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7D8B
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BU of 7d8b by Molmil
Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways
分子名称: Eukaryotic translation initiation factor 4E, VH-S4
著者Frosi, Y, Lin, Y.C, Jiang, S, Brown, C.J.
登録日2020-10-07
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex.
Nat Commun, 13, 2022
6LLZ
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BU of 6llz by Molmil
Crystal Structure of Fagopyrum esculentum M UGT708C1 complexed with UDP-glucose
分子名称: UDP-glycosyltransferase 708C1, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Wang, X, Liu, M.
登録日2019-12-24
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Crystal Structures of theC-Glycosyltransferase UGT708C1 from Buckwheat Provide Insights into the Mechanism ofC-Glycosylation.
Plant Cell, 32, 2020
2GH2
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BU of 2gh2 by Molmil
1.5 A Resolution R. Norvegicus Cysteine Dioxygenase Structure Crystallized in the Presence of Cysteine
分子名称: Cysteine dioxygenase type I, FE (III) ION, SULFATE ION
著者Simmons, C.R, Karplus, P.A, Stipanuk, M.H.
登録日2006-03-24
公開日2006-04-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION.
J.Biol.Chem., 281, 2006
6LMY
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BU of 6lmy by Molmil
Crystal structure of DUSP22 mutant_C88S/S93A
分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION
著者Lai, C.H, Lyu, P.C.
登録日2019-12-27
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
6OQP
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BU of 6oqp by Molmil
U-AITx-Ate1
分子名称: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE
著者Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
登録日2019-04-28
公開日2019-07-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
2GHW
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BU of 2ghw by Molmil
Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R
分子名称: CHLORIDE ION, Spike glycoprotein, anti-sars scFv antibody, ...
著者Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C.
登録日2006-03-27
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
J.Biol.Chem., 281, 2006
7Z1X
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BU of 7z1x by Molmil
Crystal structure of human Gasdermin D complexed with nanobodies VHH-2 and VHH-6
分子名称: Gasdermin-D, VHH-2, VHH-6
著者Kopp, A, Hagelueken, G, Geyer, M.
登録日2022-02-25
公開日2023-09-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Pyroptosis inhibiting nanobodies block Gasdermin D pore formation.
Nat Commun, 14, 2023
7YTO
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BU of 7yto by Molmil
The Crystal Structure Analysis of Creatine Amidinohydrolase from Alcaligenes sp. KS-85
分子名称: Creatine amidinohydrolase
著者Chen, R.S.
登録日2022-08-15
公開日2023-08-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Creatinase: Using Increased Entropy to Improve the Activity and Thermostability.
J.Phys.Chem.B, 127, 2023
6LOT
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BU of 6lot by Molmil
Crystal structure of DUSP22 mutant_N128D
分子名称: Dual specificity protein phosphatase 22, SULFATE ION
著者Lai, C.H, Lyu, P.C.
登録日2020-01-07
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
2G8G
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BU of 2g8g by Molmil
Structurally mapping the diverse phenotype of Adeno-Associated Virus serotype 4
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid
著者Govindasamy, L, Padron, E, McKenna, R, Muzyczka, N, Chiorini, J.A, Agbandje-McKenna, M.
登録日2006-03-02
公開日2007-01-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
J.Virol., 80, 2006
6LZG
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BU of 6lzg by Molmil
Structure of novel coronavirus spike receptor-binding domain complexed with its receptor ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
著者Wang, Q.H, Song, H, Qi, J.X.
登録日2020-02-19
公開日2020-03-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2.
Cell, 181, 2020
2GFP
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BU of 2gfp by Molmil
Structure of the Multidrug Transporter EmrD from Escherichia coli
分子名称: Multidrug resistance protein D
著者Yin, Y, He, X, Szewczyk, P, Nguyen, T, Chang, G.
登録日2006-03-22
公開日2006-05-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the multidrug transporter EmrD from Escherichia coli
Science, 312, 2006
6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
登録日2020-01-26
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
4GGK
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BU of 4ggk by Molmil
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate
分子名称: Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION
著者Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L.
登録日2012-08-06
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
7ZG3
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BU of 7zg3 by Molmil
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228
分子名称: N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-[(1~{S})-1,2,2-trimethylcyclopropyl]pyrrolo[1,2-c]pyrimidine-3-carboxamide
著者Davies, J.R, Scaletti, E, Stenmark, P.
登録日2022-04-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228
To Be Published
7YW9
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BU of 7yw9 by Molmil
Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG
分子名称: ACETATE ION, CmnC, D-ARGININE, ...
著者Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y.
登録日2022-08-22
公開日2023-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
2GHQ
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BU of 2ghq by Molmil
CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
著者Zhang, Y, Noel, J.P.
登録日2006-03-27
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
5IRN
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BU of 5irn by Molmil
Crystal structure of rabbit NOD2 in an ADP-bound state (Crystal form1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Uncharacterized protein
著者Maekawa, S, Ohto, U, Shimizu, T.
登録日2016-03-14
公開日2016-06-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal structure of NOD2 and its implications in human disease.
Nat Commun, 7, 2016
4ETU
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BU of 4etu by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant R2939S
分子名称: GLYCEROL, Ryanodine receptor 1
著者Yuchi, Z, Lau, K, Van Petegem, F.
登録日2012-04-24
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4GJS
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BU of 4gjs by Molmil
Streptavidin-K121H
分子名称: Rhodium, Streptavidin, trichloro{(1,2,3,4,5-eta)-1,2,3,4-tetramethyl-5-[2-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]cyclopentadienyl}rhodium(1+)
著者Heinisch, T, Schirmer, T.
登録日2012-08-10
公開日2013-02-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology.
J.Am.Chem.Soc., 135, 2013
5IS2
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BU of 5is2 by Molmil
Crystal structure of Mycobacterium avium SerB2 at pH 6.6
分子名称: MAGNESIUM ION, Phosphoserine phosphatase
著者Shree, S, Ramachandran, R.
登録日2016-03-15
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.881 Å)
主引用文献Crystal Structure of Mycobacterium avium SerB2 (MAV_3907) at pH 6.6
To be published
7DDX
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BU of 7ddx by Molmil
Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1
分子名称: Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ...
著者Pan, W, Xu, Y, Wei, Z.
登録日2020-10-30
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.
J.Biol.Chem., 297, 2021
7Z6O
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BU of 7z6o by Molmil
X-Ray studies of Ku70/80 reveal the binding site for IP6
分子名称: DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ...
著者Varela, P.F, Charbonnier, J.B.
登録日2022-03-14
公開日2023-08-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Nucleic Acids Res., 51, 2023
2G81
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BU of 2g81 by Molmil
Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with Beta-trypsin at 1.55 Angstrons Resolution
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Bowman-Birk type seed trypsin and chymotrypsin inhibitor, ...
著者Freitas, S.M, Barbosa, J.A.R.G, Paulino, L.S, Teles, R.C.L, Esteves, G.F, Ventura, M.M.
登録日2006-03-01
公開日2007-01-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with {beta}-Trypsin at 1.55 A Resolution and Its Structural Properties in Association with Proteinases
Biophys.J., 92, 2007
5ISK
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BU of 5isk by Molmil
Endothiapepsin in complex with fluorinated primary amine fragment
分子名称: 2-amino-1-(4-fluorophenyl)ethan-1-one, ACETATE ION, DIMETHYL SULFOXIDE, ...
著者Radeva, N, Heine, A, Klebe, G.
登録日2016-03-15
公開日2017-03-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Crystallographic Fragment Screening of an Entire Library
to be published

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件を2024-07-17に公開中

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