PDB: 1555 件ウェブページステータス検索Chemie searchBIRD

---

6C7X	Carbonic anhydrase 2 in complex with 2-chloro-5'-O-sulfamoyladenosine 分子名称: 2-chloro-5'-O-sulfamoyladenosine, Carbonic anhydrase 2, SODIUM ION, ... 著者 Peat, T.S, Mujumdar, P, Poulsen, S.A. 登録日 2018-01-23 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Synthesis, structure and bioactivity of primary sulfamate-containing natural products. Bioorg. Med. Chem. Lett., 28, 2018
8B29	Human carbonic anhydrase II containing 6-fluorotryptophanes. 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Pham, L.B.T, Costantino, A, Barbieri, L, Calderone, V, Luchinat, E, Banci, L. 登録日 2022-09-13 公開日 2023-01-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Direct Expression of Fluorinated Proteins in Human Cells for 19 F In-Cell NMR Spectroscopy. J.Am.Chem.Soc., 145, 2023
2FKO	Structure of PH1591 from Pyrococcus horikoshii OT3 分子名称: 1,2-ETHANEDIOL, 173aa long hypothetical ferripyochelin binding protein, ZINC ION 著者 Jeyakanthan, J, Tahirov, T.H, Yokoyama, S, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-01-05 公開日 2007-01-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Observation of a calcium-binding site in the gamma-class carbonic anhydrase from Pyrococcus horikoshii. Acta Crystallogr.,Sect.D, 64, 2008
1IF8	Carbonic Anhydrase II Complexed With (S)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide 分子名称: (S)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I. 登録日 2001-04-12 公開日 2001-05-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Combinatorial computational method gives new picomolar ligands for a known enzyme. Proc.Natl.Acad.Sci.USA, 99, 2002
1IF7	Carbonic Anhydrase II Complexed With (R)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide 分子名称: (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Grzybowski, B.A, Ishchenko, A.V, Kim, C.-Y, Topalov, G, Chapman, R, Christianson, D.W, Whitesides, G.M, Shakhnovich, E.I. 登録日 2001-04-12 公開日 2001-05-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Combinatorial computational method gives new picomolar ligands for a known enzyme. Proc.Natl.Acad.Sci.USA, 99, 2002
4Y0J	H/D exchanged human carbonic anhydrase II pH 6 room temperature neutron crystal structure. 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Fisher, S.Z. 登録日 2015-02-06 公開日 2015-04-22 最終更新日 2024-01-10 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112, 2015
5EZT	Peracetylated Bovine Carbonic Anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Whitesides, G.M, Kang, K, Choi, J.-M, Fox, J.M. 登録日 2015-11-26 公開日 2016-07-20 最終更新日 2016-07-27 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts. J.Phys.Chem.B, 120, 2016
6H6S	Sad phasing on nickel-substituted human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, NICKEL (II) ION 著者 Calderone, V, Fragai, M, Silva, J.P, Luchinat, C, Ravera, E, Geraldes, C.F.G.C, Macedo, A.L, Cerofolini, L, Giuntini, S. 登録日 2018-07-30 公開日 2019-01-09 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects? J. Biol. Inorg. Chem., 24, 2019
3NI5	Carbonic anhydrase inhibitor: C1 family 分子名称: 4-(nitrooxy)butyl 3-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)sulfamoyl]benzoate, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Cecchi, A, Scozzafava, A, Supuran, C.T. 登録日 2010-06-15 公開日 2011-06-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action Bioorg.Med.Chem.Lett., 21, 2011
3P3J	Human carbonic anhydrase II in complex with p-(5-ruthenocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-05 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
3P3H	Human carbonic anhydrase II in complex with p-(5-ferrocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-04 公開日 2011-09-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
4Q49	Room temperature neutron crystal structure of apo human carbonic anhydrase at pH 7.5 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Fisher, S.Z, McKenna, R. 登録日 2014-04-14 公開日 2015-02-25 最終更新日 2023-09-20 実験手法 NEUTRON DIFFRACTION (1.8 Å) 主引用文献 Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112, 2015
1V67	Structure of ferripyochelin binding protein from pyrococcus horikoshii OT3 分子名称: BICARBONATE ION, CALCIUM ION, ZINC ION, ... 著者 Jeyakanthan, J, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-11-27 公開日 2003-12-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Observation of a calcium-binding site in the gamma-class carbonic anhydrase from Pyrococcus horikoshii. Acta Crystallogr.,Sect.D, 64, 2008
3P44	Human carbonic anhydrase II in complex with p-(4-ruthenocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-06 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
3P55	Human carbonic anhydrase II in complex with p-(4-ferrocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-07 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
1V3W	Structure of Ferripyochelin binding protein from Pyrococcus horikoshii OT3 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Jeyakanthan, J, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-11-07 公開日 2003-11-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Observation of a calcium-binding site in the gamma-class carbonic anhydrase from Pyrococcus horikoshii. Acta Crystallogr.,Sect.D, 64, 2008
6TL6	Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide 分子名称: Carbonic anhydrase 9, GLYCEROL, ZINC ION, ... 著者 Leitans, J, Tars, K. 登録日 2019-12-01 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle. Biophys.J., 119, 2020
1YLK	Crystal Structure of Rv1284 from Mycobacterium tuberculosis in Complex with Thiocyanate 分子名称: Hypothetical protein Rv1284/MT1322, THIOCYANATE ION, ZINC ION 著者 Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE) 登録日 2005-01-19 公開日 2005-03-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and function of carbonic anhydrases from Mycobacterium tuberculosis. J.Biol.Chem., 280, 2005
6KFS	Structure of CCM related protein 分子名称: LCIB_C_CA domain-containing protein, ZINC ION 著者 Jin, S, Gao, Y.G. 登録日 2019-07-08 公開日 2020-07-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum. Acta Crystallogr D Struct Biol, 76, 2020
7YWT	human Carbonic Anhydrase II in complex with 4-oxo-N-(4-sulfamoylphenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carboxamide 分子名称: (11~{b}~{R})-4-oxidanylidene-~{N}-(4-sulfamoylphenyl)-3,6,7,11~{b}-tetrahydro-1~{H}-pyrazino[2,1-a]isoquinoline-2-carboxamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Angeli, A, Ferraroni, M. 登録日 2022-02-14 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.106 Å) 主引用文献 Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37, 2022
2GD8	Crystal structure analysis of the human carbonic anhydrase II in complex with a 2-substituted estradiol bis-sulfamate 分子名称: (9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE, CHLORIDE ION, Carbonic anhydrase 2, ... 著者 De Simone, G, Di Fiore, A. 登録日 2006-03-15 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J.Med.Chem., 49, 2006
7YZH	Schistosoma Mansoni Carbonic Anhydrase in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide, Carbonic anhydrase, ... 著者 Angeli, A, Ferraroni, M. 登録日 2022-02-20 公開日 2023-03-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37, 2022
3VQJ	Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase 分子名称: Carbonyl sulfide hydrolase, SODIUM ION, ZINC ION 著者 Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. 登録日 2012-03-24 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
3VRK	Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex 分子名称: Carbonyl sulfide hydrolase, SODIUM ION, THIOCYANATE ION, ... 著者 Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. 登録日 2012-04-11 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
5O07	The crystal structure of the human carbonic anhydrase II in complex with a nitroimidazole sulfamate inhibitor 分子名称: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl sulfamate, Carbonic anhydrase 2, ZINC ION 著者 Alterio, V, De Simone, G, Esposito, D. 登録日 2017-05-16 公開日 2017-08-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations. J Enzyme Inhib Med Chem, 32, 2017

<45464748495051525354555657585960>