PDB: 184249 件ウェブページステータス検索Chemie searchBIRD

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6FHJ	Structural dynamics and catalytic properties of a multi-modular xanthanase, native. 分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Moroz, O.V, Jensen, P.F, McDonald, S.P, McGregor, N, Blagova, E, Comamala, G, Segura, D.R, Anderson, L, Vasu, S.M, Rao, V.P, Giger, L, Monrad, R.N, Svendsen, A, Nielsen, J.E, Henrissat, B, Davies, G.J, Brumer, H, Rand, K, Wilson, K.S. 登録日 2018-01-14 公開日 2018-08-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase Acs Catalysis, 2018
7N1P	Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, S.K, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. 登録日 2021-05-28 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.33 Å) 主引用文献 Structural basis of early translocation events on the ribosome. Nature, 595, 2021
6OGI	70S termination complex with RF2 bound to the UAG codon. Rotated ribosome conformation (Structure V) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. 登録日 2019-04-02 公開日 2019-09-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
6OI2	Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine 分子名称: GLYCEROL, N3, N4-DIMETHYLARGININE, ... 著者 Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. 登録日 2019-04-08 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
4ER3	Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777 分子名称: 1,2-ETHANEDIOL, 7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Histone-lysine N-methyltransferase, ... 著者 Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2012-04-19 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
5FOW	HUMANISED MONOMERIC RADA IN COMPLEX WITH WHTA TETRAPEPTIDE 分子名称: DNA repair and recombination protein RadA, PHOSPHATE ION, WHTA PEPTIDE 著者 Scott, D.E, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. 登録日 2015-11-26 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Structure Activity Relationship of the Peptide Binding Motif Mediating the Rad51:Brca2 Protein-Protein Interaction. FEBS Lett., 590, 2016
6SVY	Crystal structure of Neprilysin in complex with Sampatrilat-ASP. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neprilysin, Sampatrilat-Asp, ... 著者 Cozier, G.E, Acharya, K.R, Sharma, U. 登録日 2019-09-19 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme. J.Med.Chem., 63, 2020
7O0T	Crystal structure of Chloroflexus aggregans ene-reductase CaOYE holoenzyme 分子名称: FLAVIN MONONUCLEOTIDE, MALONATE ION, NADH:flavin oxidoreductase/NADH oxidase 著者 Robescu, M.S, Niero, M, Loprete, G, Bergantino, E, Cendron, L. 登録日 2021-03-26 公開日 2021-05-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A New Thermophilic Ene-Reductase from the Filamentous Anoxygenic Phototrophic Bacterium Chloroflexus aggregans . Microorganisms, 9, 2021
7NQL	55S mammalian mitochondrial ribosome with ICT1 and P site tRNAMet 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ... 著者 Kummer, E, Schubert, K, Ban, N. 登録日 2021-03-01 公開日 2021-05-05 最終更新日 2021-12-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
7NQH	55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ... 著者 Kummer, E, Schubert, K, Ban, N. 登録日 2021-03-01 公開日 2021-05-05 最終更新日 2021-12-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
5D7I	Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR 分子名称: Beta-2-microglobulin, GLYCEROL, M33.64 TCR Alpha Chain, ... 著者 Keller, A.N, Woolley, R.E, Rossjohn, J. 登録日 2015-08-14 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition. Immunity, 44, 2016
7XC2	Cryo EM structure of oligomeric complex formed by wheat CNL Sr35 and the effector AvrSr35 of the wheat stem rust pathogen 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Avirulence factor, CNL9 著者 Alexander, F, Li, E.T, Aaron, L, Deng, Y.N, Sun, Y, Chai, J.J. 登録日 2022-03-22 公開日 2022-09-21 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A wheat resistosome defines common principles of immune receptor channels. Nature, 610, 2022
5FOV	HUMANISED MONOMERIC RADA IN COMPLEX WITH FHTG TETRAPEPTIDE 分子名称: DNA repair and recombination protein RadA, FHTG PEPTIDE, GLYCEROL, ... 著者 Scott, D.E, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. 登録日 2015-11-26 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.739 Å) 主引用文献 Structure Activity Relationship of the Peptide Binding Motif Mediating the Rad51:Brca2 Protein-Protein Interaction. FEBS Lett., 590, 2016
6Q9W	X-ray structure of compound 15 bound to HdmX: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes 分子名称: (4~{S})-4-(4-chlorophenyl)-5-[(1~{S})-1-(3-chlorophenyl)ethyl]-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Protein Mdm4, ... 著者 Kallen, J. 登録日 2018-12-18 公開日 2019-05-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. Chemmedchem, 14, 2019
6G9I	Crystal structure of Ebolavirus glycoprotein in complex with clomipramine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Envelope glycoprotein,Envelope glycoprotein, ... 著者 Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. 登録日 2018-04-10 公開日 2018-05-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61, 2018
5ER4	Crystal Structure of Calcium-loaded S100B bound to SC0025 分子名称: 6-methyl-5,6,6~{a},7-tetrahydro-4~{H}-dibenzo[de,g]quinoline-10,11-diol, CALCIUM ION, Protein S100-B 著者 Cavalier, M.C, Melville, Z.E, Aligholizadeh, E, Fang, L, Alasady, M.J, Pierce, A.D, Wilder, P.T, MacKerell Jr, A.D, Weber, D.J. 登録日 2015-11-13 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.813 Å) 主引用文献 Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography. Acta Crystallogr D Struct Biol, 72, 2016
7NSH	39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2 分子名称: 16S rRNA, 39S ribosomal protein L48, mitochondrial, ... 著者 Kummer, E, Schubert, K, Ban, N. 登録日 2021-03-07 公開日 2021-05-05 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
5NFE	Neutron structure of human transthyretin (TTR) T119M mutant at room temperature to 1.85A resolution 分子名称: Transthyretin 著者 Yee, A.W, Moulin, M, Blakeley, M.P, Ostermann, A, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. 登録日 2017-03-14 公開日 2019-01-02 最終更新日 2024-05-01 実験手法 NEUTRON DIFFRACTION (1.853 Å), X-RAY DIFFRACTION 主引用文献 A molecular mechanism for transthyretin amyloidogenesis. Nat Commun, 10, 2019
4WEN	Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V2 分子名称: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC 著者 Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. 登録日 2014-09-10 公開日 2015-02-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies. Vet. Res., 46, 2015
8B0H	2C9, C5b9-CD59 cryoEM structure 分子名称: CD59 glycoprotein, Complement C5, Complement component C6, ... 著者 Couves, E.C, Gardner, S, Bubeck, D. 登録日 2022-09-07 公開日 2023-02-22 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
1Y1K	Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58A mutant 分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... 著者 Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. 登録日 2004-11-18 公開日 2005-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
6PXM	Horse spleen apoferritin light chain 分子名称: Ferritin light chain 著者 Kopylov, M, Kelley, K, Yen, L.Y, Rice, W.J, Eng, E.T, Carragher, B, Potter, C.S. 登録日 2019-07-26 公開日 2019-08-07 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Horse spleen apoferritin light chain structure at 2.1 Angstrom resolution To Be Published
6G4F	Crystal structure of the omega TRANSAMINASE FROM PSEUDOMONAS Jessenii in complex with PMP 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, GLYCEROL, ... 著者 Rozeboom, H.J, Janssen, D.B. 登録日 2018-03-27 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical properties of a Pseudomonas aminotransferase involved in caprolactam metabolism. Febs J., 286, 2019
1Y3F	Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 F69A mutant 分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... 著者 Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. 登録日 2004-11-24 公開日 2005-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
6NAG	X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron "iotapain 分子名称: Clostripain-related protein, PROLINE 著者 Wolan, D.W, Gonzalez-Paez, G.E, Roncase, E.J. 登録日 2018-12-05 公開日 2019-12-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.683 Å) 主引用文献 X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors. Biochemistry, 58, 2019

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