4TQX
Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sortase | polymer | 206 | 22743.8 | 1 | UniProt (Q8CM62) Pfam (PF04203) | Streptococcus mutans | |
| 2 | B (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 3 | C (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A: 41 - 246 (UniProt: Q8CM62)
| PDB | External Database | Details |
|---|---|---|
| Ala 139 | His 139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22743.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 350.3 | |
| All* | Total formula weight | 23094.1 |
