4TQX
Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone.
Summary for 4TQX
Entry DOI | 10.2210/pdb4tqx/pdb |
Descriptor | Sortase, TETRAETHYLENE GLYCOL, ACETIC ACID, ... (5 entities in total) |
Functional Keywords | sortase, inhibitor, gram positive, cell wall, hydrolase |
Biological source | Streptococcus mutans |
Total number of polymer chains | 1 |
Total formula weight | 23094.12 |
Authors | Wallock-Richards, D.J.,Marles-Wright, J.,Clarke, D.J.,Maitra, A.,Dodds, M.,Hanley, B.,Campopiano, D.J. (deposition date: 2014-06-12, release date: 2015-05-20, Last modification date: 2023-12-20) |
Primary citation | Wallock-Richards, D.J.,Marles-Wright, J.,Clarke, D.J.,Maitra, A.,Dodds, M.,Hanley, B.,Campopiano, D.J. Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone. Chem.Commun.(Camb.), 51:10483-10485, 2015 Cited by PubMed: 26029850DOI: 10.1039/c5cc01816a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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