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7YSN
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BU of 7ysn by Molmil
Tubulin heterodimer structure of GMPCPP state in solution
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Tubulin alpha-1B chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
6LKR
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BU of 6lkr by Molmil
Crystal structure of mouse DCAR2 CRD domain complex
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-type lectin domain family 4, member b1, ...
著者Omahdi, Z, Horikawa, Y, Toyonaga, K, Kakuta, Y, Yamasaki, S.
登録日2019-12-20
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
4GOP
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BU of 4gop by Molmil
Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA
分子名称: DNA (25-MER), Putative uncharacterized protein, ZINC ION
著者Pavletich, N.P, Jie, F.
登録日2012-08-20
公開日2012-11-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and conformational change of a replication protein A heterotrimer bound to ssDNA.
Genes Dev., 26, 2012
2GE7
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BU of 2ge7 by Molmil
Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein
分子名称: Nucleocapsid protein
著者Jayaram, H, Fan, H, Bowman, B.R, Ooi, A, Jayaram, J, Collisson, E.W, Lescar, J, Prasad, B.V.
登録日2006-03-18
公開日2006-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structures of the N- and C-terminal domains of a coronavirus nucleocapsid protein: implications for nucleocapsid formation.
J.Virol., 80, 2006
7YSQ
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BU of 7ysq by Molmil
GTPgammaS Tube decorated with kinesin
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
2GAH
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BU of 2gah by Molmil
Heterotetrameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution
分子名称: 2-FUROIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, Z.W, Hassan-Abdulah, A, Zhao, G, Jorns, M.S, Mathews, F.S.
登録日2006-03-08
公開日2006-08-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 a resolution.
J.Mol.Biol., 360, 2006
7YSO
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BU of 7yso by Molmil
Tubulin heterodimer structure of GDP-1 state in solution
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha-1B chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
7YSR
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BU of 7ysr by Molmil
GTPgammaS MT decorated with kinesin
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
4HXG
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BU of 4hxg by Molmil
Pyrococcus horikoshii acylaminoacyl peptidase (orthorhombic crystal form)
分子名称: CHLORIDE ION, HEXANE-1,6-DIOL, MAGNESIUM ION, ...
著者Kiss-Szeman, A, Menyhard, D.K, Tichy-Racs, E, Hornung, B, Radi, K, Szeltner, Z, Domokos, K, Szamosi, I, Naray-Szabo, G, Polgar, L, Harmat, V.
登録日2012-11-09
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
2GHV
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BU of 2ghv by Molmil
Crystal structure of SARS spike protein receptor binding domain
分子名称: Spike glycoprotein
著者Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C.
登録日2006-03-27
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
J.Biol.Chem., 281, 2006
6LW3
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BU of 6lw3 by Molmil
Crystal structure of RuvC from Pseudomonas aeruginosa
分子名称: Crossover junction endodeoxyribonuclease RuvC
著者Hu, Y, He, Y, Lin, Z.
登録日2020-02-07
公開日2020-02-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Biochemical and structural characterization of the Holliday junction resolvase RuvC from Pseudomonas aeruginosa.
Biochem.Biophys.Res.Commun., 525, 2020
6M94
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BU of 6m94 by Molmil
Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex
分子名称: Catenin beta-1, DIMETHYL SULFOXIDE, F-box/WD repeat-containing protein 1A, ...
著者Simonetta, K.R, Clifton, M.C, Walter, R.L, Ranieri, G.M, Carter, J.J.
登録日2018-08-22
公開日2019-04-03
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
Nat Commun, 10, 2019
4LI2
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BU of 4li2 by Molmil
Crystal Structures of Lgr4 and its complex with R-spondin1
分子名称: Leucine-rich repeat-containing G-protein coupled receptor 4, R-spondin-1
著者Xu, Y, Rajashankar, K, Robev, D.
登録日2013-07-02
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structures of lgr4 and its complex with R-spondin1.
Structure, 21, 2013
2GCA
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BU of 2gca by Molmil
apo form of L. casei FPGS
分子名称: Folylpolyglutamate synthase
著者Smith, C.A, Cross, J.A, Bognar, A.L, Sun, X.
登録日2006-03-13
公開日2006-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.
Acta Crystallogr.,Sect.D, 62, 2006
6LPP
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BU of 6lpp by Molmil
Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate (D-2-HG)
分子名称: (2R)-2-hydroxypentanedioic acid, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ...
著者Yang, J, Zhu, H, Ding, J.
登録日2020-01-12
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
2GD7
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BU of 2gd7 by Molmil
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
分子名称: HEXIM1 protein
著者Dames, S.A.
登録日2006-03-15
公開日2007-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6MBB
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BU of 6mbb by Molmil
Human Bfl-1 in complex with the designed peptide dF1
分子名称: Bcl-2-related protein A1, dF1
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
7YNF
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BU of 7ynf by Molmil
CCA-bound alpha-synuclein fibrils
分子名称: Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-30
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献CCA-bound alpha-synuclein fibrils
To Be Published
2GGZ
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BU of 2ggz by Molmil
Crystal Structure of Human Guanylate Cyclase Activating Protein-3
分子名称: CALCIUM ION, Guanylyl cyclase-activating protein 3
著者Stephen, R.
登録日2006-03-24
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies.
J.Mol.Biol., 359, 2006
2GHT
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BU of 2ght by Molmil
CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
著者Zhang, Y, Noel, J.P.
登録日2006-03-27
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
7YQ8
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BU of 7yq8 by Molmil
Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ...
著者Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S.
登録日2022-08-05
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Nat Commun, 14, 2023
4GPL
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BU of 4gpl by Molmil
Structure of Cbl(TKB) bound to a phosphorylated pentapeptide
分子名称: ACE-PTR-THR-PRO-GLU-PRO, PEPTIDE INHIBITOR, E3 ubiquitin-protein ligase CBL
著者Borgstahl, G, Natarajan, A.
登録日2012-08-21
公開日2013-09-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides.
Sci Rep, 3, 2013
2GAR
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BU of 2gar by Molmil
A PH-DEPENDENT STABLIZATION OF AN ACTIVE SITE LOOP OBSERVED FROM LOW AND HIGH PH CRYSTAL STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
分子名称: GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION
著者Su, Y, Yamashita, M.M, Greasley, S.E, Mullen, C.A, Shim, J.H, Jennings, P.A, Benkovic, S.J, Wilson, I.A.
登録日1998-05-13
公開日1998-08-12
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.
J.Mol.Biol., 281, 1998
6LVC
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BU of 6lvc by Molmil
Structure of Dimethylformamidase, dimer
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R.
登録日2020-02-02
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
5IJO
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BU of 5ijo by Molmil
Alternative composite structure of the inner ring of the human nuclear pore complex (16 copies of Nup188, 16 copies of Nup205)
分子名称: Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ...
著者Kosinski, J, Mosalaganti, S, von Appen, A, Beck, M.
登録日2016-03-02
公開日2016-04-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (21.4 Å)
主引用文献Molecular architecture of the inner ring scaffold of the human nuclear pore complex.
Science, 352, 2016

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