PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4NZI	Crystal structure of murine neuroglobin mutant V140W 分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Avella, G, Savino, C, Vallone, B. 登録日 2013-12-12 公開日 2014-06-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
3H9N	Crystal structure of the ribosome maturation factor rimm (hi0203) from h.influenzae. northeast structural genomics consortium target IR66. 分子名称: Ribosome maturation factor rimM, SULFATE ION 著者 Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Maglaqui, M, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-04-30 公開日 2009-05-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Northeast Structural Genomics Consortium Target IR66 To be Published
4O07	Identification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's disease 分子名称: 2,7,7-trimethyl-9-[8-(2-methylpropyl)-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl]-1,2,3,4,6,7,8,9-octahydro-5H-beta-carbolin-5-one, Heat shock protein HSP 90-alpha 著者 Zuccola, H.J, Ernst, J.T. 登録日 2013-12-13 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Identification of Novel HSP90 alpha / beta Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington's Disease. J.Med.Chem., 57, 2014
3GOC	Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196 分子名称: 3-(2-hydroxyethyl)-2,2-bis(hydroxymethyl)pentane-1,5-diol, CHLORIDE ION, Endonuclease V, ... 著者 Forouhar, F, Abashidze, M, Hussain, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Owens, L, Chen, C.X, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2009-03-18 公開日 2009-03-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196. To be Published
3GQH	Crystal Structure of the Bacteriophage phi29 gene product 12 C-terminal fragment 分子名称: Preneck appendage protein 著者 Xiang, Y, Rossmann, M.G. 登録日 2009-03-24 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike. Mol.Cell, 34, 2009
3UIO	Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II 分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... 著者 Gareau, J.R, Reverter, D, Lima, C.D. 登録日 2011-11-05 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
3GR8	Structure of OYE from Geobacillus kaustophilus, orthorhombic crystal form 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase, ... 著者 Uhl, M.K, Gruber, K. 登録日 2009-03-25 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Old Yellow Enzyme-Catalyzed Dehydrogenation of Saturated Ketones ADV.SYNTH.CATAL., 353, 2011
4NZG	Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Integrase p46, ... 著者 Guan, R, Jiang, M, Janjua, H, Maglaqui, M, Zhao, L, Xiao, R, Acton, T.B, Everett, J.K, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2013-12-12 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
3UDP	Crystal Structure of BACE with Compound 12 分子名称: (4S)-6-bromo-3,4-dihydro-2H-thiochromen-4-yl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate, 1,2-ETHANEDIOL, Beta-secretase 1, ... 著者 Efremov, I.V, Vajdos, F.F, Borzilleri, K, Capetta, S, Dorff, P, Dutra, J, Mansour, M, Oborski, C, O'Connell, T, O'Sullivan, T.J, Pandit, J, Wang, H, Withka, J. 登録日 2011-10-28 公開日 2012-04-18 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and optimization of a novel spiropyrrolidine inhibitor of {beta}-secretase (BACE1) through fragment-based drug design. J.Med.Chem., 55, 2012
3GO0	Crystal structure of D-enantiomer of human alpha-defensin 1 (D-HNP1) 分子名称: CHLORIDE ION, Neutrophil defensin 1 著者 Pazgier, M, Lu, W.-Y. 登録日 2009-03-18 公開日 2009-07-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Through the looking glass, mechanistic insights from enantiomeric human defensins. J.Biol.Chem., 284, 2009
3GXM	Crystal structure of acid-beta-glucosidase at pH 4.5, phosphate crystallization condition 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, SULFATE ION 著者 Lieberman, R.L. 登録日 2009-04-02 公開日 2009-05-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability. Biochemistry, 48, 2009
3GZG	Crystal structure of the Xanthomonas axonopodis pv. citri molybdate-binding protein (ModA) mutant (K127S) 分子名称: MOLYBDATE ION, Molybdate-binding periplasmic protein; permease, SULFATE ION 著者 Santacruz-Perez, C, Pegos, V.R, Balan, A, Barbosa, J.A.R.G. 登録日 2009-04-07 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of the Xanthomonas axonopodis pv. citri molybdate-binding protein (ModA) mutant (K127S) To be Published
4O35	Crystal structure of carbomonoxy murine neuroglobin mutant F106W 分子名称: 1,4-DIETHYLENE DIOXIDE, CARBON MONOXIDE, Neuroglobin, ... 著者 Avella, G, Savino, C, Vallone, B. 登録日 2013-12-18 公開日 2014-06-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
3GW2	Crystal structure of possible transcriptional regulatory protein (fragment 1-100) from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR242E. 分子名称: Possible transcriptional regulatory arsR-family protein 著者 Kuzin, A.P, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2009-03-31 公開日 2009-04-21 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Northeast Structural Genomics Consortium Target MbR242E To be published
3HCA	Crystal Structure of E185Q hPNMT in Complex With Octopamine and AdoHcy 分子名称: 1,2-ETHANEDIOL, 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL, Phenylethanolamine N-methyltransferase, ... 著者 Drinkwater, N, Martin, J.L. 登録日 2009-05-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem.J., 422, 2009
3HCG	Structure of the C-terminal domain (MsrB) of Neisseria meningitidis PilB (reduced form) 分子名称: PHOSPHATE ION, Peptide methionine sulfoxide reductase msrA/msrB 著者 Ranaivoson, F.M, Kauffmann, B, Favier, F. 登録日 2009-05-06 公開日 2009-10-13 最終更新日 2014-04-09 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Methionine sulfoxide reductase B displays a high level of flexibility. J.Mol.Biol., 394, 2009
3UL5	Saccharum officinarum canecystatin-1 in space group C2221 分子名称: Canecystatin-1, GLYCEROL, SODIUM ION 著者 Valadares, N.F, Pereira, H.M, Oliveira-Silva, R, Garratt, R.C. 登録日 2011-11-10 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray crystallography and NMR studies of domain-swapped canecystatin-1. Febs J., 280, 2013
3UD5	Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1A 分子名称: 1,2-ETHANEDIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[1-(2-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine 著者 Shaw, G, Shi, G, Ji, X. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties. Bioorg.Med.Chem., 20, 2012
3HA2	Crystal Structure of Protein (NADPH-quinone reductase) from P.pentosaceus, Northeast Structural Genomics Consortium Target PtR24A 分子名称: DI(HYDROXYETHYL)ETHER, NADPH-quinone reductase, SULFATE ION 著者 Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Maglaqui, M, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-04-30 公開日 2009-05-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Northeast Structural Genomics Consortium Target PtR24A To be Published
4O9C	Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 分子名称: Acetyl-CoA acetyltransferase, COENZYME A 著者 Kim, E.J, Kim, J, Kim, S, Kim, K.J. 登録日 2014-01-02 公開日 2014-12-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium. Biochem.Biophys.Res.Commun., 452, 2014
3GOO	Strontium bound to the Holliday junction sequence d(TCGGCGCCGA)4 分子名称: 5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3', STRONTIUM ION 著者 Naseer, A, Cardin, C.J. 登録日 2009-03-19 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Strontium bound to the Holliday junction sequence d(TCGGCGCCGA)4 To be Published
3H6Z	Crystal Structure of the Four MBT Repeats of Drosophila melanogaster Sfmbt in Complex with Peptide RHR (me)K VLR 分子名称: 'HR(MLZ)VLR, Polycomb protein Sfmbt, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose 著者 Grimm, C, Mueller, C.W. 登録日 2009-04-24 公開日 2009-06-16 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt Embo J., 28, 2009
3GT0	Crystal structure of pyrroline 5-carboxylate reductase from Bacillus cereus. Northeast Structural Genomics Consortium Target BcR38B 分子名称: Pyrroline-5-carboxylate reductase 著者 Kuzin, A.P, Abashidze, M, Seetharaman, J, Shastry, R, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2009-03-27 公開日 2009-04-21 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Northeast Structural Genomics Consortium Target BcR38B To be published
4OM5	Crystal structure of CTX A4 from Taiwan Cobra (Naja naja atra) 分子名称: Cytotoxin 4 著者 Lin, C.C, Chang, C.I, Wu, W.G. 登録日 2014-01-26 公開日 2014-06-11 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface. J.Biol.Chem., 289, 2014
3GW4	Crystal structure of uncharacterized protein from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR162B. 分子名称: Uncharacterized protein 著者 Kuzin, A.P, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-03-31 公開日 2009-04-21 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Northeast Structural Genomics Consortium Target DrR162B To be published

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