4JFY
| Apo structure of phosphotyrosine (pYAb) scaffold | 分子名称: | Fab heavy chain, Fab light chain, TETRAETHYLENE GLYCOL | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | 登録日 | 2013-02-28 | 公開日 | 2013-08-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds. Nat.Biotechnol., 31, 2013
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3G8V
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3QCU
| Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ... | 著者 | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | 登録日 | 2011-01-17 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | 主引用文献 | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408, 2011
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4PO7
| Structure of the Sortilin:neurotensin complex at excess neurotensin concentration | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotensin/neuromedin N, Sortilin, ... | 著者 | Quistgaard, E.M, Groftehauge, M.K, Thirup, S.S. | 登録日 | 2014-02-25 | 公開日 | 2014-07-23 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci., 23, 2014
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4JLX
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4JQS
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4ESV
| A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ... | 著者 | Itsathitphaisarn, O, Wing, R.A, Eliason, W.K, Wang, J, Steitz, T.A. | 登録日 | 2012-04-23 | 公開日 | 2012-10-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation. Cell(Cambridge,Mass.), 151, 2012
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5OM3
| Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline | 分子名称: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER | 著者 | Schmidt, K, Muller, Y.A. | 登録日 | 2017-07-28 | 公開日 | 2018-05-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4PY0
| Crystal structure of P2Y12 receptor in complex with 2MeSATP | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), P2Y purinoceptor 12, ... | 著者 | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | 登録日 | 2014-03-25 | 公開日 | 2014-04-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
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2JSL
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures | 分子名称: | HUMAN TELOMERE DNA | 著者 | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | 登録日 | 2007-07-08 | 公開日 | 2008-07-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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4IQN
| Crystal structure of uncharacterized protein from Salmonella enterica subsp. enterica serovar typhimurium str. 14028s | 分子名称: | DI(HYDROXYETHYL)ETHER, Putative cytoplasmic protein, TETRAETHYLENE GLYCOL | 著者 | Chang, C, Hatzos-Skintges, C, Adkins, J.N, Brown, R.N, Cort, J.R, Heffron, F, Nakayasu, E.S, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) | 登録日 | 2013-01-11 | 公開日 | 2013-01-23 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of uncharacterized protein from salmonella enterica subsp. enterica serovar typhimurium str. 14028s To be Published
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3PUW
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4J0I
| Tannin acyl hydrolase in complex with 3,4-dihydroxybenzoate | 分子名称: | 3,4-DIHYDROXYBENZOIC ACID, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | 著者 | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | 登録日 | 2013-01-30 | 公開日 | 2013-05-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum. J.Mol.Biol., 425, 2013
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3RLK
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3H41
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4QJ4
| Structure of a fragment of human phospholipase C-beta3 delta472-569, bound to IP3 and in complex with Galphaq | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Lyon, A.M, Tesmer, J.J.G. | 登録日 | 2014-06-03 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular mechanisms of phospholipase C beta 3 autoinhibition. Structure, 22, 2014
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3GWR
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3Q4T
| Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dorsomorphin | 分子名称: | 1,2-ETHANEDIOL, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, Activin receptor type-2A, ... | 著者 | Chaikuad, A, Alfano, I, Mahajan, P, Cooper, C.D.O, Sanvitale, C, Vollmar, M, Krojer, T, Muniz, J.R.C, Raynor, J, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-12-24 | 公開日 | 2011-02-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation. J.Biol.Chem., 290, 2015
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2JSM
| MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural | 分子名称: | HUMAN TELOMERE DNA | 著者 | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | 登録日 | 2007-07-09 | 公開日 | 2008-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution Nucleic Acids Res., 35, 2007
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2JSK
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, 16 G Form 1, NMR, 10 Structures | 分子名称: | HUMAN TELOMERE DNA | 著者 | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | 登録日 | 2007-07-07 | 公開日 | 2008-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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4C6Y
| Ancestral PNCA (last common ancestors of Gram-positive and Gram- negative bacteria) beta-lactamase class A | 分子名称: | ACETATE ION, BETA-LACTAMASE, CHLORIDE ION, ... | 著者 | Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M. | 登録日 | 2013-09-19 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Phenotypic Comparisons of Consensus Variants Versus Laboratory Resurrections of Precambrian Proteins. Proteins, 82, 2014
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4ITZ
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4TQX
| Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone. | 分子名称: | ACETIC ACID, SULFATE ION, Sortase, ... | 著者 | Wallock-Richards, D.J, Marles-Wright, J, Clarke, D.J, Maitra, A, Dodds, M, Hanley, B, Campopiano, D.J. | 登録日 | 2014-06-12 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone. Chem.Commun.(Camb.), 51, 2015
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3GP3
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3H3R
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