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of putative phosphoheptose isomerase (NP_244191.1) from Bacillus halodurans at 2.00 A resolution
To be published
1A5R
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BU of 1a5r by Molmil
STRUCTURE DETERMINATION OF THE SMALL UBIQUITIN-RELATED MODIFIER SUMO-1, NMR, 10 STRUCTURES
分子名称: SUMO-1
著者Bayer, P, Arndt, A, Metzger, S, Mahajan, R, Melchior, F, Jaenicke, R, Becker, J.
登録日1998-02-18
公開日1998-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure determination of the small ubiquitin-related modifier SUMO-1.
J.Mol.Biol., 280, 1998
1GQI
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BU of 1gqi by Molmil
Structure of Pseudomonas cellulosa alpha-D-glucuronidase
分子名称: 1,2-ETHANEDIOL, ALPHA-GLUCURONIDASE, COBALT (II) ION, ...
著者Nurizzo, D, Nagy, T, Gilbert, H.J, Davies, G.J.
登録日2001-11-26
公開日2002-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献The Structural Basis for Catalysis and Specificity of the Pseudomonas Cellulosa Alpha-Glucuronidase, Glca67A
Structure, 10, 2002
5EZV
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BU of 5ezv by Molmil
X-ray crystal structure of AMP-activated protein kinase alpha-2/alpha-1 RIM chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) beta-1 gamma-1) co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid)
分子名称: 3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-2/alpha-1 RIM SWAP chimera, 5'-AMP-activated protein kinase subunit beta-1, ...
著者Langendorf, C.G, Kemp, B.E.
登録日2015-11-26
公開日2016-03-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding.
Nat Commun, 7, 2016
4BSP
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BU of 4bsp by Molmil
Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak
分子名称: HOLMIUM ATOM, R-SPONDIN-1, SULFATE ION
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
1H4U
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BU of 1h4u by Molmil
Domain G2 of mouse nidogen-1
分子名称: NIDOGEN-1
著者Hopf, M, Gohring, W, Ries, A, Timpl, R, Hohenester, E.
登録日2001-05-14
公開日2001-06-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1
Nat.Struct.Biol., 8, 2001
1A8K
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BU of 1a8k by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES
分子名称: HIV PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Weber, I.T, Wu, J, Adomat, J, Harrison, R.W, Kimmel, A.R, Wondrak, E.M, Louis, J.M.
登録日1998-03-27
公開日1999-01-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic analysis of human immunodeficiency virus 1 protease with an analog of the conserved CA-p2 substrate -- interactions with frequently occurring glutamic acid residue at P2' position of substrates.
Eur.J.Biochem., 249, 1997
4BZQ
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BU of 4bzq by Molmil
Structure of the Mycobacterium tuberculosis APS kinase CysC in complex with ADP and APS
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, ...
著者Poyraz, O, Schnell, R, Schneider, G.
登録日2013-07-29
公開日2014-08-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of the Kinase Domain of the Sulfate-Activating Complex in Mycobacterium Tuberculosis.
Plos One, 10, 2015
4F57
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BU of 4f57 by Molmil
Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient
分子名称: GLYCEROL, Heavy chain of Fab of a neutralizing antibody L1, Light chain of Fab of a neutralizing antibody L1
著者Pan, R.M, Kong, X.P.
登録日2012-05-12
公開日2013-03-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Plos Pathog., 9, 2013
5UFU
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BU of 5ufu by Molmil
Structure of AMPK bound to activator
分子名称: 1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ...
著者Calabrese, M.F, Kurumbail, R.G.
登録日2017-01-05
公開日2017-05-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.
Cell Metab., 25, 2017
2YL2
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BU of 2yl2 by Molmil
Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain
分子名称: ACETYL-COA CARBOXYLASE 1
著者Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U.
登録日2011-05-31
公開日2011-06-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
4JY5
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BU of 4jy5 by Molmil
Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, PGT122 heavy chain, PGT122 light chain
著者Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
登録日2013-03-29
公開日2013-05-08
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
6BL3
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BU of 6bl3 by Molmil
Crystal Complex of Cyclooxygenase-2 with indomethacin-butyldiamine-dansyl conjugate
分子名称: 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)butyl]acetamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xu, S, Uddin, M.J, Banerjee, S, Marnett, L.J.
登録日2017-11-09
公開日2018-11-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.217 Å)
主引用文献Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site.
J.Biol.Chem., 294, 2019
2ON5
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BU of 2on5 by Molmil
Structure of NaGST-2
分子名称: 1,2-ETHANEDIOL, GLUTATHIONE, Na Glutathione S-transferase 2
著者Asojo, O.A, Ngamelue, M, Homma, H, Goud, G, Zhan, B, Hotez, P.J.
登録日2007-01-23
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
Bmc Struct.Biol., 7, 2007
1LFI
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BU of 1lfi by Molmil
METAL SUBSTITUTION IN TRANSFERRINS: THE CRYSTAL STRUCTURE OF HUMAN COPPER-LACTOFERRIN AT 2.1 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ...
著者Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N.
登録日1992-02-10
公開日1993-10-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Metal substitution in transferrins: the crystal structure of human copper-lactoferrin at 2.1-A resolution.
Biochemistry, 31, 1992
4KNK
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BU of 4knk by Molmil
Crystal structure of Staphylococcus aureus hydrolase AmiA
分子名称: 1,2-ETHANEDIOL, Bifunctional autolysin, DI(HYDROXYETHYL)ETHER, ...
著者Buettner, F.M, Zoll, S, Stehle, T.
登録日2013-05-10
公開日2014-03-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.124 Å)
主引用文献Structure-function analysis of Staphylococcus aureus amidase reveals the determinants of peptidoglycan recognition and cleavage.
J.Biol.Chem., 289, 2014
5AFP
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BU of 5afp by Molmil
Neuronal calcium sensor-1 (NCS-1)from Rattus norvegicus complex with rhodopsin kinase peptide from Homo sapiens
分子名称: CALCIUM ION, NEURONAL CALCIUM SENSOR 1, RHODOPSIN KINASE, ...
著者Saleem, M, Karuppiah, V, Pandalaneni, S, Burgoyne, R, Derrick, J.P, Lian, L.Y.
登録日2015-01-23
公開日2015-03-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-Protein Coupled Receptor Kinase 1 (Grk1) Peptides Using Different Modes of Interactions.
J.Biol.Chem., 290, 2015
7JVV
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BU of 7jvv by Molmil
Crystal structure of human histone deacetylase 8 (HDAC8) E66D/Y306F double mutation complexed with a tetrapeptide substrate
分子名称: 1,2-ETHANEDIOL, ACE-ARG-HIS-ALY-ALY-MCM, GLYCEROL, ...
著者Osko, J.D, Christianson, D.W, Decroos, C, Porter, N.J, Lee, M.
登録日2020-08-24
公開日2020-12-16
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders.
J.Struct.Biol., 213, 2020
7XNS
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SARS-CoV-2 Omicron BA.2.12.1 variant spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wang, X, Wang, L.
登録日2022-04-29
公開日2022-07-13
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.
Nature, 608, 2022
2W5N
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BU of 2w5n by Molmil
Native structure of the GH93 alpha-L-arabinofuranosidase of Fusarium graminearum
分子名称: 1,2-ETHANEDIOL, ALPHA-L-ARABINOFURANOSIDASE, GLYCEROL, ...
著者Carapito, R, Imberty, A, Jeltsch, J.M, Byrns, S.C, Tam, P.H, Lowary, T.L, Varrot, A, Phalip, V.
登録日2008-12-11
公開日2009-03-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Basis of Arabinobio-Hydrolase Activity in Phytopathogenic Fungi. Crystal Structure and Catalytic Mechanism of Fusarium Graminearum Gh93 Exo-Alpha-L-Arabinanase.
J.Biol.Chem., 284, 2009
4MOT
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BU of 4mot by Molmil
Structure of Streptococcus pneumonia pare in complex with AZ13072886
分子名称: 1-[4-(3-methylbutyl)-5-oxo-6-(pyridin-3-yl)-4,5-dihydro[1,3]thiazolo[5,4-b]pyridin-2-yl]-3-prop-2-en-1-ylurea, Topoisomerase IV subunit B
著者Ogg, D, Boriack-Sjodin, P.A.
登録日2013-09-12
公開日2013-11-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Thiazolopyridone ureas as DNA gyrase B inhibitors: Optimization of antitubercular activity and efficacy.
Bioorg.Med.Chem.Lett., 24, 2014
2VTW
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BU of 2vtw by Molmil
Structure of the C-terminal head domain of the fowl adenovirus type 1 short fibre
分子名称: FIBER PROTEIN 2, GLYCEROL, SULFATE ION
著者ElBakkouri, M, Seiradake, E, Cusack, S, Ruigrok, R.W.H, Schoehn, G.
登録日2008-05-16
公開日2008-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the C-Terminal Head Domain of the Fowl Adenovirus Type 1 Short Fibre.
Virology, 378, 2008
7XIW
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BU of 7xiw by Molmil
SARS-CoV-2 Omicron BA.2 variant spike (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wang, X, Wang, L.
登録日2022-04-14
公開日2022-07-13
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.
Nature, 608, 2022
3JBT
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BU of 3jbt by Molmil
Atomic structure of the Apaf-1 apoptosome
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ...
著者Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y.
登録日2015-10-15
公開日2015-11-18
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
4BUO
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BU of 4buo by Molmil
High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
分子名称: GLYCINE, NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
著者Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A.
登録日2013-06-21
公開日2014-01-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014

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