6OC1
 
 | | Crystal structure of human DHODH with TAK-632 | | 分子名称: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Durst, M.A, Lavie, A. | | 登録日 | 2019-03-21 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism.
Cell Chem Biol, 27, 2020
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6OCN
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3FLK
 | | Crystal Structure of Tartrate Dehydrogenase from Pseudomonas putida in complex with NADH, oxalate and metal ion | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AMMONIUM ION, ... | | 著者 | Malik, R, Viola, R.E. | | 登録日 | 2008-12-18 | | 公開日 | 2009-12-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization of tartrate dehydrogenase: a versatile enzyme catalyzing multiple reactions.
Acta Crystallogr.,Sect.D, 66, 2010
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4B75
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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2RM9
 | | Astressin2B | | 分子名称: | Astressin2B | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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6OHB
 | | E. coli Guanine Deaminase | | 分子名称: | Guanine deaminase, ZINC ION | | 著者 | Shek, R.S, French, J.B. | | 登録日 | 2019-04-05 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily.
Biochemistry, 58, 2019
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2RME
 | | Stressin | | 分子名称: | Stressin | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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6XP5
 | | Head-Middle module of Mediator | | 分子名称: | HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ... | | 著者 | Zhang, H.Q, Chen, D.C, Kornberg, R.D. | | 登録日 | 2020-07-08 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mediator structure and conformation change.
Mol.Cell, 81, 2021
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6ON4
 | | Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid | | 分子名称: | HTH-type transcriptional repressor NanR, N-acetyl-beta-neuraminic acid, ZINC ION, ... | | 著者 | Horne, C.R, Panjikar, S, North, R.A, Dobson, R.C.J. | | 登録日 | 2019-04-19 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Control of the Escherichia coli sialoregulon by transcriptional repressor NanR.
J. Bacteriol., 195, 2013
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6ONB
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, monoclinic form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NeuRonal IgCAM-5, ... | | 著者 | Cheng, S, Kurleto, J.D, Ozkan, E. | | 登録日 | 2019-04-20 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OOX
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6O4D
 | | Structure of ALDH7A1 mutant W175A complexed with L-pipecolic acid | | 分子名称: | 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Tanner, J.J, Korasick, D.A, Laciak, A.R. | | 登録日 | 2019-02-28 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
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6ICD
 | | REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE | | 分子名称: | ISOCITRATE DEHYDROGENASE | | 著者 | Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M. | | 登録日 | 1990-05-30 | | 公開日 | 1991-10-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
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6OBR
 | | PP1 Y134A in complex with Microcystin LR | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Microcystin LR, ... | | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | | 登録日 | 2019-03-21 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2RMH
 | | Human Urocortin 3 | | 分子名称: | Urocortin-3 | | 著者 | Grace, C.R.R, Perrin, M.H, Cantle, J.P, Vale, W.W, Rivier, J.E, Riek, R. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Common and divergent structural features of a series of corticotropin releasing factor-related peptides
J.Am.Chem.Soc., 129, 2007
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6O4B
 | | Structure of ALDH7A1 mutant W175G complexed with NAD | | 分子名称: | 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ... | | 著者 | Tanner, J.J, Korasick, D.A, Laciak, A.R. | | 登録日 | 2019-02-28 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
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6ON9
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, tetragonal form | | 分子名称: | NeuRonal IgCAM-5, SODIUM ION, SULFATE ION, ... | | 著者 | Cheng, S, Kurleto, J.D, Ozkan, E. | | 登録日 | 2019-04-20 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6O9N
 | | Structural insights on a new fungal aryl-alcohol oxidase | | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kadowaki, M.A.S, Polikarpov, I. | | 登録日 | 2019-03-14 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77.
Biochim Biophys Acta Gen Subj, 1864, 2020
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6OBS
 | | PP1 Y134K | | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | | 登録日 | 2019-03-21 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OCK
 | | Crystal Structure of Leporine Serum Albumin in Complex with Ketoprofen | | 分子名称: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, (2R)-2-{[(2R)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propan-1-ol, (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, ... | | 著者 | Zielinski, K, Sekula, B, Bujacz, A, Bujacz, G. | | 登録日 | 2019-03-24 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural investigations of stereoselective profen binding by equine and leporine serum albumins.
Chirality, 32, 2020
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6OFY
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3F8T
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6OHA
 | | Yeast Guanine Deaminase | | 分子名称: | PENTAETHYLENE GLYCOL, Probable guanine deaminase, SULFATE ION, ... | | 著者 | Shek, R.S, French, J.B. | | 登録日 | 2019-04-05 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily.
Biochemistry, 58, 2019
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8K6Q
 | | Crystal structure of HOIL-1L LTM domain | | 分子名称: | RanBP-type and C3HC4-type zinc finger-containing protein 1 | | 著者 | Yan, Z, Pan, L.F. | | 登録日 | 2023-07-25 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
Biochem.Biophys.Res.Commun., 689, 2023
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6OC5
 | | Lanthanide-dependent methanol dehydrogenase XoxF from Methylobacterium extorquens, in complex with Lanthanum | | 分子名称: | LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF | | 著者 | Fellner, M, Good, N.M, Martinez-Gomez, N.C, Hausinger, R.P, Hu, J. | | 登録日 | 2019-03-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function.
J.Biol.Chem., 295, 2020
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