4QUU
 
 | | Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)5 | | 分子名称: | 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, Histone H4, ... | | 著者 | Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-07-12 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.
J Mol Cell Biol, 8, 2016
|
|
3TAS
 | | Small laccase from Streptomyces viridosporus T7A | | 分子名称: | ACETATE ION, COPPER (II) ION, OXYGEN MOLECULE, ... | | 著者 | Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K. | | 登録日 | 2011-08-04 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Roles of small laccases from Streptomyces in lignin degradation.
Biochemistry, 53, 2014
|
|
3TDO
 | | Crystal structure of HSC at pH 9.0 | | 分子名称: | Putative formate/nitrite transporter, TETRAETHYLENE GLYCOL, octyl beta-D-glucopyranoside | | 著者 | Czyzewski, B.K, Wang, D.-N. | | 登録日 | 2011-08-11 | | 公開日 | 2012-03-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | Identification and characterization of a bacterial hydrosulphide ion channel.
Nature, 483, 2012
|
|
4POP
 | | ThiT with LMG139 bound | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophene-2-carbaldehyde, ... | | 著者 | Swier, L.J.Y.M, Guskov, A, Slotboom, D.J. | | 登録日 | 2014-02-26 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
Chembiochem, 16, 2015
|
|
4PTW
 | | Halothermothrix orenii beta-glucosidase A, 2-deoxy-2-fluoro-glucose complex | | 分子名称: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, Glycoside hydrolase family 1, TETRAETHYLENE GLYCOL | | 著者 | Hassan, N, Nguyen, T.H, Kori, L.D, Patel, B.K.C, Haltrich, D, Divne, C, Tan, T.C. | | 登録日 | 2014-03-11 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biochemical and structural characterization of a thermostable beta-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis.
Appl.Microbiol.Biotechnol., 99, 2015
|
|
5OAR
 | | Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ... | | 著者 | Skerlova, J, Rezacova, P, Brynda, J, Pachl, P, Otwinowski, Z, Vanek, O. | | 登録日 | 2017-06-23 | | 公開日 | 2017-12-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide.
FEBS J., 285, 2018
|
|
2PEG
 | | Crystal structure of Trematomus bernacchii hemoglobin in a partial hemichrome state | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Vergara, A, Franzese, M, Merlino, A, Vitagliano, L, Mazzarella, L. | | 登録日 | 2007-04-03 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural characterization of ferric hemoglobins from three antarctic fish species of the suborder notothenioidei.
Biophys.J., 93, 2007
|
|
3T12
 | | MglA in complex with MglB in transition state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Gliding protein MglB, Gliding protein mglA, ... | | 著者 | Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A. | | 登録日 | 2011-07-21 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
|
|
3TDX
 | | Crystal structure of HSC L82V | | 分子名称: | CHLORIDE ION, TETRAETHYLENE GLYCOL, formate/nitrite transporter, ... | | 著者 | Czyzewski, B.K, Wang, D.-N. | | 登録日 | 2011-08-11 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification and characterization of a bacterial hydrosulphide ion channel.
Nature, 483, 2012
|
|
4LFU
 | | Crystal structure of Escherichia coli SdiA in the space group C2 | | 分子名称: | CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL | | 著者 | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | | 登録日 | 2013-06-27 | | 公開日 | 2014-03-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
|
|
5VC1
 | | Crystal structure of L-selectin lectin/EGF domains | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Wedepohl, S, Dernedde, J, Vahedi-Faridi, A, Tauber, R, Saenger, W, Bulut, H. | | 登録日 | 2017-03-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 angstrom Resolution.
Chembiochem, 18, 2017
|
|
1AH4
 | | PIG ALDOSE REDUCTASE, HOLO FORM | | 分子名称: | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Moras, D, Podjarny, A. | | 登録日 | 1997-04-12 | | 公開日 | 1998-04-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure, 5, 1997
|
|
4KU1
 | | Role of the hinge and C-gamma-2/C-gamma-3 interface in immunoglobin G1 Fc domain motions: implications for Fc engineering | | 分子名称: | Ig gamma-1 chain C region, TETRAETHYLENE GLYCOL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Frank, M, Walker, R, Lanzilotta, W.N, Prestegard, J.H, Barb, A.W. | | 登録日 | 2013-05-21 | | 公開日 | 2014-02-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Immunoglobulin g1 fc domain motions: implications for fc engineering.
J.Mol.Biol., 426, 2014
|
|
4EKD
 | |
4KVK
 | | Crystal structure of Oryza sativa fatty acid alpha-dioxygenase | | 分子名称: | CALCIUM ION, CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, ... | | 著者 | Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | | 登録日 | 2013-05-22 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide.
Protein Sci., 22, 2013
|
|
4KY0
 | | Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis | | 分子名称: | Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL | | 著者 | Guskov, A, Jensen, S, Rempel, S, Hanelt, I, Slotboom, D.J. | | 登録日 | 2013-05-28 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of a substrate-free aspartate transporter.
Nat.Struct.Mol.Biol., 20, 2013
|
|
4EUI
 | | Crystal Structure of MIF L46F mutant | | 分子名称: | Macrophage migration inhibitory factor, SULFATE ION | | 著者 | Ashrafi, A, Pojer, F, Lashuel, H. | | 登録日 | 2012-04-25 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
Plos One, 7, 2012
|
|
5U81
 | | Acid ceramidase (ASAH1, aCDase) from naked mole rat, Cys143Ala, uncleaved | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid ceramidase isoform b, CHLORIDE ION, ... | | 著者 | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2016-12-13 | | 公開日 | 2018-03-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
|
|
3RZA
 | |
4RIK
 | | Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | | 分子名称: | Alpha-synuclein | | 著者 | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | | 登録日 | 2014-10-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | | 主引用文献 | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
|
|
4ESV
 | | A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ... | | 著者 | Itsathitphaisarn, O, Wing, R.A, Eliason, W.K, Wang, J, Steitz, T.A. | | 登録日 | 2012-04-23 | | 公開日 | 2012-10-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation.
Cell(Cambridge,Mass.), 151, 2012
|
|
1TFT
 | | NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP | | 分子名称: | 1-[3,3-DIMETHYL-2-(2-METHYLAMINO-PROPIONYLAMINO)-BUTYRYL]-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-AMIDE, Baculoviral IAP repeat-containing protein 4, ZINC ION | | 著者 | Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A.K, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W. | | 登録日 | 2004-05-27 | | 公開日 | 2005-05-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.
J.Med.Chem., 47, 2004
|
|
5TTZ
 | |
4DQK
 | |
3SB4
 | |
